Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q0DHL2

- LAC12_ORYSJ

UniProt

Q0DHL2 - LAC12_ORYSJ

Protein

Laccase-12/13

Gene

LAC12

more
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (17 Oct 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Lignin degradation and detoxification of lignin-derived products.By similarity

    Catalytic activityi

    4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

    Cofactori

    Binds 4 copper ions per monomer.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi85 – 851Copper 1By similarity
    Metal bindingi87 – 871Copper 2By similarity
    Metal bindingi130 – 1301Copper 2By similarity
    Metal bindingi132 – 1321Copper 3By similarity
    Metal bindingi475 – 4751Copper 4By similarity
    Metal bindingi478 – 4781Copper 1By similarity
    Metal bindingi480 – 4801Copper 3By similarity
    Metal bindingi537 – 5371Copper 3By similarity
    Metal bindingi538 – 5381Copper 4By similarity
    Metal bindingi539 – 5391Copper 2By similarity
    Metal bindingi543 – 5431Copper 4By similarity

    GO - Molecular functioni

    1. copper ion binding Source: InterPro
    2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lignin catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Lignin degradation

    Keywords - Ligandi

    Copper, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Laccase-12/13 (EC:1.10.3.2)
    Alternative name(s):
    Benzenediol:oxygen oxidoreductase 12/13
    Diphenol oxidase 12/13
    Urishiol oxidase 12/13
    Gene namesi
    Name:LAC12
    Ordered Locus Names:Os05g0458500, LOC_Os05g38410
    ORF Names:OJ1362_D02.9, OsJ_018046
    AND
    Name:LAC13
    Ordered Locus Names:Os05g0458600, LOC_Os05g38420
    ORF Names:OJ1362_D02.10
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 5

    Organism-specific databases

    GrameneiQ0DHL2.

    Subcellular locationi

    GO - Cellular componenti

    1. apoplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Apoplast, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2727Sequence AnalysisAdd
    BLAST
    Chaini28 – 574547Laccase-12/13PRO_0000291897Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi81 – 811N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi173 – 1731N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi190 – 1901N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi206 – 2061N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi242 – 2421N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi302 – 3021N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi335 – 3351N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi342 – 3421N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi381 – 3811N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi388 – 3881N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi398 – 3981N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi434 – 4341N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi441 – 4411N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi447 – 4471N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ0DHL2.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini35 – 151117Plastocyanin-like 1Add
    BLAST
    Domaini161 – 314154Plastocyanin-like 2Add
    BLAST
    Domaini424 – 558135Plastocyanin-like 3Add
    BLAST

    Sequence similaritiesi

    Belongs to the multicopper oxidase family.Curated
    Contains 3 plastocyanin-like domains.Curated

    Keywords - Domaini

    Repeat, Signal

    Phylogenomic databases

    eggNOGiCOG2132.
    HOGENOMiHOG000241916.
    OMAiWRNDTEA.

    Family and domain databases

    Gene3Di2.60.40.420. 3 hits.
    InterProiIPR001117. Cu-oxidase.
    IPR011706. Cu-oxidase_2.
    IPR011707. Cu-oxidase_3.
    IPR002355. Cu_oxidase_Cu_BS.
    IPR008972. Cupredoxin.
    IPR017761. Laccase.
    [Graphical view]
    PfamiPF00394. Cu-oxidase. 1 hit.
    PF07731. Cu-oxidase_2. 1 hit.
    PF07732. Cu-oxidase_3. 1 hit.
    [Graphical view]
    SUPFAMiSSF49503. SSF49503. 3 hits.
    TIGRFAMsiTIGR03389. laccase. 1 hit.
    PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
    PS00080. MULTICOPPER_OXIDASE2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q0DHL2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAASSVLRC CLLVAALMTL SAMGAEAITR QYLFDVQTTS VTRLCSTKSI    50
    VTVNGQYPGP TLFAREGDHV EVTVVNHSPY NMSIHWHGIR QLLSGWADGP 100
    SYITQCPIQP GGSYVYRFTI TGQRGTLWWH AHISWLRATV HGPMVILPPA 150
    GVGYPFPAPH EEVPIMFGEW WNNDTEAVIS QALQTGGGPN ISDAYTLNGL 200
    PGPLYNCSAQ DTFKLKVKPG KTYMLRLINA ALNDELFFSI ANHTLTVVDV 250
    DALYVKPFTV DTLIIAPGQT SNVLLTAKPT YPGASYYMLA RPYTTTQGTF 300
    DNTTVAGVLE YDDPCPTTAA GKIVPIFSPT LPQINDTNAV SNFTAKLRSL 350
    ASAGYPAAVP QQVDHRFFFT VGLGTHPCAV NGTCQGPNGS RFAASINNVS 400
    FVLPATALLQ SHFAGKSKGV YASNFPYYPL NPFNYTGTPP NNTNVMNGTK 450
    VLVLPYGANV ELVMQDTSIL GAESHPLHLH GFNFFVVGQG FGNFDPINDP 500
    AKFNLYDPVE RNTVGVPAGG WVAIRFHADN PGVWFMHCHL EVHMSWGLKM 550
    AWLVLDGSRP DQKLPPPPLD LPKC 574
    Length:574
    Mass (Da):62,348
    Last modified:October 17, 2006 - v1
    Checksum:i27DD915DD4F41C13
    GO

    Sequence cautioni

    The sequence AK068047 differs from that shown. Reason: Frameshift at position 77.
    The sequence AAU44018.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence AAU44019.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence BAF17660.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence EAZ34563.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC105770 Genomic DNA. Translation: AAU44018.1. Sequence problems.
    AC105770 Genomic DNA. Translation: AAU44019.1. Sequence problems.
    AP008211 Genomic DNA. Translation: BAF17660.1. Sequence problems.
    AP008211 Genomic DNA. Translation: BAF17661.1.
    CM000142 Genomic DNA. Translation: EAZ34563.1. Sequence problems.
    AK068047 mRNA. No translation available.
    RefSeqiNP_001055746.1. NM_001062281.1.
    NP_001055747.1. NM_001062282.1.
    UniGeneiOs.51049.

    Genome annotation databases

    EnsemblPlantsiOS05T0458500-00; OS05T0458500-00; OS05G0458500.
    OS05T0458600-01; OS05T0458600-01; OS05G0458600.
    GeneIDi4339003.
    4339004.
    KEGGiosa:4339003.
    osa:4339004.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC105770 Genomic DNA. Translation: AAU44018.1 . Sequence problems.
    AC105770 Genomic DNA. Translation: AAU44019.1 . Sequence problems.
    AP008211 Genomic DNA. Translation: BAF17660.1 . Sequence problems.
    AP008211 Genomic DNA. Translation: BAF17661.1 .
    CM000142 Genomic DNA. Translation: EAZ34563.1 . Sequence problems.
    AK068047 mRNA. No translation available.
    RefSeqi NP_001055746.1. NM_001062281.1.
    NP_001055747.1. NM_001062282.1.
    UniGenei Os.51049.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q0DHL2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS05T0458500-00 ; OS05T0458500-00 ; OS05G0458500 .
    OS05T0458600-01 ; OS05T0458600-01 ; OS05G0458600 .
    GeneIDi 4339003.
    4339004.
    KEGGi osa:4339003.
    osa:4339004.

    Organism-specific databases

    Gramenei Q0DHL2.

    Phylogenomic databases

    eggNOGi COG2132.
    HOGENOMi HOG000241916.
    OMAi WRNDTEA.

    Family and domain databases

    Gene3Di 2.60.40.420. 3 hits.
    InterProi IPR001117. Cu-oxidase.
    IPR011706. Cu-oxidase_2.
    IPR011707. Cu-oxidase_3.
    IPR002355. Cu_oxidase_Cu_BS.
    IPR008972. Cupredoxin.
    IPR017761. Laccase.
    [Graphical view ]
    Pfami PF00394. Cu-oxidase. 1 hit.
    PF07731. Cu-oxidase_2. 1 hit.
    PF07732. Cu-oxidase_3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49503. SSF49503. 3 hits.
    TIGRFAMsi TIGR03389. laccase. 1 hit.
    PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
    PS00080. MULTICOPPER_OXIDASE2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (OS05G0458500 AND OS05G0458600).
      Strain: cv. Nipponbare.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (OS05G0458500 AND OS05G0458600).
      Strain: cv. Nipponbare.
    3. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    4. "The genomes of Oryza sativa: a history of duplications."
      Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
      , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
      PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (OS05G0458500 AND OS05G0458600).
      Strain: cv. Nipponbare.
    5. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (OS05G0458600).
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiLAC12_ORYSJ
    AccessioniPrimary (citable) accession number: Q0DHL2
    Secondary accession number(s): Q0DHL3, Q65XF7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 26, 2007
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3