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Protein
Submitted name:

Beta-glucosidase

Gene

bgl3B

Organism
Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei58 – 581GlucoseCombined sources
Binding sitei130 – 1301GlucoseCombined sources
Binding sitei210 – 2101GlucoseCombined sources
Binding sitei243 – 2431GlucoseCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Enzyme and pathway databases

BRENDAi3.2.1.21. 6332.

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-glucosidaseImported (EC:3.2.1.21Imported)
Gene namesi
Name:bgl3BImported
OrganismiThermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E)Imported
Taxonomic identifieri309803 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Interactioni

Protein-protein interaction databases

STRINGi309803.CTN_0670.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2X40X-ray2.31A1-721[»]
2X41X-ray2.05A1-721[»]
2X42X-ray2.10A1-721[»]
ProteinModelPortaliQ0GC07.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ0GC07.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni163 – 1642Glucose bindingCombined sources

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1472.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0GC07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKVNEILSQ LTLEEKVKLV VGVGLPGLFG NPHSRVAGAA GETHPVPRVG
60 70 80 90 100
LPAFVLADGP AGLRINPTRE NDENTYYTTA FPVEIMLAST WNRELLEEVG
110 120 130 140 150
KAMGEEVREY GVDVLLAPAM NIHRNPLCGR NFEYYSEDPV LSGEMASSFV
160 170 180 190 200
KGVQSQGVGA CIKHFVANNQ ETNRMVVDTI VSERALREIY LRGFEIAVKK
210 220 230 240 250
SKPWSVMSAY NKLNGKYCSQ NEWLLKKVLR EEWGFEGFVM SDWYAGDNPV
260 270 280 290 300
EQLKAGNDLI MPGKAYQVNT ERRDEIEEIM EALKEGKLSE EVLDECVRNI
310 320 330 340 350
LKVLVNAPSF KNYRYSNKPD LEKHAKVAYE AGAEGVVLLR NEEALPLSEN
360 370 380 390 400
SKIALFGTGQ IETIKGGTGS GDTHPRYAIS ILEGIKERGL NFDEELAKTY
410 420 430 440 450
EDYIKKMRET EEYKPRRDSW GTIIKPKLPE NFLSEKEIHK LAKKNDVAVI
460 470 480 490 500
VISRISGEGY DRKPVKGDFY LSDDETDLIK TVSREFHEQG KKVIVLLNIG
510 520 530 540 550
SPVEVVSWRD LVDGILLVWQ AGQETGRIVA DVLTGRINPS GKLPTTFPRD
560 570 580 590 600
YSDVPSWTFP GEPKDNPQKV VYEEDIYVGY RYYDTFGVEP AYEFGYGLSY
610 620 630 640 650
TTFEYSDLNV SFDGETLRVQ YRIENTGGRA GKEVSQVYIK APKGKIDKPF
660 670 680 690 700
QELKAFHKTR LLNPGESEEV VLEIPVRDLA SFNGEEWVVE AGEYEVRVGA
710 720
SSRNIKLKGT FSVGEERRFK P
Length:721
Mass (Da):81,160
Last modified:October 3, 2006 - v1
Checksum:i78D048F6F9F3AFEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ873691 Genomic DNA. Translation: ABI29899.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ873691 Genomic DNA. Translation: ABI29899.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2X40X-ray2.31A1-721[»]
2X41X-ray2.05A1-721[»]
2X42X-ray2.10A1-721[»]
ProteinModelPortaliQ0GC07.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi309803.CTN_0670.

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiCOG1472.

Enzyme and pathway databases

BRENDAi3.2.1.21. 6332.

Miscellaneous databases

EvolutionaryTraceiQ0GC07.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Subcritical water extraction and beta-glucosidase-catalyzed hydrolysis of quercetin glycosides in onion waste."
    Turner C., Turner P., Jacobson G., Almgren K., Waldeback M., Sjoberg P., Nordberg Karlsson E., Markides K.E.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 4359Imported.
  2. "A novel variant of Thermotoga neapolitana beta-glucosidase B is an efficient catalyst for the synthesis of alkyl glucosides by transglycosylation."
    Turner P., Svensson D., Adlercreutz P., Nordberg Karlsson E.
    J. Biotechnol. 130:67-74(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 4359Imported.
  3. "Structural and functional analyses of beta-glucosidase 3B from Thermotoga neapolitana: a thermostable three-domain representative of glycoside hydrolase 3."
    Pozzo T., Pasten J.L., Karlsson E.N., Logan D.T.
    J. Mol. Biol. 397:724-739(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) IN COMPLEX WITH GLUCOSE.

Entry informationi

Entry nameiQ0GC07_THENN
AccessioniPrimary (citable) accession number: Q0GC07
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: June 24, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.