Reviewed, UniProtKB/Swiss-Prot Q0HV71 (ARAA_SHESR)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	Shewmr7_1995

Organism

Shewanella sp. (strain MR-7) [Complete proteome] [HAMAP]

Taxonomic identifier

60481 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	L-arabinose isomerase HAMAP MF_00519		PRO_0000312619
Sites
	Metal binding	306	1	Manganese By similarity
	Metal binding	333	1	Manganese By similarity
	Metal binding	349	1	Manganese By similarity
	Metal binding	448	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0HV71-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: FD9CC589BAB4F462	FASTA	500	55,305
	10 20 30 40 50 60 MKAFKQKQVW FITGSQDLYG PKVLEQVAKN SEQIVHGFNE SSAISIEVVY KPTVKSPREI 70 80 90 100 110 120 HAVCQAANSD ENCVGVILWM HTFSPAKMWI AGLNELSKPF MHLHTQFNAE LPWSEINMNY 130 140 150 160 170 180 MNTHQSAHGC REFGFIGTRM RKERKVVVGH WQSSDVQAQI DDWCRAAAGW HESQNLRIAR 190 200 210 220 230 240 FGDNMRQVAV TEGDKVAAQI QFGYEVHAYS LGELNEAIAA IAEGDVTAQL DRYASEYQVG 250 260 270 280 290 300 NELFGDEYQL DRLRKEAKIE LGLTQFLTQG GFGAFTNCFE NLTGMTGLPG LATQRLMANG 310 320 330 340 350 360 FGYGGEGDWK TAAMVRIMKV MGQGRAGGTS FMEDYTYNFG ATDQVLGAHM LEVCPSIAAA 370 380 390 400 410 420 KPRLEVHRHT IGVRCDVPRL LFTGKAGPAI NVSTIDLGNR FRIILNELDT VTPPQDLPNL 430 440 450 460 470 480 PVASALWEPR PNLAVAAAAW IHAGGAHHSA YSQAITTDQI VDFAEMAGAE LVIIDADTKI 490 500 REFKNELRQN SVYYGLARGL

References

[1]

"Complete sequence of chromosome 1 of Shewanella sp. MR-7." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K., Konstantinidis K., Klappenbach J., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000444 Genomic DNA. Translation: ABI42984.1.
RefSeq	YP_738041.1.
3D structure databases
SMR	Q0HV71. Positions 1-496.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0HV71.
Genome annotation databases
GeneID	4258681.
GenomeReviews	Gene locus Shewmr7_1995 in contig CP000444_GR.
KEGG	shm:Shewmr7_1995.
NMPDR	fig|60481.10.peg.1886.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2160.
HOGENOM	HBG297198.
OMA	EVCPTIA.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ARAA_SHESR

Accession

Primary (citable) accession number: Q0HV71

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	October 3, 2006
Last modified:	January 19, 2010
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)