ID   CYSC_SHESM              Reviewed;         205 AA.
AC   Q0HFM7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Adenylyl-sulfate kinase;
DE            EC=2.7.1.25;
DE   AltName: Full=APS kinase;
DE   AltName: Full=Adenosine-5'-phosphosulfate kinase;
DE   AltName: Full=ATP adenosine-5'-phosphosulfate 3'-phosphotransferase;
GN   Name=cysC; OrderedLocusNames=Shewmr4_3069;
OS   Shewanella sp. (strain MR-4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=60480;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Nealson K., Konstantinidis K., Klappenbach J.,
RA   Tiedje J., Richardson P.;
RT   "Complete sequence of Shewanella sp. MR-4.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the synthesis of activated sulfate.
CC   -!- CATALYTIC ACTIVITY: ATP + adenylyl sulfate = ADP + 3'-
CC       phosphoadenylyl sulfate.
CC   -!- PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite
CC       from sulfate: step 2/3.
CC   -!- SIMILARITY: Belongs to the APS kinase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000446; ABI40140.1; -; Genomic_DNA.
DR   RefSeq; YP_735197.1; -.
DR   GeneID; 4253640; -.
DR   GenomeReviews; CP000446_GR; Shewmr4_3069.
DR   KEGG; she:Shewmr4_3069; -.
DR   HOGENOM; Q0HFM7; -.
DR   OMA; Q0HFM7; IVWHQHS.
DR   GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0000103; P:sulfate assimilation; IEA:HAMAP.
DR   HAMAP; MF_00065; -; 1.
DR   InterPro; IPR002891; APS_kinase_C.
DR   Pfam; PF01583; APS_kinase; 1.
DR   ProDom; PD002350; APS_kinase; 1.
DR   TIGRFAMs; TIGR00455; apsK; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW   Phosphoprotein; Transferase.
FT   CHAIN         1    205       Adenylyl-sulfate kinase.
FT                                /FTId=PRO_1000009028.
FT   NP_BIND      31     38       ATP (By similarity).
FT   ACT_SITE    105    105       Phosphoserine intermediate (By
FT                                similarity).
SQ   SEQUENCE   205 AA;  22323 MW;  148EEE972C42B378 CRC64;
     MSNIVWHQHS VDQAARAKLK GQNPVLLWFT GLSGAGKSTL AGALERALFE AGFHTYLLDG
     DNVRHGLCKD LGFSVADRDE NLRRVGEVAK LMVDAGLVVL SAFISPTREE RDSIRARFPT
     GQFIEVHVST PLSICEQRDP KGLYVKARRG EISNFTGISS PYEAPLSAEL TIDTSKGDLA
     SQVRALIDYL TAIEVINPSR LTASA
//