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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Shewanella sp. (strain MR-4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:Shewmr4_3496
OrganismiShewanella sp. (strain MR-4)
Taxonomic identifieri60480 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000181191 – 581Arginine--tRNA ligaseAdd BLAST581

Interactioni

Subunit structurei

Monomer.

Structurei

3D structure databases

ProteinModelPortaliQ0HEF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi126 – 136"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.

Phylogenomic databases

HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0HEF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSHIQSLLE QTIESFKQQG ILPADFEARI QVDRTKDKSH GDLATNLAMM
60 70 80 90 100
LTKAAGKNPR ELAQLIIDNL PASAYVAKVE IAGPGFINFF IDDSALANQL
110 120 130 140 150
QAAISDEHLG IKLPTPQTIV VDYSSPNLAK EMHVGHLRST IIGDSVVRTL
160 170 180 190 200
EFLGHKVIRQ NHVGDWGTQF GMLLAYMEEL RAQNGEQAQL ELSDLETFYR
210 220 230 240 250
AAKLRFDESA EFATRARQLV VELQSGDEYC NKLWREFNDI SLSHCHEVYE
260 270 280 290 300
RLGVSLTRAD VHGESAYNAD LEQVVKDLDA QGLLTQSNGA KVVFQEEFRN
310 320 330 340 350
KEGEALPVII QKADGGYLYA TTDLAAMRYR SSVLKADRVL YFVDLRQALH
360 370 380 390 400
FQQVFSLAKL AKFVRNDMSL EHLGFGTMNG EDGRPFKTRT GGVVKLVDLL
410 420 430 440 450
DEANTRALEL VRSKNPDMDE ATLAEIARVV GISAVKYADL SKNRTSDYIF
460 470 480 490 500
SFEQMLSFEG NTAPYLLYAY TRVAGIFKRA TDIDLSQAKI VLEHEKEKDL
510 520 530 540 550
GNKLAQFGEI LSRVIDKGQP HVLCGYLYEL AGAFSSFYEA CPVLAADNDE
560 570 580
QKHSRLLLSQ LTANTLQKGL NLLGIETLER M
Length:581
Mass (Da):64,898
Last modified:October 3, 2006 - v1
Checksum:i154050243DF28005
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000446 Genomic DNA. Translation: ABI40562.1.
RefSeqiWP_011624227.1. NC_008321.1.

Genome annotation databases

EnsemblBacteriaiABI40562; ABI40562; Shewmr4_3496.
KEGGishe:Shewmr4_3496.

Similar proteinsi

Entry informationi

Entry nameiSYR_SHESM
AccessioniPrimary (citable) accession number: Q0HEF5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: November 22, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families