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Q0H8C5

- NSP1N_ROTB2

UniProt

Q0H8C5 - NSP1N_ROTB2

Protein

Non-structural protein 1

Gene
N/A
Organism
Rotavirus (isolate Human/Bangladesh/ADRV-N B219/2002) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-B219))
Status
Reviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (03 Oct 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Non-structural protein 1
    Short name:
    NSP1
    OrganismiRotavirus (isolate Human/Bangladesh/ADRV-N B219/2002) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-B219))
    Taxonomic identifieri348136 [NCBI]
    Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirusunclassified rotaviruses
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    ProteomesiUP000008656: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 395395Non-structural protein 1PRO_0000369858Add
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini328 – 39568DRBMPROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi320 – 3278Putative autoproteolytic cleavage motifSequence Analysis

    Sequence similaritiesi

    Contains 1 DRBM (double-stranded RNA-binding) domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    InterProiIPR014720. dsRNA-bd_dom.
    [Graphical view]
    PfamiPF00035. dsrm. 1 hit.
    [Graphical view]
    SMARTiSM00358. DSRM. 1 hit.
    [Graphical view]
    PROSITEiPS50137. DS_RBD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q0H8C5-1 [UniParc]FASTAAdd to Basket

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    MMSIQRATQI NRQFDYMSIK ELWMAKFPLH KPGDCLDMFK NGNYTGLTME    50
    CIQRTKASKK NTIFHIKSDF NSTDYDEPPI SGFKMFTQHC CQRIDEHFCG 100
    ALHPVISNIE FEQNQLRTRP QVASEFNLFI PCGIKNLKIE SGEDPTWIVG 150
    TKFRKCMCLK PVMVAATIIG TPVNKNLITF CSSDYIQVIV NRNREGSCGI 200
    CMGNTSTYEA CGNWTNETWG EEFSLDLKLC YKCTPVAFIF SLMMSTGHKP 250
    YVSKRQFEEN RRKWERVLNY KICEENLDSH LACANHENVY KSIKKYEFFD 300
    SIWVYHLANS SWVRDLTREC IESNPGPNYI QLLNEHSQRY GFIQPTYEII 350
    AVVSDGHHSY QCTCYYKDTK TQSIGPSKKN AKHQAAEQMF RHQCF 395
    Length:395
    Mass (Da):45,875
    Last modified:October 3, 2006 - v1
    Checksum:iC30290DE0D877C5E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ168032 Genomic RNA. Translation: ABA60392.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ168032 Genomic RNA. Translation: ABA60392.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    InterProi IPR014720. dsRNA-bd_dom.
    [Graphical view ]
    Pfami PF00035. dsrm. 1 hit.
    [Graphical view ]
    SMARTi SM00358. DSRM. 1 hit.
    [Graphical view ]
    PROSITEi PS50137. DS_RBD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genetic analysis of an ADRV-N-like novel rotavirus strain B219 detected in a sporadic case of adult diarrhea in Bangladesh."
      Alam M.M., Kobayashi N., Ishino M., Ahmed M.S., Ahmed M.U., Paul S.K., Muzumdar B.K., Hussain Z., Wang Y.H., Naik T.N.
      Arch. Virol. 152:199-208(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiNSP1N_ROTB2
    AccessioniPrimary (citable) accession number: Q0H8C5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: October 3, 2006
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3