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Q0DHL2

- LAC12_ORYSJ

UniProt

Q0DHL2 - LAC12_ORYSJ

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Protein

Laccase-12/13

Gene
LAC12, Os05g0458500, LOC_Os05g38410, OJ1362_D02.9, OsJ_018046
LAC13, Os05g0458600, LOC_Os05g38420, OJ1362_D02.10
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products By similarity.

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Binds 4 copper ions per monomer By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi85 – 851Copper 1 By similarity
Metal bindingi87 – 871Copper 2 By similarity
Metal bindingi130 – 1301Copper 2 By similarity
Metal bindingi132 – 1321Copper 3 By similarity
Metal bindingi475 – 4751Copper 4 By similarity
Metal bindingi478 – 4781Copper 1 By similarity
Metal bindingi480 – 4801Copper 3 By similarity
Metal bindingi537 – 5371Copper 3 By similarity
Metal bindingi538 – 5381Copper 4 By similarity
Metal bindingi539 – 5391Copper 2 By similarity
Metal bindingi543 – 5431Copper 4 By similarity

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Organism-specific databases

Protein namesi
Recommended name:
Laccase-12/13 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 12/13
Diphenol oxidase 12/13
Urishiol oxidase 12/13
Gene namesi
Name:LAC12
Ordered Locus Names:Os05g0458500, LOC_Os05g38410
ORF Names:OJ1362_D02.9, OsJ_018046
AND
Name:LAC13
Ordered Locus Names:Os05g0458600, LOC_Os05g38420
ORF Names:OJ1362_D02.10
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 5
GrameneiQ0DHL2.

Subcellular locationi

Secretedextracellular spaceapoplast Reviewed prediction

GO - Cellular componenti

  1. apoplast Source: UniProtKB-SubCell

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727 Reviewed predictionAdd
BLAST
Chaini28 – 574547Laccase-12/13PRO_0000291897Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi81 – 811N-linked (GlcNAc...) Reviewed prediction
Glycosylationi173 – 1731N-linked (GlcNAc...) Reviewed prediction
Glycosylationi190 – 1901N-linked (GlcNAc...) Reviewed prediction
Glycosylationi206 – 2061N-linked (GlcNAc...) Reviewed prediction
Glycosylationi242 – 2421N-linked (GlcNAc...) Reviewed prediction
Glycosylationi302 – 3021N-linked (GlcNAc...) Reviewed prediction
Glycosylationi335 – 3351N-linked (GlcNAc...) Reviewed prediction
Glycosylationi342 – 3421N-linked (GlcNAc...) Reviewed prediction
Glycosylationi381 – 3811N-linked (GlcNAc...) Reviewed prediction
Glycosylationi388 – 3881N-linked (GlcNAc...) Reviewed prediction
Glycosylationi398 – 3981N-linked (GlcNAc...) Reviewed prediction
Glycosylationi434 – 4341N-linked (GlcNAc...) Reviewed prediction
Glycosylationi441 – 4411N-linked (GlcNAc...) Reviewed prediction
Glycosylationi447 – 4471N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ0DHL2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini35 – 151117Plastocyanin-like 1Add
BLAST
Domaini161 – 314154Plastocyanin-like 2Add
BLAST
Domaini424 – 558135Plastocyanin-like 3Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
OMAiWRNDTEA.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0DHL2-1 [UniParc]FASTAAdd to Basket

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MAAASSVLRC CLLVAALMTL SAMGAEAITR QYLFDVQTTS VTRLCSTKSI    50
VTVNGQYPGP TLFAREGDHV EVTVVNHSPY NMSIHWHGIR QLLSGWADGP 100
SYITQCPIQP GGSYVYRFTI TGQRGTLWWH AHISWLRATV HGPMVILPPA 150
GVGYPFPAPH EEVPIMFGEW WNNDTEAVIS QALQTGGGPN ISDAYTLNGL 200
PGPLYNCSAQ DTFKLKVKPG KTYMLRLINA ALNDELFFSI ANHTLTVVDV 250
DALYVKPFTV DTLIIAPGQT SNVLLTAKPT YPGASYYMLA RPYTTTQGTF 300
DNTTVAGVLE YDDPCPTTAA GKIVPIFSPT LPQINDTNAV SNFTAKLRSL 350
ASAGYPAAVP QQVDHRFFFT VGLGTHPCAV NGTCQGPNGS RFAASINNVS 400
FVLPATALLQ SHFAGKSKGV YASNFPYYPL NPFNYTGTPP NNTNVMNGTK 450
VLVLPYGANV ELVMQDTSIL GAESHPLHLH GFNFFVVGQG FGNFDPINDP 500
AKFNLYDPVE RNTVGVPAGG WVAIRFHADN PGVWFMHCHL EVHMSWGLKM 550
AWLVLDGSRP DQKLPPPPLD LPKC 574
Length:574
Mass (Da):62,348
Last modified:October 17, 2006 - v1
Checksum:i27DD915DD4F41C13
GO

Sequence cautioni

The sequence AK068047 differs from that shown. Reason: Frameshift at position 77.
The sequence AAU44018.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence AAU44019.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence BAF17660.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence EAZ34563.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC105770 Genomic DNA. Translation: AAU44018.1. Sequence problems.
AC105770 Genomic DNA. Translation: AAU44019.1. Sequence problems.
AP008211 Genomic DNA. Translation: BAF17660.1. Sequence problems.
AP008211 Genomic DNA. Translation: BAF17661.1.
CM000142 Genomic DNA. Translation: EAZ34563.1. Sequence problems.
AK068047 mRNA. No translation available.
RefSeqiNP_001055746.1. NM_001062281.1.
NP_001055747.1. NM_001062282.1.
UniGeneiOs.51049.

Genome annotation databases

EnsemblPlantsiOS05T0458500-00; OS05T0458500-00; OS05G0458500.
OS05T0458600-01; OS05T0458600-01; OS05G0458600.
GeneIDi4339003.
4339004.
KEGGiosa:4339003.
osa:4339004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC105770 Genomic DNA. Translation: AAU44018.1 . Sequence problems.
AC105770 Genomic DNA. Translation: AAU44019.1 . Sequence problems.
AP008211 Genomic DNA. Translation: BAF17660.1 . Sequence problems.
AP008211 Genomic DNA. Translation: BAF17661.1 .
CM000142 Genomic DNA. Translation: EAZ34563.1 . Sequence problems.
AK068047 mRNA. No translation available.
RefSeqi NP_001055746.1. NM_001062281.1.
NP_001055747.1. NM_001062282.1.
UniGenei Os.51049.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q0DHL2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS05T0458500-00 ; OS05T0458500-00 ; OS05G0458500 .
OS05T0458600-01 ; OS05T0458600-01 ; OS05G0458600 .
GeneIDi 4339003.
4339004.
KEGGi osa:4339003.
osa:4339004.

Organism-specific databases

Gramenei Q0DHL2.

Phylogenomic databases

eggNOGi COG2132.
HOGENOMi HOG000241916.
OMAi WRNDTEA.

Family and domain databases

Gene3Di 2.60.40.420. 3 hits.
InterProi IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view ]
Pfami PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 3 hits.
TIGRFAMsi TIGR03389. laccase. 1 hit.
PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (OS05G0458500 AND OS05G0458600).
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (OS05G0458500 AND OS05G0458600).
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (OS05G0458500 AND OS05G0458600).
    Strain: cv. Nipponbare.
  5. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (OS05G0458600).
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLAC12_ORYSJ
AccessioniPrimary (citable) accession number: Q0DHL2
Secondary accession number(s): Q0DHL3, Q65XF7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: October 17, 2006
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi