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Q0EFB4

- Q0EFB4_HUMAN

UniProt

Q0EFB4 - Q0EFB4_HUMAN

Protein
Submitted name:

MICB antigen

Gene

MICB

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (17 Oct 2006)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. antigen processing and presentation Source: InterPro
    2. immune response Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MICB antigenImported
    Submitted name:
    MICB proteinImported
    Gene namesi
    Name:MICBImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliQ0EFB4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG106364.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view]
    SMARTiSM00407. IGc1. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.
    PROSITEiPS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q0EFB4-1 [UniParc]FASTAAdd to Basket

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    PHSLRYNLMV LSQDGSVQSG FLAEGHLDGQ PFLRYDRQKR RAKPQGQWAE    50
    DVLGAKTWDT ETEDLTENGQ DLRRTLTHIK DQKGGLHSLQ EIRVCEIHED 100
    SSTRGSRHFY YDGELFLSQN LETQESTVPQ SSRAQTLAMN VTNFWKEDAM 150
    KTKTHYRAMQ ADCLQKLQRY LKSGVAIRRT VPPMVNVTCS EVSEGNITVT 200
    CRASSFYPRN ITLTWRQDGV SLSHNTQQWG DVLPDGNGTY QTWVATRIRQ 250
    GEEQRFTCYM EHSGNHGTHP VPSGKALVLQ SQRTDFPYVS AAMPCFVIII 300
    ILCVPCCKKK TSAAEGPELV SLQVLDQHPV GTGDHRDAAQ LGFQPLMSAT 350
    GSTGSTEGA 359
    Length:359
    Mass (Da):40,134
    Last modified:October 17, 2006 - v1
    Checksum:i61E437F858C08985
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JX282181 Genomic DNA. Translation: AFR77728.1.
    JX282182 Genomic DNA. Translation: AFR77729.1.
    JX282184 Genomic DNA. Translation: AFR77731.1.
    AB103613 Genomic DNA. Translation: BAF31274.1.
    UniGeneiHs.731446.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JX282181 Genomic DNA. Translation: AFR77728.1 .
    JX282182 Genomic DNA. Translation: AFR77729.1 .
    JX282184 Genomic DNA. Translation: AFR77731.1 .
    AB103613 Genomic DNA. Translation: BAF31274.1 .
    UniGenei Hs.731446.

    3D structure databases

    ProteinModelPortali Q0EFB4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    H-InvDB HIX0025017.
    HIX0166131.
    HIX0166668.

    Phylogenomic databases

    HOVERGENi HBG106364.

    Miscellaneous databases

    ChiTaRSi MICB. human.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view ]
    SMARTi SM00407. IGc1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    PROSITEi PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity."
      Shiina T., Ota M., Shimizu S., Katsuyama Y., Hashimoto N., Takasu M., Anzai T., Kulski J.K., Kikkawa E., Naruse T., Kimura N., Yanagiya K., Watanabe A., Hosomichi K., Kohara S., Iwamoto C., Umehara Y., Meyer A.
      , Wanner V., Sano K., Macquin C., Ikeo K., Tokunaga K., Gojobori T., Inoko H., Bahram S.
      Genetics 173:1555-1570(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. Zhu F.M., Ying Y.L., He Y.M.
      Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. "Distribution of MICB diversity in the Zhejiang Han population: PCR sequence-based typing for exons 2-6 and identification of five novel MICB alleles."
      Ying Y., He Y., Tao S., Han Z., Wang W., Chen N., He J., Zhang W., He J., Zhu F., Lv H.
      Immunogenetics 65:485-492(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ0EFB4_HUMAN
    AccessioniPrimary (citable) accession number: Q0EFB4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 17, 2006
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.