Reviewed, UniProtKB/Swiss-Prot Q0DHL5 (LAC11_ORYSJ)

Names and origin

Protein names

Recommended name:
    Putative laccase-11
    EC=1.10.3.2
Alternative name(s):
    Benzenediol:oxygen oxidoreductase 11
    Urishiol oxidase 11
    Diphenol oxidase 11

Gene names

Name:	LAC11
Ordered Locus Names:	Os05g0458300, LOC_Os05g38390
ORF Names:	OsJ_018044

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	540 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Uncertain.

General annotation (Comments)

Function	Lignin degradation and detoxification of lignin-derived products By similarity.
Catalytic activity	4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O.
Cofactor	Binds 4 copper ions per monomer By similarity.
Subcellular location	Secreted › extracellular space › apoplastPotential.
Sequence similarities	Belongs to the multicopper oxidase family. Contains 3 plastocyanin-like domains.
Caution	Lacks the signal peptide, which is one of the conserved features of the laccases. Could be the product of a pseudogene.
Sequence caution	The sequence BAF17658.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Lignin degradation
Cellular component	Apoplast Secreted
Domain	Repeat
Ligand	Copper Metal-binding
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	lignin catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	apoplast Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	copper ion binding Inferred from electronic annotation. Source: InterPro laccase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 540	540	Putative laccase-11		PRO_0000291896
Regions
	Domain	1 – 114	114	Plastocyanin-like 1
	Domain	124 – 279	156	Plastocyanin-like 2
	Domain	389 – 523	135	Plastocyanin-like 3
Sites
	Metal binding	48	1	Copper 1 By similarity
	Metal binding	50	1	Copper 2 By similarity
	Metal binding	93	1	Copper 2 By similarity
	Metal binding	95	1	Copper 3 By similarity
	Metal binding	440	1	Copper 4 By similarity
	Metal binding	443	1	Copper 1 By similarity
	Metal binding	445	1	Copper 3 By similarity
	Metal binding	502	1	Copper 3 By similarity
	Metal binding	503	1	Copper 4 By similarity
	Metal binding	504	1	Copper 2 By similarity
	Metal binding	508	1	Copper 4 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0DHL5-1 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: C35A55C8FA490CF7	FASTA	540	58,622
	10 20 30 40 50 60 MATVTRLCVT KSVPTVNGQF PGPKLVVREG DTLVIRVTNN INNNVTFHWH GIRQVRSGWA 70 80 90 100 110 120 DGPAYITQCP IRSGGSYVYR FTVTGQRGTL WWHAHFSWLR ATLYGPLVIL PPRGVAYPFP 130 140 150 160 170 180 KPHREVPLLL GEWFNADPEA VIKQALQTGG GPNVSDAYTF NGLPGPTYNC SSSNDTFKLR 190 200 210 220 230 240 VRPGKTYLLR LINAALNDEL FFGVANHTLM VVQADASYVK PFAATALVIS PGQTMDVLLT 250 260 270 280 290 300 AAANNPPSRS FAIAVAPYTN TVGTFDNTTA VAVLEYYGAA TSAAALRSLP LPSLPAYNDT 310 320 330 340 350 360 GAVANFSASF RSLASAQYPA RVPRTVDRHF FFAVGLGADP CQSPVNGTCQ GPNNTRFAAS 370 380 390 400 410 420 MNNVSFVMPR TSLLQAHYQR RYNGVLAANF PAAPRTPFNY TGTPPNNTFV THGTRVVPLS 430 440 450 460 470 480 FNTTVEVVLQ DTSILGAESH PLHLHGYDFY VVGTGFGNYD ASNDTAKYNL VDPVQRNTIS 490 500 510 520 530 540 VPTAGWVAIR FVADNPGVWI MHCHLDVHLS WGLSMAWLVN DGPLPNQKLP PPPSDIPMCS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A fine physical map of the rice chromosome 5." Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J., Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F., Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y. Mol. Genet. Genomics 274:337-345(2005) [PubMed: 16261349] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP008211 Genomic DNA. Translation: BAF17658.1. Sequence problems. CM000142 Genomic DNA. Translation: EAZ34561.1.
RefSeq	NP_001055744.1.
UniGene	Os.80267
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4339001.
KEGG	osa:4339001.
Family and domain databases
InterPro	IPR001117. Cu-oxidase. IPR011707. Cu-oxidase_3. IPR002355. Cu_oxidase_Cu_BS. IPR008972. Cupredoxin. IPR017761. Laccase. [Graphical view]
Gene3D	G3DSA:2.60.40.420. Cupredoxin. 1 hit.
Pfam	PF00394. Cu-oxidase. 1 hit. PF07732. Cu-oxidase_3. 1 hit. [Graphical view]
PROSITE	PS00079. MULTICOPPER_OXIDASE1. 1 hit. PS00080. MULTICOPPER_OXIDASE2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LAC11_ORYSJ

Accession

Primary (citable) accession number: Q0DHL5
Secondary accession number(s): A3B4S2

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	June 26, 2007
Last modified:	November 25, 2008
This is version 20 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)