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Protein

3-octaprenyl-4-hydroxybenzoate carboxy-lyase

Gene

ubiD

Organism
Shewanella sp. (strain MR-4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.UniRule annotation

Catalytic activityi

A 4-hydroxy-3-polyprenylbenzoate = a 2-polyprenylphenol + CO2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • prenyl-FMNUniRule annotationNote: Binds 1 prenylated FMN (prenyl-FMN) per subunit.UniRule annotation
  • Mn2+UniRule annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi172ManganeseUniRule annotation1
Metal bindingi238ManganeseUniRule annotation1
Active sitei287Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylase, Lyase
Biological processUbiquinone biosynthesis
LigandFlavoprotein, FMN, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciSSP60480:G1G76-532-MONOMER
UniPathwayiUPA00232

Names & Taxonomyi

Protein namesi
Recommended name:
3-octaprenyl-4-hydroxybenzoate carboxy-lyaseUniRule annotation (EC:4.1.1.98UniRule annotation)
Alternative name(s):
Polyprenyl p-hydroxybenzoate decarboxylaseUniRule annotation
Gene namesi
Name:ubiDUniRule annotation
Ordered Locus Names:Shewmr4_0506
OrganismiShewanella sp. (strain MR-4)
Taxonomic identifieri60480 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002676971 – 4933-octaprenyl-4-hydroxybenzoate carboxy-lyaseAdd BLAST493

Proteomic databases

PRIDEiQ0HMY1

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ0HMY1
SMRiQ0HMY1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni175 – 177Prenyl-FMN bindingUniRule annotation3
Regioni189 – 191Prenyl-FMN bindingUniRule annotation3
Regioni194 – 195Prenyl-FMN bindingUniRule annotation2

Sequence similaritiesi

Belongs to the UbiD family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000227663
KOiK03182
OMAiIDATNKW

Family and domain databases

HAMAPiMF_01636 UbiD, 1 hit
InterProiView protein in InterPro
IPR002830 UbiD
IPR023677 UbiD_bacteria
PfamiView protein in Pfam
PF01977 UbiD, 1 hit
TIGRFAMsiTIGR00148 TIGR00148, 1 hit

Sequencei

Sequence statusi: Complete.

Q0HMY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFKDLRSFI DHLEANGELK RISYPVDPHL EMTEIADRVL RAKGPALLFE
60 70 80 90 100
NPTNHSMPVL ANLFGTPKRV AMALGKEDPL ALRDVGELLA FLKEPEPPRG
110 120 130 140 150
FKDAISKIPM FKQALNMPPK TVRNPACQQV VKTGDEVDLT QLPIQHCWPG
160 170 180 190 200
DVAPLVTWGL TITKGPRKSR QNLGIYRQQL LGKNKLIMRW LSHRGGALDF
210 220 230 240 250
ADFKEQFPGE RYPVVVALGS DPVTILGAVT PVPDAMSEYA FAGLLRGERT
260 270 280 290 300
EVCKALSCDL EVPASSEIIL EGYIDPDEMA EEGPYGDHTG YYNETDKFPV
310 320 330 340 350
FTVTHITHRK DPIYHSTYTG RPPDEPAMLG VALNEVFVPI LRKQYPEIID
360 370 380 390 400
FYLPPEGCSY RMAVISIRKQ YPGHAKRVMM GAWSFLRQFM YTKFIVVVDD
410 420 430 440 450
DVNCRDWNDV IWAITTRMDP KRDTVMIDNT PIDYLDFASP VAGLGSKMGL
460 470 480 490
DATNKREGET NREWGTPIVM DPKVKQKIDS IWDELGIDDS PTL
Length:493
Mass (Da):55,464
Last modified:October 3, 2006 - v1
Checksum:i20D8CDE52F017B3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000446 Genomic DNA Translation: ABI37586.1
RefSeqiWP_011621308.1, NC_008321.1

Genome annotation databases

EnsemblBacteriaiABI37586; ABI37586; Shewmr4_0506
KEGGishe:Shewmr4_0506

Similar proteinsi

Entry informationi

Entry nameiUBID_SHESM
AccessioniPrimary (citable) accession number: Q0HMY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 3, 2006
Last modified: May 23, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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