Q0CTV2 (ABFA_ASPTN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable alpha-N-arabinofuranosidase A
Short name=ABF A
Short name=Arabinosidase A
EC=3.2.1.55

Gene names

Name:	abfA
ORF Names:	ATEG_02882

Organism

Aspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]

Taxonomic identifier

341663 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus › Aspergillus terreus

Protein attributes

Sequence length	628 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Alpha-N-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose. Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides By similarity.
Catalytic activity	Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
Pathway	Glycan metabolism; L-arabinan degradation.
Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the glycosyl hydrolase 51 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Polysaccharide degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	L-arabinose metabolic process Inferred from electronic annotation. Source: InterPro arabinan catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway arabinose metabolic process Inferred from sequence or structural similarity. Source: UniProtKB
Cellular_component	extracellular region Inferred from sequence or structural similarity. Source: UniProtKB
Molecular_function	alpha-N-arabinofuranosidase activity Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25
	Chain	26 – 628	603	Probable alpha-N-arabinofuranosidase A		PRO_0000394600
Amino acid modifications
	Glycosylation	36	1	N-linked (GlcNAc...) Potential
	Glycosylation	51	1	N-linked (GlcNAc...) Potential
	Glycosylation	74	1	N-linked (GlcNAc...) Potential
	Glycosylation	152	1	N-linked (GlcNAc...) Potential
	Glycosylation	164	1	N-linked (GlcNAc...) Potential
	Glycosylation	260	1	N-linked (GlcNAc...) Potential
	Glycosylation	359	1	N-linked (GlcNAc...) Potential
	Glycosylation	404	1	N-linked (GlcNAc...) Potential
	Glycosylation	493	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q0CTV2 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 574064EADFD9BB18	FASTA	628	68,046
	10 20 30 40 50 60 MVAFSTISGL GALSLLFSII ESVDGVSLKV STDGGNSSSP LLYGFMFEDI NHSGDGGIYG 70 80 90 100 110 120 QMIQNNGLQG SSPNLTAWAS VGDGTISVDT TNPLTAAIPN SLKLDIKPDA TGAVGFTNEG 130 140 150 160 170 180 YWGIPVDGTE FQNSFWMKGD FSGEITVRLV GNETGTEYGS TTFNQSSSSD DYTKVSVKFP 190 200 210 220 230 240 TTKAPDGNVL YELTVDGESA QGSSLSFTLF ELFAQTYKSR SNGLKPQLAD ALESVKGSFL 250 260 270 280 290 300 RFPGGNNLEG NDVETRWKWN ETIGPLENRP GHQGTWGYFN TDGLGLDEYL YWCEDMNLTP 310 320 330 340 350 360 VLGVWAGFAL ESGGNTPITG DALTPYIEDV LNELEYVLGD PSTTYGKLRA SYGREEPWNV 370 380 390 400 410 420 TLVEIGNEDN LGGGCESYAE RFTAFYNAIH DAYPDLTLIA STDNASCLPS PLPEGAWVDY 430 440 450 460 470 480 HNYNTPDELV KQFGMFDNVD RSVPYFIGEY SRWEIPWPNM QGSVAEAVFM IGLERNSDVV 490 500 510 520 530 540 KMAAYAPLLQ LVNSTQWTPD LISFTQNPNM VIDSTSYYVQ QMFSVNRGDT IKEVTSDSAF 550 560 570 580 590 600 GPVYWVASSS GSSYYVKLAN YGADTQEVSV SIPGMSSGKL TVLADSDPEA YNSDTQTLVT 610 620 PSESNVQASN GQFSFTLPAW SVAVLTAN

References

[1]

"Annotation of the Aspergillus terreus NIH2624 genome." Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M., Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K. , Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J., Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W., Nierman W.C., Milne T., Madden K. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NIH 2624 / FGSC A1156.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH476597 Genomic DNA. Translation: EAU36156.1.
RefSeq	XP_001212060.1. XM_001212060.1.
3D structure databases
ProteinModelPortal	Q0CTV2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADATEAT00009779; CADATEAP00009779; CADATEAG00009779.
GeneID	4317643.
Phylogenomic databases
eggNOG	COG3534.
HOGENOM	HOG000115340.
OrthoDB	EOG4Z0FDW.
Enzyme and pathway databases
UniPathway	UPA00667.
Family and domain databases
InterPro	IPR010720. Alpha-L-AF_C. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Pfam	PF06964. Alpha-L-AF_C. 1 hit. [Graphical view]
SMART	SM00813. Alpha-L-AF_C. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ABFA_ASPTN

Accession

Primary (citable) accession number: Q0CTV2

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 15, 2010
Last sequence update:	October 17, 2006
Last modified:	March 6, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program