Reviewed, UniProtKB/Swiss-Prot Q0G9Q7 (NU1C_DAUCA)

Names and origin

Protein names

Recommended name:
    NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic
    EC=1.6.5.-
Alternative name(s):
    NAD(P)H dehydrogenase subunit 1
      Short name=NDH subunit 1
    NADH-plastoquinone oxidoreductase subunit 1

Gene names

Name:

ndhA

Encoded on

Plastid; Chloroplast

Organism

Daucus carota (Carrot)

Taxonomic identifier

4039 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Apiales › Apiaceae › Apioideae › Scandiceae › Daucinae › Daucus

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient By similarity.
Catalytic activity	NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP MF_01350
Subunit structure	NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus By similarity.
Subcellular location	Plastid › chloroplast thylakoid membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the complex I subunit 1 family.

Ontologies

Keywords
Cellular component	Chloroplast Membrane Plastid Thylakoid
Domain	Transmembrane
Ligand	NAD NADP Plastoquinone
Molecular function	Oxidoreductase
PTM	Quinone
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: HAMAP
Cellular component	chloroplast thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 363	363	NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic HAMAP MF_01350		PRO_0000275579
Regions
	Transmembrane	30 – 50	21	Potential
	Transmembrane	98 – 118	21	Potential
	Transmembrane	127 – 147	21	Potential
	Transmembrane	253 – 273	21	Potential
	Transmembrane	300 – 320	21	Potential
	Transmembrane	336 – 356	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q0G9Q7-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 92C4B4720A5ED7E0	FASTA	363	40,228
	10 20 30 40 50 60 MIIDTTEVQA INSFFRLESL KEVYDIIWML VPILTLVLGI TIGVLVIVWL EREISAGIQQ 70 80 90 100 110 120 RIGPEYAGPL GILQALADGT KLLFKENLLP SRGDTRLFSI GPSIAVTSIL LSYLVIPFGY 130 140 150 160 170 180 RLVLADVSIG VFLWIAISSI APVGLLMSGY GSNNKYSFLG GLRAAAQSIS YEIPLTLCVL 190 200 210 220 230 240 SISLLSNSSS TVDIVEAQSK YGFWGWNLWR QPIGFIVFLI SSLAECERLP FDLPEAEEEL 250 260 270 280 290 300 VAGYQTEYSG IKFGLFYVAS YLNLLVSSLF VTVLYLGGWN LSLPHIALPF FFEINKAGRV 310 320 330 340 350 360 FGTIIGIFIT LAKTYLFLFI AITTRWTLPR LRMDQLLNLG WKFLLPISLG NLLLTTSSQL LSL

References

[1]

"Complete plastid genome sequence of Daucus carota: implications for biotechnology and phylogeny of angiosperms." Ruhlman T., Lee S.-B., Jansen R.K., Hostetler J.B., Tallon L.J., Town C.D., Daniell H. BMC Genomics 7:222-222(2006) [PubMed: 16945140] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Danvers Half-long.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ898156 Genomic DNA. Translation: ABI32479.1.
RefSeq	YP_740172.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4266815.
Family and domain databases
HAMAP	MF_01350. [Tree]
InterPro	IPR001694. NADH_UbQ_OxRdtase_su1. IPR018086. NADH_UbQ_OxRdtase_su1_CS. [Graphical view]
PANTHER	PTHR11432. Resp_NADH_DH_1. 1 hit.
Pfam	PF00146. NADHdh. 1 hit. [Graphical view]
PROSITE	PS00667. COMPLEX1_ND1_1. 1 hit. PS00668. COMPLEX1_ND1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NU1C_DAUCA

Accession

Primary (citable) accession number: Q0G9Q7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	October 3, 2006
Last modified:	June 16, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)