ID   NSP1N_ROTB2             Reviewed;         395 AA.
AC   Q0H8C5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=Non-structural protein 1;
DE            Short=NSP1;
OS   Rotavirus X (isolate RVX/Human/Bangladesh/NADRV-B219/2002/GXP[X]) (RV
OS   ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-B219)).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Sedoreoviridae; Rotavirus.
OX   NCBI_TaxID=348136;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=16900303; DOI=10.1007/s00705-006-0831-y;
RA   Alam M.M., Kobayashi N., Ishino M., Ahmed M.S., Ahmed M.U., Paul S.K.,
RA   Muzumdar B.K., Hussain Z., Wang Y.H., Naik T.N.;
RT   "Genetic analysis of an ADRV-N-like novel rotavirus strain B219 detected in
RT   a sporadic case of adult diarrhea in Bangladesh.";
RL   Arch. Virol. 152:199-208(2007).
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DR   EMBL; DQ168032; ABA60392.1; -; Genomic_RNA.
DR   SMR; Q0H8C5; -.
DR   Proteomes; UP000174021; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00048; DSRM_SF; 1.
DR   Gene3D; 3.30.160.20; -; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   Pfam; PF00035; dsrm; 1.
DR   SMART; SM00358; DSRM; 1.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR   PROSITE; PS50137; DS_RBD; 1.
PE   4: Predicted;
KW   RNA-binding.
FT   CHAIN           1..395
FT                   /note="Non-structural protein 1"
FT                   /id="PRO_0000369858"
FT   DOMAIN          328..395
FT                   /note="DRBM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT   MOTIF           320..327
FT                   /note="Putative autoproteolytic cleavage motif"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   395 AA;  45875 MW;  C30290DE0D877C5E CRC64;
     MMSIQRATQI NRQFDYMSIK ELWMAKFPLH KPGDCLDMFK NGNYTGLTME CIQRTKASKK
     NTIFHIKSDF NSTDYDEPPI SGFKMFTQHC CQRIDEHFCG ALHPVISNIE FEQNQLRTRP
     QVASEFNLFI PCGIKNLKIE SGEDPTWIVG TKFRKCMCLK PVMVAATIIG TPVNKNLITF
     CSSDYIQVIV NRNREGSCGI CMGNTSTYEA CGNWTNETWG EEFSLDLKLC YKCTPVAFIF
     SLMMSTGHKP YVSKRQFEEN RRKWERVLNY KICEENLDSH LACANHENVY KSIKKYEFFD
     SIWVYHLANS SWVRDLTREC IESNPGPNYI QLLNEHSQRY GFIQPTYEII AVVSDGHHSY
     QCTCYYKDTK TQSIGPSKKN AKHQAAEQMF RHQCF
//