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Q0CVT0 (EIF3C_ASPTN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit C

Short name=eIF3c
Alternative name(s):
Eukaryotic translation initiation factor 3 93 kDa subunit homolog
Short name=eIF3 p93
Translation initiation factor eIF3, p93 subunit homolog
Gene names
Name:nip1
ORF Names:ATEG_02204
OrganismAspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]
Taxonomic identifier341663 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length864 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03002

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03002.

Sequence similarities

Belongs to the eIF-3 subunit C family.

Contains 1 PCI domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 864864Eukaryotic translation initiation factor 3 subunit C HAMAP-Rule MF_03002
PRO_0000364277

Regions

Domain643 – 773131PCI

Sequences

Sequence LengthMass (Da)Tools
Q0CVT0 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: D59B6A138A64DAA2

FASTA86497,317
        10         20         30         40         50         60 
MSRFFARGGS DSESSSEDEQ ELYSDREEEE QFSDSEEESS EAESSEEESS DDEGAGASRF 

        70         80         90        100        110        120 
LKNVSESEES EDEERVTVVK SAKDKRLDEL EGIIKAIENA EKINDWAVIS SEFDKLNRQI 

       130        140        150        160        170        180 
VKVTQAGPTP KIYIQTVADL EDFVNETIAK QKSSNKKMNA SNAKGFNAVK QRIKKNNKEY 

       190        200        210        220        230        240 
ATLIEKYRAD KDGFMAGGDE EPKPVISAPR ISKVERVEAP VAVTATADDD GFATVGRGGK 

       250        260        270        280        290        300 
TLQYTPESIL KHLRVIVESR GKKNTDRFEQ IRTMEKLLEV AQNPYQRIRI YLTLISTRFD 

       310        320        330        340        350        360 
LTSSSSANYM SVDQWKLAQQ EFSTLLSVLE SNREYVVTEG AEEWEDDEKQ PQVAAGETLH 

       370        380        390        400        410        420 
VPGSIVSYVE RLDDELTRSL QQIDPHTAEY IERLSDEKEL YTNLVRTQVY AEALTTSEKS 

       430        440        450        460        470        480 
DPRQDSLNRV IMRRLEHIYF KPAQVVTILE EGTWKSLPSN LASDITPRAN SGEVTSLVQT 

       490        500        510        520        530        540 
LCNYLFRHSD GILRARAMLC QIYFLALHDQ YYRSRDLMLM SHLTENIANF DVSTQILFNR 

       550        560        570        580        590        600 
TLVQIGLCAF RAGLVYEAQN TLSEVCGSGR QKELLAQGII LQRYSTVSPE QERLERQRQL 

       610        620        630        640        650        660 
PFHMHINLEL LECIYLTSSM FLEVPLMAQT SSSPEMKRRV ISKTFRRMLD YNERQVFTGP 

       670        680        690        700        710        720 
AENTRDGVIM SAKFLAAGDW KKAAEMLNSI KIWDLMPQPE KIKEMLSQQI QEEGLRTYLF 

       730        740        750        760        770        780 
TYAPFYDSVS IATLSNMFEL PEKKIQAIIS RMISHEELAA ALDQVNNAIV FRKGVELSRL 

       790        800        810        820        830        840 
QSQIVTLADK SMNLLEANEK TLEQRTQGMA NAFQRDQGAG ARGGRGAGRG GQARGGPRFP 

       850        860 
GGQQGRRPGG QQFSGGALGG AIKA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH476596 Genomic DNA. Translation: EAU37166.1.
RefSeqXP_001211382.1. XM_001211382.1.

3D structure databases

ProteinModelPortalQ0CVT0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING33178.CADATEAP00000001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADATEAT00000001; CADATEAP00000001; CADATEAG00000001.
GeneID4316925.

Phylogenomic databases

eggNOGNOG305883.
HOGENOMHOG000029414.
OMAISAPRIS.
OrthoDBEOG75QRCP.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
HAMAPMF_03002. eIF3c.
InterProIPR027516. EIF3C.
IPR008905. EIF3C_N_dom.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF05470. eIF-3c_N. 1 hit.
PF01399. PCI. 1 hit.
[Graphical view]
SMARTSM00088. PINT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEIF3C_ASPTN
AccessionPrimary (citable) accession number: Q0CVT0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: October 17, 2006
Last modified: May 14, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries