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Q0HMM4 (Q0HMM4_SHESM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase HAMAP MF_01174
Gene names
Name:astD HAMAP MF_01174
Ordered Locus Names:Shewmr4_0613
OrganismShewanella sp. (strain MR-4) [Complete proteome] [HAMAP] EMBL ABI37693.1
Taxonomic identifier60480 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding220 – 2256NAD By similarity HAMAP MF_01174

Sites

Active site2431 By similarity HAMAP MF_01174
Active site2771 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
Q0HMM4 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: EFAE6C3FBFE07952

FASTA48751,665
        10         20         30         40         50         60 
MTHFIKGQWQ AGKGHDMTSS NPANSEIIWR GQTATAEQVN AAVDAAREAQ FDWFMLGFDA 

        70         80         90        100        110        120 
RLKIVEAYRS QLEANKAELA ETIAQETGKP QWETATEVAA MIGKIGLSAT AYNKRTGTEA 

       130        140        150        160        170        180 
NDTPAGRAVL RHKPHGVVAV FGPYNFPGHL PNGHIVPALL AGNTVVFKPS ELTPKVAELM 

       190        200        210        220        230        240 
VSLWEKAGLP AGVINLVQGE VDTGKALASH PQLDGLFFTG SSRTGHLLHQ QYAGHPGKIL 

       250        260        270        280        290        300 
ALEMGGNNPL IIKGVADIKA AVHDILQSAY ISSGQRCTCA RRLYVEQGEQ GDALVAKLVE 

       310        320        330        340        350        360 
AVKQIKVGPW NAQPQPFMGS MISEGAAKGM VAAQANLQNL GGVSLVELTH LQAGTGLVSP 

       370        380        390        400        410        420 
GLIDVTAVSE LPDEEYFGPL LQLVRYNDFD QAIKLANQTR YGLSAGILAD SRDDYEYFLA 

       430        440        450        460        470        480 
RIRAGIVNWN KQITGASGAA PFGGVGASGN HRASAFYAAD YCAYPVASVE ADAVSLPASL 


SPGLSLE

« Hide

References

[1]"Complete sequence of Shewanella sp. MR-4."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K., Konstantinidis K., Klappenbach J., Tiedje J., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MR-4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000446 Genomic DNA. Translation: ABI37693.1.
RefSeqYP_732750.1. NC_008321.1.

3D structure databases

ProteinModelPortalQ0HMM4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0HMM4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4251194.
GenomeReviewsGene locus Shewmr4_0613 in contig CP000446_GR.
KEGGshe:Shewmr4_0613.
PATRIC23577670. VBISheSp133532_0632.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHBG752218.
OMATHYIAGN.
ProtClustDBPRK09457.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0HMM4_SHESM
AccessionPrimary (citable) accession number: Q0HMM4
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: December 14, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info