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Protein

Mannan endo-1,4-beta-mannosidase 6

Gene

MAN6

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei224Proton donorBy similarity1
Active sitei344NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Protein family/group databases

CAZyiGH5 Glycoside Hydrolase Family 5

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan endo-1,4-beta-mannosidase 6 (EC:3.2.1.78)
Alternative name(s):
Beta-mannanase 6
Endo-beta-1,4-mannanase 6
OsMAN6
Gene namesi
Name:MAN6
Ordered Locus Names:Os06g0311600, LOC_Os06g20620
ORF Names:OSJNBb0005N06.19
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000027748723 – 440Mannan endo-1,4-beta-mannosidase 6Add BLAST418

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi173N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi176N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi230N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi330N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi356N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi401N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi418N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ0DCM5

Expressioni

Tissue specificityi

Expressed in stems and leaves, and at lower levels in roots and seeds.1 Publication

Gene expression databases

ExpressionAtlasiQ0DCM5 baseline and differential
GenevisibleiQ0DCM5 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os06g20620.1

Structurei

3D structure databases

ProteinModelPortaliQ0DCM5
SMRiQ0DCM5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IF1J Eukaryota
COG3934 LUCA
InParanoidiQ0DCM5
KOiK19355
OMAiMGLGVCR
OrthoDBiEOG09360BHK

Family and domain databases

InterProiView protein in InterPro
IPR001547 Glyco_hydro_5
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00150 Cellulase, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0DCM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQERRLYSL LGLLLLLAVV YLTWFPTTHD GGGGGGGGWV KLPVPWLQPR
60 70 80 90 100
MPFAARRGTH FVDADTGSPL YVNGWNSYWL LPARSPALAA EMLRRGRRMG
110 120 130 140 150
LSVCRTWAFS DGGPGALQIS PGRFSEAVFQ VLDYVIYEAR RNHIRLILCL
160 170 180 190 200
VNNLDNLGGK AQYVQWAQAA GANMTNSTDS FYSHPTIKRY YKDYVKAILT
210 220 230 240 250
RRNSYSRIRY SDEPAIFAWE LMNEPRCVSN SSGPYLQAWI AEMAAYVKSL
260 270 280 290 300
DTNHLVTVGT EGFYGPGIAE RLGVNPGEWA ASLCSDFIQN SAVEHIDFAS
310 320 330 340 350
VHAYPDSWLP RASLEEKVRY LSNWVDSHLN DSEQILKKPV LFTEVGYLQH
360 370 380 390 400
SDANSNSTVD RDIILRIVYD KIYDSARKLQ AGSGALIWQL MVEGTHMYGD
410 420 430 440
NFSVVARDRP STYSLITNQS CRLQRLYGEG DPGWQCSIPP
Length:440
Mass (Da):49,455
Last modified:February 6, 2007 - v2
Checksum:i244DD2B94365FAB3
GO

Sequence cautioni

The sequence BAF19398 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti354N → S in AK242683 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004583 Genomic DNA Translation: BAD61770.1
AP008212 Genomic DNA Translation: BAF19398.2 Sequence problems.
AP014962 Genomic DNA Translation: BAS97441.1
AK242683 mRNA No translation available.
RefSeqiXP_015640965.1, XM_015785479.1
UniGeneiOs.61630

Genome annotation databases

EnsemblPlantsiOs06t0311600-01; Os06t0311600-01; Os06g0311600
GeneIDi4340863
GrameneiOs06t0311600-01; Os06t0311600-01; Os06g0311600
KEGGiosa:4340863

Similar proteinsi

Entry informationi

Entry nameiMAN6_ORYSJ
AccessioniPrimary (citable) accession number: Q0DCM5
Secondary accession number(s): A0A0N7KM01, Q5Z7X8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: February 28, 2018
This is version 79 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome