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Q0E459 (MPK13_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitogen-activated protein kinase 13

Short name=MAP kinase 13
EC=2.7.11.24
Alternative name(s):
Benzothiadiazole-induced MAP kinase 2
MAP kinase 2
OsBIMK2
OsBWMK2
OsMAPK2
OsMPK17-2
Wound- and blast-induced MAPK 2
Gene names
Name:MPK13
Synonyms:BIMK2, BWMK2, MAPK2, MPK17-2
Ordered Locus Names:Os02g0135200, LOC_Os02g04230
ORF Names:P0585B01.25
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length506 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulation

Activated by threonine and tyrosine phosphorylation By similarity.

Induction

By salicylic acid (SA), ethylene and infection with rice blast fungus (M.grisea). Ref.5

Domain

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Post-translational modification

Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Contains 1 protein kinase domain.

Sequence caution

The sequence AAF23903.1 differs from that shown. Reason: Frameshift at several positions.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 506506Mitogen-activated protein kinase 13
PRO_0000239756

Regions

Domain13 – 304292Protein kinase
Nucleotide binding19 – 279ATP By similarity
Motif175 – 1773TXY

Sites

Active site1391Proton acceptor By similarity
Binding site421ATP By similarity

Amino acid modifications

Modified residue1751Phosphothreonine By similarity
Modified residue1771Phosphotyrosine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0E459 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 7EBCBA768079F972

FASTA50658,281
        10         20         30         40         50         60 
MEFFTEYGEA SQYQIQEVVG KGSYGVVAAA VDTHTGERVA IKKINDVFEH VSDAIRILRE 

        70         80         90        100        110        120 
IKVLRLLRHP DIVVIKHIML PPTRREFRDI YVVFELMESD LHQVIEANHD LSPEHHRFFL 

       130        140        150        160        170        180 
YQLLCALKYI HSANVFHRDL KPKNILANSD CKLKICDFGL ARVAFNDSPS TIFWTDYVAT 

       190        200        210        220        230        240 
RWYRAPELCG SFFSKYTPAI DIWSIGCIFA EILTGRPLFP GRNVVHQLDL ITDLLGTPSS 

       250        260        270        280        290        300 
ETLSRIRNEN ARGYLTGMQR KHPIPFSHKF HNADPLALRL LERLLAFDPK DRPTAEEALA 

       310        320        330        340        350        360 
DPYFRGISKL SREPSRLPVS KFEFEFERRK LTKDDVREMI YREILEYHPQ MLQEYIRGGE 

       370        380        390        400        410        420 
QISFLYPSGV DRFKRQFAHL EENYSRGERS TPLRRQHASL PRERVCSSVD SNNQDSDNEE 

       430        440        450        460        470        480 
RRAISSIART MISPPRSQEK GKNRASAYPN GIINLNSNPK IYLKSASISA STCIIRGNKG 

       490        500 
PKENGISEDM EEVVYELSDN VTRMLS 

« Hide

References

« Hide 'large scale' references
[1]"Novel plant MAP kinases phosphorylate defense-related transcription factors."
Cheong Y.H., Moon B.C., Kim J.K., Cho M.J.
Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Oryza sativa (japonica cultivar-group) wound and blast induced MAPK (BWMK2) mRNA."
Wang D.-P., Zhao W.-S., Wang M., Meng X.-B., Lin R.-M., Zhang S.-H., Peng Y.-L.
Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Aichiasahi.
[3]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[4]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[5]"Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
Reyna N.S., Yang Y.
Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF194416 mRNA. Translation: AAF23903.1. Frameshift.
AY588939 mRNA. Translation: AAT00625.1.
AP004799 Genomic DNA. Translation: BAD10093.1.
AP008208 Genomic DNA. Translation: BAF07729.1.
RefSeqNP_001045815.1. NM_001052350.1.
UniGeneOs.2356.

3D structure databases

ProteinModelPortalQ0E459.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ0E459.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4328223.
KEGGosa:4328223.

Organism-specific databases

GrameneQ0E459.

Phylogenomic databases

eggNOGCOG0515.
OMANMRKKPP.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMPK13_ORYSJ
AccessionPrimary (citable) accession number: Q0E459
Secondary accession number(s): Q6QUV9, Q6Z831, Q9SE22
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 17, 2006
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations