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Q0DCM5 (MAN6_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannan endo-1,4-beta-mannosidase 6
EC=3.2.1.78
Alternative name(s):
Beta-mannanase 6
Endo-beta-1,4-mannanase 6
OsMAN6
Gene names
Name:MAN6
Ordered Locus Names:Os06g0311600, LOC_Os06g20620
ORF Names:OSJNBb0005N06.19
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

Subcellular location

Secreted Potential.

Tissue specificity

Expressed in stems and leaves, and at lower levels in roots and seeds. Ref.3

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Sequence caution

The sequence BAF19398.2 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmannan endo-1,4-beta-mannosidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 440418Mannan endo-1,4-beta-mannosidase 6
PRO_0000277487

Sites

Active site2241Proton donor By similarity
Active site3441Nucleophile By similarity

Amino acid modifications

Glycosylation1731N-linked (GlcNAc...) Potential
Glycosylation1761N-linked (GlcNAc...) Potential
Glycosylation2301N-linked (GlcNAc...) Potential
Glycosylation3301N-linked (GlcNAc...) Potential
Glycosylation3561N-linked (GlcNAc...) Potential
Glycosylation4011N-linked (GlcNAc...) Potential
Glycosylation4181N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict3541N → S in AK242683. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q0DCM5 [UniParc].

Last modified February 6, 2007. Version 2.
Checksum: 244DD2B94365FAB3

FASTA44049,455
        10         20         30         40         50         60 
MRQERRLYSL LGLLLLLAVV YLTWFPTTHD GGGGGGGGWV KLPVPWLQPR MPFAARRGTH 

        70         80         90        100        110        120 
FVDADTGSPL YVNGWNSYWL LPARSPALAA EMLRRGRRMG LSVCRTWAFS DGGPGALQIS 

       130        140        150        160        170        180 
PGRFSEAVFQ VLDYVIYEAR RNHIRLILCL VNNLDNLGGK AQYVQWAQAA GANMTNSTDS 

       190        200        210        220        230        240 
FYSHPTIKRY YKDYVKAILT RRNSYSRIRY SDEPAIFAWE LMNEPRCVSN SSGPYLQAWI 

       250        260        270        280        290        300 
AEMAAYVKSL DTNHLVTVGT EGFYGPGIAE RLGVNPGEWA ASLCSDFIQN SAVEHIDFAS 

       310        320        330        340        350        360 
VHAYPDSWLP RASLEEKVRY LSNWVDSHLN DSEQILKKPV LFTEVGYLQH SDANSNSTVD 

       370        380        390        400        410        420 
RDIILRIVYD KIYDSARKLQ AGSGALIWQL MVEGTHMYGD NFSVVARDRP STYSLITNQS 

       430        440 
CRLQRLYGEG DPGWQCSIPP

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"The endo-beta-mannanase gene families in Arabidopsis, rice, and poplar."
Yuan J.S., Yang X., Lai J., Lin H., Cheng Z.-M., Nonogaki H., Chen F.
Funct. Integr. Genomics 7:1-16(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, TISSUE SPECIFICITY.
[4]"Oryza sativa full length cDNA."
Kikuchi S.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP004583 Genomic DNA. Translation: BAD61770.1.
AP008212 Genomic DNA. Translation: BAF19398.2. Sequence problems.
AK242683 mRNA. No translation available.
RefSeqNP_001057484.2. NM_001064019.2.
UniGeneOs.61630.

3D structure databases

ProteinModelPortalQ0DCM5.
ModBaseSearch...

Protein family/group databases

CAZyGH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os06g20620.1; LOC_Os06g20620.1; LOC_Os06g20620.
GeneID4340863.
KEGGdosa:Os06t0311600-01.
osa:4340863.

Organism-specific databases

GrameneQ0DCM5.

Phylogenomic databases

eggNOGCOG3934.
OMASPGRFSE.
ProtClustDBCLSN2696147.

Gene expression databases

ArrayExpressQ0DCM5.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMSSF51445. Glyco_hydro_cat. 1 hit.
PROSITEPS00659. GLYCOSYL_HYDROL_F5. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMAN6_ORYSJ
AccessionPrimary (citable) accession number: Q0DCM5
Secondary accession number(s): Q5Z7X8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 1, 2013
This is version 53 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

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