Q0E8E8 (Q0E8E8_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
MIP08013p1 EMBL AEN71953.1

Submitted name:
Mitochondrial phosphate carrier protein, isoform A EMBL AAF49735.1
Submitted name:
Mitochondrial phosphate carrier protein, isoform B EMBL AAF49734.1

Gene names

Name:	Mpcp FlyBase FBgn0026409 EMBL AAF49734.1
Synonyms:	Mpcp-RA EMBL AEN71953.1
ORF Names:	Dmel_CG4994 EMBL AAF49735.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	356 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the mitochondrial carrier family. RuleBase RU000488

Ontologies

Keywords
Biological process	Transport RuleBase RU000488
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS023395
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW wing disc dorsal/ventral pattern formation Inferred from genetic interaction. Source: FlyBase
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0E8E8 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: ECEF634CC766342A	FASTA	356	38,850
	10 20 30 40 50 60 MFSSFFETAR NSPFRTPMSM ARCDAAAPVV EPQPVEGRQI AAAATPVANQ QDSCEFGSTK 70 80 90 100 110 120 YFALCGIGGI LSCGTTHTFV VPLDLVKCRL QVDQAKYKNL VHGFKVTVAE EGARGLAKGW 130 140 150 160 170 180 FPTLLGYSAQ GLCKFGLYEL FKVKYAEIIG EENAYLYRTS LYLAASASAE FFADIALAPF 190 200 210 220 230 240 EAAKVKIQTI PGYANNFREA VPKMLKEEGV NAFYKGLVPL WMRQIPYTMM KFACFERTVE 250 260 270 280 290 300 LLYKYVVPKP RADCTKGEQL IVTFAAGYIA GVFCAVVSHP ADVVVSKLNQ AKGASAISVA 310 320 330 340 350 KSLGFSGMWN GLTPRIIMIG TLTALQWFIY DGVKVALGIP RPPPPEMPAS LKAKQH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Release 5.1 annotation of Drosophila melanogaster heterochromatin." Smith C.D., Shu S., Mungall C.J., Karpen G.H. Science 316:1586-1591(2007) [PubMed: 17569856] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Sequence finishing and mapping of Drosophila melanogaster heterochromatin." Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., Dimitri P., Karpen G.H., Celniker S.E. Science 316:1625-1628(2007) [PubMed: 17569867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[4]	"Combined evidence annotation of transposable elements in genome sequences." Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D. PLoS Comput. Biol. 1:166-175(2005) [PubMed: 16110336] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[5]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[6]	"Heterochromatic sequences in a Drosophila whole-genome shotgun assembly." Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H. Genome Biol. 3:RESEARCH0085.1-RESEARCH0085.16(2002) [PubMed: 12537574] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[7]	"The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective." Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J.W., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E. Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed: 12537573] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[8]	"Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence." Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., Pacleb J.M., Park S. , Pfeiffer B.D., Richards S., Sodergren E.J., Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M. Genome Biol. 3 (12), RESEARCH0079 (2002) Cited for: NUCLEOTIDE SEQUENCE.
[9]	Drosophila Heterochromatin Genome Project Smith C.D., Shu S., Mungall C.J., Karpen G.H. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[10]	FlyBase Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[11]	Carlson J., Booth B., Frise E., Sandler J., Wan K., Yu C., Celniker S. Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[12]	Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Karpen G. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[13]	Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[14]	"Drosophila melanogaster release 4 sequence." Berkeley Drosophila Genome Project Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014296 Genomic DNA. Translation: AAF49734.1. AE014296 Genomic DNA. Translation: AAF49735.1. BT128860 mRNA. Translation: AEN71953.1.
RefSeq	NP_524069.2. NM_079345.2. NP_729978.1. NM_168588.1.
UniGene	Dm.6838.
3D structure databases
ProteinModelPortal	Q0E8E8.
SMR	Q0E8E8. Positions 67-246.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q0E8E8. 2 interactions.
STRING	Q0E8E8.
Proteomic databases
PRIDE	Q0E8E8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0075718; FBpp0075461; FBgn0026409. FBtr0075719; FBpp0075462; FBgn0026409. FBtr0308595; FBpp0300819; FBgn0026409.
GeneID	39587.
KEGG	dme:Dmel_CG4994.
UCSC	CG4994-RA. d. melanogaster.
Organism-specific databases
CTD	39587.
FlyBase	FBgn0026409. Mpcp.
Phylogenomic databases
InParanoid	Q0E8E8.
OMA	SLGFMGM.
OrthoDB	EOG42V6XS.
PhylomeDB	Q0E8E8.
Gene expression databases
ArrayExpress	Q0E8E8.
Bgee	Q0E8E8.
Family and domain databases
InterPro	IPR018108. Mitochondrial_sb/sol_carrier. IPR023395. Mt_carrier_dom. [Graphical view]
Gene3D	G3DSA:1.50.40.10. G3DSA:1.50.40.10. 1 hit.
KO	K15102.
Pfam	PF00153. Mito_carr. 3 hits. [Graphical view]
SUPFAM	SSF103506. Mitoch_carrier. 1 hit.
PROSITE	PS50920. SOLCAR. 3 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	814406.

Entry information

Entry name

Q0E8E8_DROME

Accession

Primary (citable) accession number: Q0E8E8

Entry history

Integrated into UniProtKB/TrEMBL:	October 17, 2006
Last sequence update:	October 17, 2006
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)