Q0DV32 (4CLL1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
4-coumarate--CoA ligase-like 1
EC=6.2.1.-

Gene names

Name:	4CLL1
Ordered Locus Names:	Os03g0152400, LOC_Os03g05780

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	552 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Domain	Both substrate-binding domains (SBD1 and SBD2) are involved in the substrate recognition, and are sufficient to confer the substrate specificity.
Sequence similarities	Belongs to the ATP-dependent AMP-binding enzyme family.
Sequence caution	The sequence BAF10906.2 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 552	552	4-coumarate--CoA ligase-like 1		PRO_0000351627
Regions
	Nucleotide binding	205 – 213	9	ATP By similarity
	Nucleotide binding	346 – 351	6	ATP By similarity
	Region	276 – 345	70	SBD1
	Region	346 – 411	66	SBD2
Sites
	Binding site	431	1	ATP By similarity
	Binding site	446	1	ATP By similarity
	Binding site	537	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0DV32 [UniParc]. Last modified October 14, 2008. Version 2. Checksum: 07ED8ED4D98494C1	FASTA	552	58,971
	10 20 30 40 50 60 MASASVPAAG YGADGVYRSL RPPAPVASDP GLSLTDLLLR RADACPSAVA LADAAAGGRA 70 80 90 100 110 120 LTFAELRSAV LSTAVALSSR AGVRPGDAVL LLAPNCVLYP VCFFAVTALG AVGTTVNPDY 130 140 150 160 170 180 TPREIAKQVS DARAKLVITI SALVPKIAGL RLPVILLDDD ANAAAASLPP DATVTLYTNL 190 200 210 220 230 240 VAGVKEADYR RPPIKQSDTA ALLYSSGTTG DSKGVILTHR NFIAAARMVT SDQDERREGP 250 260 270 280 290 300 NVFLCFLPMF HIFGLSVITY AQLHRGNAII AMSRFDINSL MEAVQRHRVT HLFCVPPVII 310 320 330 340 350 360 ALAKHGKAGK YDLSSLKFIG SGAAPLGKDV MEVVAKKFPD SEIVQGYGMT ETCGIISLEY 370 380 390 400 410 420 PEKGQAREFG STGTLVSGVE AKIVDIKTLK HLPPNQVGEI CVRGPNVMQG YFNNVQATEF 430 440 450 460 470 480 TIKQGWLHTG DLGYFDGGGQ LFVVDRLKEL IKYKGFQIAP AELEGLLLSH PEILDAVVIP 490 500 510 520 530 540 FPDAKAGEVP IAYVVRSPDS SLTEVDVQKF IEKQVAYYKR LKRVTFVGSV PKSASGKILR 550 RQLIAQVRSS KL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed: 18089549] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Oryza sativa full length cDNA." The rice full-length cDNA consortium Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella." de Azevedo Souza C., Barbazuk B., Ralph S.G., Bohlmann J., Hamberger B., Douglas C.J. New Phytol. 179:987-1003(2008) [PubMed: 18627494] [Abstract] Cited for: GENE FAMILY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DP000009 Genomic DNA. Translation: ABF94022.1. AP008209 Genomic DNA. Translation: BAF10906.2. Sequence problems. AK242087 mRNA. No translation available.
RefSeq	NP_001048992.2. NM_001055527.2.
UniGene	Os.11459.
3D structure databases
ProteinModelPortal	Q0DV32.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os03g05780.1; LOC_Os03g05780.1; LOC_Os03g05780.
GeneID	4331650.
KEGG	osa:4331650.
Phylogenomic databases
GeneTree	EPGT00070000028073.
OMA	ADACPSA.
PhylomeDB	Q0DV32.
ProtClustDB	CLSN2919294.
Family and domain databases
InterPro	IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. [Graphical view]
KO	K01904.
Pfam	PF00501. AMP-binding. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

4CLL1_ORYSJ

Accession

Primary (citable) accession number: Q0DV32
Secondary accession number(s): Q10RN5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 14, 2008
Last sequence update:	October 14, 2008
Last modified:	December 14, 2011
This is version 38 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program