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Protein

Guanylate kinase

Gene

gmk

Organism
Shewanella sp. (strain MR-4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSP60480:G1G76-3788-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Shewmr4_3613
OrganismiShewanella sp. (strain MR-4)
Taxonomic identifieri60480 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663981 – 207Guanylate kinaseAdd BLAST207

Structurei

3D structure databases

ProteinModelPortaliQ0HE40.
SMRiQ0HE40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 184Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037638.
KOiK00942.
OMAiAGNYYGT.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0HE40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTARGNLFIV SAPSGAGKSS LISALLKDKP ADMQVSVSHT TRAPRPGEVN
60 70 80 90 100
GQHYHFVNVE EFKALIEQNA FFEWAEVFGN YYGTSRHVIE HTLTQGIDVF
110 120 130 140 150
LDIDWQGAQQ VKAVMPEAIG VFILPPSRDE LERRLTGRGQ DSQEVIASRM
160 170 180 190 200
AQAVSEMSHY KEYDFIIVND DFDTALADMR AIIRSQRLTG ASQIHAQNDM

LNDLLAG
Length:207
Mass (Da):23,024
Last modified:October 3, 2006 - v1
Checksum:i1D7E427CAE2CEC53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000446 Genomic DNA. Translation: ABI40677.1.
RefSeqiWP_011624338.1. NC_008321.1.

Genome annotation databases

EnsemblBacteriaiABI40677; ABI40677; Shewmr4_3613.
KEGGishe:Shewmr4_3613.

Similar proteinsi

Entry informationi

Entry nameiKGUA_SHESM
AccessioniPrimary (citable) accession number: Q0HE40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 3, 2006
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program