ID   BGL19_ORYSJ             Reviewed;         528 AA.
AC   Q0DIT2; A0A0N7KKM6; Q60DY5; Q75IT1;
DT   15-DEC-2009, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   RecName: Full=Beta-glucosidase 19;
DE            Short=Os5bglu19;
DE            EC=3.2.1.21 {ECO:0000250|UniProtKB:Q75I94};
DE   Flags: Precursor;
GN   Name=BGLU19; OrderedLocusNames=Os05g0365600, LOC_Os05g30250;
GN   ORFNames=OSJNBa0090H02.2, OSJNBb0111K12.10, P0683B02.14;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA   Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA   Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA   Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT   "A fine physical map of the rice chromosome 5.";
RL   Mol. Genet. Genomics 274:337-345(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=17196101; DOI=10.1186/1471-2229-6-33;
RA   Opassiri R., Pomthong B., Onkoksoong T., Akiyama T., Esen A.,
RA   Ketudat Cairns J.R.;
RT   "Analysis of rice glycosyl hydrolase family 1 and expression of Os4bglu12
RT   beta-glucosidase.";
RL   BMC Plant Biol. 6:33-33(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC         with release of beta-D-glucose.; EC=3.2.1.21;
CC         Evidence={ECO:0000250|UniProtKB:Q75I94};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAS79738.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AAV31351.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AAV32242.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AK105546; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AC121366; AAS79738.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AC135927; AAV32242.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AC137618; AAV31351.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008211; BAF17241.1; -; Genomic_DNA.
DR   EMBL; AP014961; BAS93641.1; -; Genomic_DNA.
DR   EMBL; AK105546; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015639292.1; XM_015783806.1.
DR   AlphaFoldDB; Q0DIT2; -.
DR   SMR; Q0DIT2; -.
DR   STRING; 39947.Q0DIT2; -.
DR   CAZy; GH1; Glycoside Hydrolase Family 1.
DR   GlyCosmos; Q0DIT2; 4 sites, No reported glycans.
DR   PaxDb; 39947-Q0DIT2; -.
DR   EnsemblPlants; Os05t0365600-01; Os05t0365600-01; Os05g0365600.
DR   GeneID; 4338556; -.
DR   Gramene; Os05t0365600-01; Os05t0365600-01; Os05g0365600.
DR   KEGG; osa:4338556; -.
DR   eggNOG; KOG0626; Eukaryota.
DR   HOGENOM; CLU_001859_1_0_1; -.
DR   InParanoid; Q0DIT2; -.
DR   OMA; DFMYGWI; -.
DR   OrthoDB; 3373839at2759; -.
DR   Proteomes; UP000000763; Chromosome 5.
DR   Proteomes; UP000059680; Chromosome 5.
DR   GO; GO:0033907; F:beta-D-fucosidase activity; IEA:UniProt.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProt.
DR   GO; GO:0008422; F:beta-glucosidase activity; IBA:GO_Central.
DR   GO; GO:0102483; F:scopolin beta-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353:SF29; BETA-GLUCOSIDASE 11; 1.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 1.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
DR   Genevisible; Q0DIT2; OS.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Glycosidase; Hydrolase; Reference proteome;
KW   Signal.
FT   SIGNAL          1..41
FT                   /evidence="ECO:0000255"
FT   CHAIN           42..528
FT                   /note="Beta-glucosidase 19"
FT                   /id="PRO_0000390336"
FT   ACT_SITE        209
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250|UniProtKB:Q7XSK0"
FT   ACT_SITE        423
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250|UniProtKB:Q7XSK0"
FT   BINDING         63
FT                   /ligand="a beta-D-glucoside"
FT                   /ligand_id="ChEBI:CHEBI:22798"
FT                   /evidence="ECO:0000250|UniProtKB:Q7XSK0"
FT   BINDING         163
FT                   /ligand="a beta-D-glucoside"
FT                   /ligand_id="ChEBI:CHEBI:22798"
FT                   /evidence="ECO:0000250|UniProtKB:Q7XSK0"
FT   BINDING         353
FT                   /ligand="a beta-D-glucoside"
FT                   /ligand_id="ChEBI:CHEBI:22798"
FT                   /evidence="ECO:0000250|UniProtKB:Q7XSK0"
FT   BINDING         423
FT                   /ligand="a beta-D-glucoside"
FT                   /ligand_id="ChEBI:CHEBI:22798"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SPP9"
FT   BINDING         464
FT                   /ligand="a beta-D-glucoside"
FT                   /ligand_id="ChEBI:CHEBI:22798"
FT                   /evidence="ECO:0000250|UniProtKB:Q7XSK0"
FT   BINDING         480
FT                   /ligand="a beta-D-glucoside"
FT                   /ligand_id="ChEBI:CHEBI:22798"
FT                   /evidence="ECO:0000250|UniProtKB:Q1XH05"
FT   CARBOHYD        236
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        241
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        424
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        429
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   DISULFID        228..237
FT                   /evidence="ECO:0000250|UniProtKB:Q7XSK0"
SQ   SEQUENCE   528 AA;  59279 MW;  F27218C6CFE68F2C CRC64;
     MCGCASGEDA METRRPLHPL LLFFSPWLLL LLLLVVQGVR SLQFTRDDFP DGFTFGAGTA
     AFQYEGAAAE DGRTPSIWDT YAHSWRNPGG ETGDVACDGY HKYKEDVMLM NETGLEAYRF
     TISWSRLIPS GRGAVNPKGL QFYNSMINEL VKAGIQIHAV LYHIDLPQSL QDEYGGWVSP
     KVVDDFAAYA DVCFREFGDR VAHWTTSIEP NVMAQSGYDD GYLPPNRCSY PFGRSNCTLG
     NSTVEPYLFI HHTLLAHASA VRLYREKHQA AQKGVVGMNI YSMWFYPLTE STEDIAATER
     VKDFMYGWIL HPLVFGDYPE TMKKAAGSRL PLFSDYESEL VTNAFDFIGL NHYTSNYVSD
     NSNAVKAPLQ DVTDDISSLF WASKNSTPTR EFLPGTSLDP RGLELALEYL QEKYGNLLFY
     IQENGSGSNA TLDDVGRIDC LTQYIAATLR SIRNGANVKG YCVWSFMDQY EMFGDYKAHF
     GIVAVDFGSE ELTRQPRRSA RWYSDFLKNN AVIKVDDGSV STAFHAQL
//