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Protein
Submitted name:

DPPY splice variant b

Gene

DPP10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

ESTHERihuman-DPP10. DPP4N_Peptidase_S9.

Names & Taxonomyi

Protein namesi
Submitted name:
DPPY splice variant bImported
Gene namesi
Name:DPP10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 52HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134991647.

PTM / Processingi

Proteomic databases

PaxDbiQ0GLB9.
PeptideAtlasiQ0GLB9.
PRIDEiQ0GLB9.

Expressioni

Gene expression databases

GenevisibleiQ0GLB9. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000376855.

Structurei

3D structure databases

ProteinModelPortaliQ0GLB9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini129 – 495DPPIV_NInterPro annotationAdd BLAST367
Domaini578 – 779Peptidase_S9InterPro annotationAdd BLAST202

Sequence similaritiesi

Belongs to the peptidase S9B family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2100. Eukaryota.
COG1506. LUCA.
HOVERGENiHBG105877.

Family and domain databases

Gene3Di2.140.10.30. 1 hit.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B_N.
[Graphical view]
PfamiPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0GLB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVITEVAEGP VDGSEKELGS NSPPQRNWKG IAIALLVILV VCSLITMSVI
60 70 80 90 100
LLTPDELTNS SETRLSLEDL FRKDFVLHDP EARWINDTDV VYKSENGHVI
110 120 130 140 150
KLNIETNATT LLLENTTFVT FKASRHSVSP DLKYVLLAYD VKQIFHYSYT
160 170 180 190 200
ASYVIYNIHT REVWELNPPE VEDSVLQYAA WGVQGQQLIY IFENNIYYQP
210 220 230 240 250
DIKSSSLRLT SSGKEEIIFN GIADWLYEEE LLHSHIAHWW SPDGERLAFL
260 270 280 290 300
MINDSLVPTM VIPRFTGALY PKGKQYPYPK AGQVNPTIKL YVVNLYGPTH
310 320 330 340 350
TLELMPPDSF KSREYYITMV KWVSNTKTVV RWLNRAQNIS ILTVCETTTG
360 370 380 390 400
ACSKKYEMTS DTWLSQQNEE PVFSRDGSKF FMTVPVKQGG RGEFHHIAMF
410 420 430 440 450
LIQSKSEQIT VRHLTSGNWE VIKILAYDET TQKIYFLSTE SSPRGRQLYS
460 470 480 490 500
ASTEGLLNRQ CISCNFMKEQ CTYFDASFSP MNQHFLLFCE GPRVPVVSLH
510 520 530 540 550
STDNPAKYFI LESNSMLKEA ILKKKIGKPE IKILHIDDYE LPLQLSLPKD
560 570 580 590 600
FMDRNQYALL LIMDEEPGGQ LVTDKFHIDW DSVLIDMDNV IVARFDGRGS
610 620 630 640 650
GFQGLKILQE IHRRLGSVEV KDQITAVKFL LKLPYIDSKR LSIFGKGYGG
660 670 680 690 700
YIASMILKSD EKLFKCGSVV APITDLKLYA SAFSERYLGM PSKEESTYQA
710 720 730 740 750
ASVLHNVHGL KEENILIIHG TADTKVHFQH SAELIKHLIK AGVNYTMQVY
760 770 780 790
PDEGHNVSEK SKYHLYSTIL KFFSDCLKEE ISVLPQEPEE DE
Length:792
Mass (Da):90,324
Last modified:October 3, 2006 - v1
Checksum:iD5E977C5FBBF8355
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ857321 mRNA. Translation: ABI16085.1.
RefSeqiNP_001171508.1. NM_001178037.1.
UniGeneiHs.580539.
Hs.657379.

Genome annotation databases

GeneIDi57628.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ857321 mRNA. Translation: ABI16085.1.
RefSeqiNP_001171508.1. NM_001178037.1.
UniGeneiHs.580539.
Hs.657379.

3D structure databases

ProteinModelPortaliQ0GLB9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000376855.

Protein family/group databases

ESTHERihuman-DPP10. DPP4N_Peptidase_S9.

Proteomic databases

PaxDbiQ0GLB9.
PeptideAtlasiQ0GLB9.
PRIDEiQ0GLB9.

Protocols and materials databases

DNASUi57628.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi57628.

Organism-specific databases

CTDi57628.
PharmGKBiPA134991647.

Phylogenomic databases

eggNOGiKOG2100. Eukaryota.
COG1506. LUCA.
HOVERGENiHBG105877.

Miscellaneous databases

ChiTaRSiDPP10. human.
GenomeRNAii57628.

Gene expression databases

GenevisibleiQ0GLB9. HS.

Family and domain databases

Gene3Di2.140.10.30. 1 hit.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B_N.
[Graphical view]
PfamiPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ0GLB9_HUMAN
AccessioniPrimary (citable) accession number: Q0GLB9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: November 30, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.