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Protein

Ubiquinone biosynthesis O-methyltransferase

Gene

ubiG

Organism
Shewanella sp. (strain MR-7)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n.UniRule annotation
S-adenosyl-L-methionine + 3-(all-trans-polyprenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-polyprenyl)phenol.UniRule annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391S-adenosyl-L-methionineUniRule annotation
Binding sitei59 – 591S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
Binding sitei80 – 801S-adenosyl-L-methionineUniRule annotation
Binding sitei124 – 1241S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Ubiquinone biosynthesis

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciSSP60481:GHW6-2160-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquinone biosynthesis O-methyltransferaseUniRule annotation
Alternative name(s):
2-polyprenyl-6-hydroxyphenol methylaseUniRule annotation (EC:2.1.1.222UniRule annotation)
3-demethylubiquinone 3-O-methyltransferaseUniRule annotation (EC:2.1.1.64UniRule annotation)
Gene namesi
Name:ubiGUniRule annotation
Ordered Locus Names:Shewmr7_2060
OrganismiShewanella sp. (strain MR-7)
Taxonomic identifieri60481 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000001960 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 236236Ubiquinone biosynthesis O-methyltransferasePRO_1000013926Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ0HV07.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. UbiG/COQ3 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000278065.
KOiK00568.
OMAiVDQHAKA.
OrthoDBiEOG6D5G4H.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00472. UbiG.
InterProiIPR029063. SAM-dependent_MTases.
IPR010233. UbiG_MeTrfase.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR01983. UbiG. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0HV07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQNTNVDPQ EIAKFERMAE TWWDLNGEFK PLHLLNPLRL NYIDQTAGGI
60 70 80 90 100
FGKKVLDVGC GGGILSESMA RIGAIVHGLD MGEEPLEVAR LHALETGVSI
110 120 130 140 150
NYVKNTAEAH REDHREYYDV VTCMEMLEHV PDPLSVIQAC CDMVKPGGFV
160 170 180 190 200
FFSTINRNIK SFVETIIGAE YLLKMLPIGT HDHNKFIKPS ELMALVDNTD
210 220 230
LLCKDALGIT YNPLTGIFKY TPKVDVNYMI ATQKVD
Length:236
Mass (Da):26,432
Last modified:October 3, 2006 - v1
Checksum:i42CFE6E91E5511F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000444 Genomic DNA. Translation: ABI43048.1.
RefSeqiWP_011626219.1. NC_008322.1.

Genome annotation databases

EnsemblBacteriaiABI43048; ABI43048; Shewmr7_2060.
KEGGishm:Shewmr7_2060.
PATRICi23589231. VBISheSp85603_2124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000444 Genomic DNA. Translation: ABI43048.1.
RefSeqiWP_011626219.1. NC_008322.1.

3D structure databases

ProteinModelPortaliQ0HV07.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABI43048; ABI43048; Shewmr7_2060.
KEGGishm:Shewmr7_2060.
PATRICi23589231. VBISheSp85603_2124.

Phylogenomic databases

HOGENOMiHOG000278065.
KOiK00568.
OMAiVDQHAKA.
OrthoDBiEOG6D5G4H.

Enzyme and pathway databases

UniPathwayiUPA00232.
BioCyciSSP60481:GHW6-2160-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00472. UbiG.
InterProiIPR029063. SAM-dependent_MTases.
IPR010233. UbiG_MeTrfase.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR01983. UbiG. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-7.

Entry informationi

Entry nameiUBIG_SHESR
AccessioniPrimary (citable) accession number: Q0HV07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: May 11, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.