Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0HT75

- LPXB_SHESR

UniProt

Q0HT75 - LPXB_SHESR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Shewanella sp. (strain MR-7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciSSP60481:GHW6-2811-MONOMER.
UniPathwayiUPA00359; UER00481.

Protein family/group databases

CAZyiGT19. Glycosyltransferase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
Gene namesi
Name:lpxBUniRule annotation
Ordered Locus Names:Shewmr7_2695
OrganismiShewanella sp. (strain MR-7)
Taxonomic identifieri60481 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001960: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 385385Lipid-A-disaccharide synthasePRO_1000049420Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi60481.Shewmr7_2695.

Structurei

3D structure databases

ProteinModelPortaliQ0HT75.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018003.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0HT75-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKKSQLVFA MVAGELSGDI LGAGLMAALQ KTHPNARFVG IGGPRMEALG
60 70 80 90 100
FESLFAMEEL AVMGIVEVLS RLPRLLHVRS SLIKSITELK PDCFIGIDAP
110 120 130 140 150
DFNIGLELKL KAQGIKTVHY VSPSVWAWRP KRIFKIAKAT NMVLSLLPFE
160 170 180 190 200
KAFYDKHQVP CTFVGHTLAD DIPLESDKAS ARQLLELDPD AEYLAILPGS
210 220 230 240 250
RGGELKQLAE PFVKAALLIK QQFPDIRFVT PLVNQKRREQ FEQALKAHAP
260 270 280 290 300
DLEIHMVEGK SREVMAAADG ILLASGTATL EAMLIKRPMV VAYRVSPLTY
310 320 330 340 350
EIAKTMMQVN RFSLPNLLAG RDVVPELIQH DCTPEKIAAA VGVELNRDFA
360 370 380
PIKAEFERLH QLLRCDASQK AAEAVLALVD AKELN
Length:385
Mass (Da):42,434
Last modified:October 3, 2006 - v1
Checksum:iD1197537D36764A3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000444 Genomic DNA. Translation: ABI43680.1.
RefSeqiWP_011626703.1. NC_008322.1.
YP_738737.1. NC_008322.1.

Genome annotation databases

EnsemblBacteriaiABI43680; ABI43680; Shewmr7_2695.
GeneIDi4256056.
KEGGishm:Shewmr7_2695.
PATRICi23590573. VBISheSp85603_2782.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000444 Genomic DNA. Translation: ABI43680.1 .
RefSeqi WP_011626703.1. NC_008322.1.
YP_738737.1. NC_008322.1.

3D structure databases

ProteinModelPortali Q0HT75.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 60481.Shewmr7_2695.

Protein family/group databases

CAZyi GT19. Glycosyltransferase Family 19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI43680 ; ABI43680 ; Shewmr7_2695 .
GeneIDi 4256056.
KEGGi shm:Shewmr7_2695.
PATRICi 23590573. VBISheSp85603_2782.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018003.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci SSP60481:GHW6-2811-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-7.

Entry informationi

Entry nameiLPXB_SHESR
AccessioniPrimary (citable) accession number: Q0HT75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3