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Q0E2S4

- PP2A3_ORYSJ

UniProt

Q0E2S4 - PP2A3_ORYSJ

Protein

Serine/threonine-protein phosphatase PP2A-3 catalytic subunit

Gene

PP2A3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (17 Oct 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi55 – 551Manganese 1By similarity
    Metal bindingi57 – 571Manganese 1By similarity
    Metal bindingi83 – 831Manganese 1By similarity
    Metal bindingi83 – 831Manganese 2By similarity
    Metal bindingi115 – 1151Manganese 2By similarity
    Active sitei116 – 1161Proton donorBy similarity
    Metal bindingi165 – 1651Manganese 2By similarity
    Metal bindingi239 – 2391Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    GO - Biological processi

    1. cellular protein localization Source: EnsemblPlants/Gramene
    2. chloroplast avoidance movement Source: EnsemblPlants/Gramene
    3. protein dephosphorylation Source: EnsemblPlants/Gramene
    4. regulation of auxin polar transport Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphatase PP2A-3 catalytic subunit (EC:3.1.3.16)
    Gene namesi
    Name:PP2A3
    Ordered Locus Names:Os02g0217600, LOC_Os02g12580
    ORF Names:OsJ_005728, P0027A02.2-1, P0027A02.2-2
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 2

    Organism-specific databases

    GrameneiQ0E2S4.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytosol Source: EnsemblPlants/Gramene
    2. nucleus Source: EnsemblPlants/Gramene
    3. plasma membrane Source: EnsemblPlants/Gramene

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 307307Serine/threonine-protein phosphatase PP2A-3 catalytic subunitPRO_0000058863Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    IntActiQ0E2S4. 2 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0E2S4.
    SMRiQ0E2S4. Positions 7-307.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PPP phosphatase family. PP-2A subfamily.Curated

    Phylogenomic databases

    eggNOGiCOG0639.
    KOiK04382.
    OMAiVEPETTR.

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q0E2S4-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MPSSHGDLDR QIAQLRECKH LAEGEVRALC EQAKAILMEE WNVQPVRCPV    50
    TVCGDIHGQF YDLIELFRIG GEAPDTNYLF MGDYVDRGYY SVETVSLLVA 100
    LKVRYRDRIT ILRGNHESRQ ITQVYGFYDE CLRKYGNANV WKYFTDLFDY 150
    LPLTALIENQ VFCLHGGLSP SLDTLDNIRA LDRIQEVPHE GPMCDLLWSD 200
    PDDRCGWGIS PRGAGYTFGQ DIAQQFNHTN GLSLISRAHQ LVMEGFNWCQ 250
    DKNVVTVFSA PNYCYRCGNM AAILEIGENM DQNFLQFDPA PRQIEPDTTR 300
    KTPDYFL 307
    Length:307
    Mass (Da):35,145
    Last modified:October 17, 2006 - v1
    Checksum:i97143563695D0DD6
    GO
    Isoform 2 (identifier: Q0E2S4-2) [UniParc] [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         68-80: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:294
    Mass (Da):33,710
    Checksum:iCDB4E67BCE48D047
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei68 – 8013Missing in isoform 2. 1 PublicationVSP_019124Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004996 Genomic DNA. Translation: BAD17174.1.
    AP004996 Genomic DNA. Translation: BAD17175.1.
    AP008208 Genomic DNA. Translation: BAF08214.1.
    CM000139 Genomic DNA. No translation available.
    AK060905 mRNA. No translation available.
    AK072676 mRNA. No translation available.
    RefSeqiNP_001046300.1. NM_001052835.1. [Q0E2S4-1]
    UniGeneiOs.10337.

    Genome annotation databases

    EnsemblPlantsiOS02T0217600-02; OS02T0217600-02; OS02G0217600. [Q0E2S4-1]
    GeneIDi4328734.
    KEGGiosa:4328734.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004996 Genomic DNA. Translation: BAD17174.1 .
    AP004996 Genomic DNA. Translation: BAD17175.1 .
    AP008208 Genomic DNA. Translation: BAF08214.1 .
    CM000139 Genomic DNA. No translation available.
    AK060905 mRNA. No translation available.
    AK072676 mRNA. No translation available.
    RefSeqi NP_001046300.1. NM_001052835.1. [Q0E2S4-1 ]
    UniGenei Os.10337.

    3D structure databases

    ProteinModelPortali Q0E2S4.
    SMRi Q0E2S4. Positions 7-307.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q0E2S4. 2 interactions.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS02T0217600-02 ; OS02T0217600-02 ; OS02G0217600 . [Q0E2S4-1 ]
    GeneIDi 4328734.
    KEGGi osa:4328734.

    Organism-specific databases

    Gramenei Q0E2S4.

    Phylogenomic databases

    eggNOGi COG0639.
    KOi K04382.
    OMAi VEPETTR.

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    3. "The genomes of Oryza sativa: a history of duplications."
      Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
      , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
      PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiPP2A3_ORYSJ
    AccessioniPrimary (citable) accession number: Q0E2S4
    Secondary accession number(s): Q6Z6L8, Q6Z6L9, Q9XGT7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3