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Q0E8J6

- Q0E8J6_DROME

UniProt

Q0E8J6 - Q0E8J6_DROME

Protein
Submitted name:

CG33791, isoform A

Gene

CG33791

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (17 Oct 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
    2. thiamine pyrophosphate binding Source: InterPro

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CG33791, isoform AImported (EC:1.2.4.2Imported)
    Submitted name:
    CG33791, isoform CImported (EC:1.2.4.2Imported)
    Gene namesi
    ORF Names:CG33791Imported, Dmel_CG33791Imported
    OrganismiDrosophila melanogaster (Fruit fly)Imported
    Taxonomic identifieri7227 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000803: Chromosome 3L

    Organism-specific databases

    FlyBaseiFBgn0035240. CG33791.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000063092.
    InParanoidiQ0E8J6.
    KOiK00164.

    Family and domain databases

    Gene3Di3.40.50.970. 2 hits.
    InterProiIPR011603. 2oxoglutarate_DH_E1.
    IPR001017. DH_E1.
    IPR029061. THDP-binding.
    IPR005475. Transketolase-like_Pyr-bd.
    [Graphical view]
    PANTHERiPTHR23152. PTHR23152. 1 hit.
    PfamiPF00676. E1_dh. 1 hit.
    PF02779. Transket_pyr. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
    SMARTiSM00861. Transket_pyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF52518. SSF52518. 2 hits.
    TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0E8J6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNQCRLRSLA RIRRSLTLGL RGTDQHVLAR QALRTIQTTS QRRGVHDLDS     50
    FANGCSAAYI EGLYNKWKRN PSSVDESWNE LFSSNDWSSP KRSPLQVSHS 100
    RKYRRPPVER IAVKARSGER TASGGASAAP AAPPSDWKNI DDHHVIQAII 150
    RAYQSRGHLA ADLDPLGIVG PKKRTSVDGT QRHAAREVLR QHFSYIFNDL 200
    NTVFKLPSST MIGGDQEFLS LKEILDRLER IYCGHIGVEY MQITSLTKTN 250
    WLRDRFEKPG GLDLTKEEKK LILERLTRST GFENFLAKKF SSEKRFGLEG 300
    CDIMIPAIKE VVDRATDHGV ESILIGMAHR GRLNVLANIC RKPISDILSQ 350
    FHGLQATDSG SGDVKYHLGV FQERLNRQTN RMVRITVVAN PSHLEHVNPV 400
    LLGKARAEMF QRGDTCGSTV MPIIIHGDAS FSGQGVVYES MHLSDLPNYT 450
    TYGTIHIVSN NQVGFTTDPR FSRSSRYCTD VAKVVNAPIL HVNADDPEAC 500
    IQCARIAIDY RTRFKKDVVI DIVGYRRNGH NEADEPMFTQ PLMYQRIKKL 550
    KPCLQLYADK LIKEGVVTDS EFKAMVSSYE KICEDAWAKS KTIKTIKYSS 600
    WIDSPWPGFF EGRDRLKLCP TGISTDTLKT IGNMFSTPPP PEHKFETHKG 650
    ILRILAQRTQ MVQDKVADWS LGEAFAFGSL LKEGIHVRLS GQDVERGTFS 700
    HRHHVLHHQS EDKVVYNSLD HLYPDQAPYS VSNSSLSECA VLGFEHGYSM 750
    ASPNALVMWE GQFGDFCNTA QCIIDTFIAS GETKWVRQSG VVMLLPHSME 800
    GMGPEHSSGR IERFLQMSDD DPDVYPDTCD ADFVARQLMN VNWIVTNLST 850
    PANLFHCLRR QVKMGFRKPL INFSPKSLLR HPLARSPFKD FNECSCFQRI 900
    IPDKGPAGKQ PDCVQKLVFC SGKVYYDLVK ERDDHEQVET VALVRVEQLC 950
    PFPYDLISQQ LELYPKAELL WAQEEHKNMG AWSYVQPRFD TALLKNENES 1000
    RCVSYHGRPP SASPATGNKV QHYNEYKALI TSIFGELTPE NKKRIEDRIK 1050
    KQQAKAKADA QSKPSTKPPA APPKGGSSPP PGPAPRKPLI SLPSRPPRGG 1100
    KQRSGSAPAP NLVDEDSAAR NREPDASAYD GASPSAWKRS GSAPAPSVVP 1150
    RASASRSPSR KSPSPSHDGI SPSTRQESLS KKKSGSAPAP TPTSRGPFRT 1200
    APSNTEFIKR RPAKDYGSRN ETQSTPGESE LDPTKPQP 1238
    Length:1,238
    Mass (Da):138,230
    Last modified:October 17, 2006 - v1
    Checksum:i8343393BAD0F1002
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014296 Genomic DNA. Translation: AAN11492.1.
    AE014296 Genomic DNA. Translation: AAO41213.1.
    RefSeqiNP_001027099.1. NM_001031928.2.
    NP_001027101.1. NM_001031930.2.
    UniGeneiDm.4028.

    Genome annotation databases

    EnsemblMetazoaiFBtr0091792; FBpp0072635; FBgn0035240.
    FBtr0091794; FBpp0072633; FBgn0035240.
    GeneIDi317974.
    KEGGidme:Dmel_CG33791.
    UCSCiCG33791-RA. d. melanogaster.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014296 Genomic DNA. Translation: AAN11492.1 .
    AE014296 Genomic DNA. Translation: AAO41213.1 .
    RefSeqi NP_001027099.1. NM_001031928.2.
    NP_001027101.1. NM_001031930.2.
    UniGenei Dm.4028.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0091792 ; FBpp0072635 ; FBgn0035240 .
    FBtr0091794 ; FBpp0072633 ; FBgn0035240 .
    GeneIDi 317974.
    KEGGi dme:Dmel_CG33791.
    UCSCi CG33791-RA. d. melanogaster.

    Organism-specific databases

    FlyBasei FBgn0035240. CG33791.

    Phylogenomic databases

    GeneTreei ENSGT00530000063092.
    InParanoidi Q0E8J6.
    KOi K00164.

    Miscellaneous databases

    GenomeRNAii 317974.
    NextBioi 844397.

    Family and domain databases

    Gene3Di 3.40.50.970. 2 hits.
    InterProi IPR011603. 2oxoglutarate_DH_E1.
    IPR001017. DH_E1.
    IPR029061. THDP-binding.
    IPR005475. Transketolase-like_Pyr-bd.
    [Graphical view ]
    PANTHERi PTHR23152. PTHR23152. 1 hit.
    Pfami PF00676. E1_dh. 1 hit.
    PF02779. Transket_pyr. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
    SMARTi SM00861. Transket_pyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52518. SSF52518. 2 hits.
    TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Drosophila melanogaster."
      Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
      , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
      Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    3. Cited for: GENOME REANNOTATION.
      Strain: BerkeleyImported.
    4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
      Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
      Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
      Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
      Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    6. "Combined evidence annotation of transposable elements in genome sequences."
      Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
      PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    7. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
      Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    8. "Drosophila melanogaster release 4 sequence."
      Berkeley Drosophila Genome Project
      Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
      Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    9. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
      Smith C.D., Shu S., Mungall C.J., Karpen G.H.
      Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    11. FlyBase
      Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ0E8J6_DROME
    AccessioniPrimary (citable) accession number: Q0E8J6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 17, 2006
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3