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Protein

Probable cutinase 4

Gene

ATEG_02133

Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.By similarity

Catalytic activityi

Cutin + H2O = cutin monomers.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei131 – 1311By similarity
Active sitei186 – 1861By similarity
Active sitei199 – 1991By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Serine esterase

Protein family/group databases

ESTHERiasptn-cuti4. Cutinase.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cutinase 4 (EC:3.1.1.74)
Alternative name(s):
Cutin hydrolase 4
Gene namesi
ORF Names:ATEG_02133
OrganismiAspergillus terreus (strain NIH 2624 / FGSC A1156)
Taxonomic identifieri341663 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000007963 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ATEG_02133.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 219202Probable cutinase 4PRO_0000395258Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi41 ↔ 189By similarity
Glycosylationi99 – 991N-linked (GlcNAc...)Sequence analysis
Disulfide bondi120 ↔ 182By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ0CW01.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cutinase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000171425.
OMAiLENGICK.
OrthoDBiEOG779P8P.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000675. Cutinase/axe.
IPR011150. Cutinase_monf.
[Graphical view]
PfamiPF01083. Cutinase. 1 hit.
[Graphical view]
PRINTSiPR00129. CUTINASE.
SMARTiSM01110. Cutinase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00155. CUTINASE_1. 1 hit.
PS00931. CUTINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0CW01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILPSLLVAS LSALAAAGPV PPSALEARQS ESASDLENGI CKPVVLIFAR
60 70 80 90 100
GSTESGNMGY IAGMPTCNAL KTKLGSDQVA CQGVGGAYTA GLIPNFLPNN
110 120 130 140 150
TDQASIDEAT KMFDLAHTQC PDAQIVAGGY SQGTAVMDGS IQALPDDIKS
160 170 180 190 200
TVKGVVLFGF TRNLQDNGQI PNYPKDQTKV ICAPGDLVCD GTLIITPAHL
210
TYALYAGEAA EFLASKVSA
Length:219
Mass (Da):22,551
Last modified:October 17, 2006 - v1
Checksum:iEAE57BCC780332C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476596 Genomic DNA. Translation: EAU37095.1.
RefSeqiXP_001211311.1. XM_001211311.1.

Genome annotation databases

EnsemblFungiiCADATEAT00007697; CADATEAP00007697; CADATEAG00007697.
GeneIDi4317099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476596 Genomic DNA. Translation: EAU37095.1.
RefSeqiXP_001211311.1. XM_001211311.1.

3D structure databases

ProteinModelPortaliQ0CW01.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

ESTHERiasptn-cuti4. Cutinase.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADATEAT00007697; CADATEAP00007697; CADATEAG00007697.
GeneIDi4317099.

Organism-specific databases

EuPathDBiFungiDB:ATEG_02133.

Phylogenomic databases

HOGENOMiHOG000171425.
OMAiLENGICK.
OrthoDBiEOG779P8P.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000675. Cutinase/axe.
IPR011150. Cutinase_monf.
[Graphical view]
PfamiPF01083. Cutinase. 1 hit.
[Graphical view]
PRINTSiPR00129. CUTINASE.
SMARTiSM01110. Cutinase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00155. CUTINASE_1. 1 hit.
PS00931. CUTINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NIH 2624 / FGSC A1156.

Entry informationi

Entry nameiCUTI4_ASPTN
AccessioniPrimary (citable) accession number: Q0CW01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: October 17, 2006
Last modified: July 6, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.