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Q0EFB4

- Q0EFB4_HUMAN

UniProt

Q0EFB4 - Q0EFB4_HUMAN

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Protein
Submitted name:

MICB antigen

Gene

MICB

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. antigen processing and presentation Source: InterPro
  2. immune response Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MICB antigenImported
Submitted name:
MICB proteinImported
Gene namesi
Name:MICBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliQ0EFB4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG106364.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q0EFB4-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
PHSLRYNLMV LSQDGSVQSG FLAEGHLDGQ PFLRYDRQKR RAKPQGQWAE
60 70 80 90 100
DVLGAKTWDT ETEDLTENGQ DLRRTLTHIK DQKGGLHSLQ EIRVCEIHED
110 120 130 140 150
SSTRGSRHFY YDGELFLSQN LETQESTVPQ SSRAQTLAMN VTNFWKEDAM
160 170 180 190 200
KTKTHYRAMQ ADCLQKLQRY LKSGVAIRRT VPPMVNVTCS EVSEGNITVT
210 220 230 240 250
CRASSFYPRN ITLTWRQDGV SLSHNTQQWG DVLPDGNGTY QTWVATRIRQ
260 270 280 290 300
GEEQRFTCYM EHSGNHGTHP VPSGKALVLQ SQRTDFPYVS AAMPCFVIII
310 320 330 340 350
ILCVPCCKKK TSAAEGPELV SLQVLDQHPV GTGDHRDAAQ LGFQPLMSAT

GSTGSTEGA
Length:359
Mass (Da):40,134
Last modified:October 17, 2006 - v1
Checksum:i61E437F858C08985
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JX282181 Genomic DNA. Translation: AFR77728.1.
JX282182 Genomic DNA. Translation: AFR77729.1.
JX282184 Genomic DNA. Translation: AFR77731.1.
AB103613 Genomic DNA. Translation: BAF31274.1.
UniGeneiHs.731446.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JX282181 Genomic DNA. Translation: AFR77728.1 .
JX282182 Genomic DNA. Translation: AFR77729.1 .
JX282184 Genomic DNA. Translation: AFR77731.1 .
AB103613 Genomic DNA. Translation: BAF31274.1 .
UniGenei Hs.731446.

3D structure databases

ProteinModelPortali Q0EFB4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

H-InvDB HIX0025017.
HIX0166131.
HIX0166668.

Phylogenomic databases

HOVERGENi HBG106364.

Miscellaneous databases

ChiTaRSi MICB. human.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view ]
SMARTi SM00407. IGc1. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity."
    Shiina T., Ota M., Shimizu S., Katsuyama Y., Hashimoto N., Takasu M., Anzai T., Kulski J.K., Kikkawa E., Naruse T., Kimura N., Yanagiya K., Watanabe A., Hosomichi K., Kohara S., Iwamoto C., Umehara Y., Meyer A.
    , Wanner V., Sano K., Macquin C., Ikeo K., Tokunaga K., Gojobori T., Inoko H., Bahram S.
    Genetics 173:1555-1570(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Zhu F.M., Ying Y.L., He Y.M.
    Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Distribution of MICB diversity in the Zhejiang Han population: PCR sequence-based typing for exons 2-6 and identification of five novel MICB alleles."
    Ying Y., He Y., Tao S., Han Z., Wang W., Chen N., He J., Zhang W., He J., Zhu F., Lv H.
    Immunogenetics 65:485-492(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ0EFB4_HUMAN
AccessioniPrimary (citable) accession number: Q0EFB4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.