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Q0HSJ5 (ACPS_SHESR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Holo-[acyl-carrier-protein] synthase

Short name=Holo-ACP synthase
EC=2.7.8.7
Alternative name(s):
4'-phosphopantetheinyl transferase AcpS
Gene names
Name:acpS
Ordered Locus Names:Shewmr7_2926
OrganismShewanella sp. (strain MR-7) [Complete proteome] [HAMAP]
Taxonomic identifier60481 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length127 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP-Rule MF_00101

Catalytic activity

CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP-Rule MF_00101

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00101

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00101.

Sequence similarities

Belongs to the P-Pant transferase superfamily. AcpS family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

macromolecule biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionholo-[acyl-carrier-protein] synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 127127Holo-[acyl-carrier-protein] synthase HAMAP-Rule MF_00101
PRO_1000008498

Sites

Metal binding91Magnesium By similarity
Metal binding581Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0HSJ5 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 3CA5D061F980A410

FASTA12713,622
        10         20         30         40         50         60 
MAIVGLGTDI VEIERITAHV ARSGDKLAKR VLTEAEFEIY QQHSQPSRYL AKRFAAKEAA 

        70         80         90        100        110        120 
AKALGTGIGR GVSFQHIHIG NTPDGAPTID FTQGAQQRLA LLNGVVGHIS IADEKSYAIA 


TVILESR 

« Hide

References

[1]"Complete sequence of chromosome 1 of Shewanella sp. MR-7."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K., Konstantinidis K., Klappenbach J., Tiedje J., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MR-7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000444 Genomic DNA. Translation: ABI43910.1.
RefSeqYP_738967.1. NC_008322.1.

3D structure databases

ProteinModelPortalQ0HSJ5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING60481.Shewmr7_2926.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI43910; ABI43910; Shewmr7_2926.
GeneID4256795.
KEGGshm:Shewmr7_2926.
PATRIC23591047. VBISheSp85603_3019.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0736.
HOGENOMHOG000014316.
KOK00997.
OMAVHVSITH.
OrthoDBEOG6384R9.
ProtClustDBPRK00070.

Enzyme and pathway databases

BioCycSSP60481:GHW6-3044-MONOMER.

Family and domain databases

Gene3D3.90.470.20. 1 hit.
HAMAPMF_00101. AcpS.
InterProIPR008278. 4-PPantetheinyl_Trfase_SF.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase_dom.
[Graphical view]
PfamPF01648. ACPS. 1 hit.
[Graphical view]
ProDomPD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56214. SSF56214. 1 hit.
TIGRFAMsTIGR00516. acpS. 1 hit.
TIGR00556. pantethn_trn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACPS_SHESR
AccessionPrimary (citable) accession number: Q0HSJ5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families