Q0HMN9 (HFQ_SHESM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein hfq

Gene names

Name:	hfq
Ordered Locus Names:	Shewmr4_0598

Organism

Shewanella sp. (strain MR-4) [Complete proteome] [HAMAP]

Taxonomic identifier

60480 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	90 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs By similarity. HAMAP-Rule MF_00436
Subunit structure	Homohexamer By similarity.
Sequence similarities	Belongs to the hfq family.

Ontologies

Keywords
Biological process	Stress response
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 90	90	Protein hfq HAMAP-Rule MF_00436		PRO_0000265189

Sequences

	Sequence		Length	Mass (Da)
	Q0HMN9 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 92A98E29902BB917	FASTA	90	9,873
	10 20 30 40 50 60 MAKGQSLQDP FLNALRRERV PVSIYLVNGI KLQGQVESFD QFVILLKNTV SQMVYKHAIS 70 80 90 TVVPARPFNV AGHQNAQGGY GAQDDMPSGE

References

[1]

"Complete sequence of Shewanella sp. MR-4." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K., Konstantinidis K., Klappenbach J., Tiedje J., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MR-4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000446 Genomic DNA. Translation: ABI37678.1.
RefSeq	YP_732735.1. NC_008321.1.
3D structure databases
ProteinModelPortal	Q0HMN9.
SMR	Q0HMN9. Positions 4-67.
ModBase	Search...
Protein-protein interaction databases
STRING	60480.Shewmr4_0598.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABI37678; ABI37678; Shewmr4_0598.
GeneID	4251179.
KEGG	she:Shewmr4_0598.
PATRIC	23577640. VBISheSp133532_0617.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1923.
HOGENOM	HOG000004931.
KO	K03666.
OMA	KNTVTQM.
ProtClustDB	CLSK905837.
Family and domain databases
HAMAP	MF_00436. Lsm_Hfq.
InterPro	IPR005001. Hfq. IPR010920. LSM_dom. IPR001163. Ribonucl_LSM. [Graphical view]
Pfam	PF01423. LSM. 1 hit. [Graphical view]
SUPFAM	SSF50182. Sm_like_riboprot. 1 hit.
TIGRFAMs	TIGR02383. Hfq. 1 hit.
ProtoNet	Search...

Entry information

Entry name

HFQ_SHESM

Accession

Primary (citable) accession number: Q0HMN9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	October 3, 2006
Last modified:	May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program