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Protein

Protein hir1

Gene

hir1

Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator, Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein hir1
Gene namesi
Name:hir1
ORF Names:ATEG_04180
OrganismiAspergillus terreus (strain NIH 2624 / FGSC A1156)
Taxonomic identifieri341663 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000007963 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ATEG_04180.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 999999Protein hir1PRO_0000286404Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ0CQ54.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati15 – 5440WD 1Add
BLAST
Repeati69 – 10840WD 2Add
BLAST
Repeati130 – 16940WD 3Add
BLAST
Repeati172 – 21140WD 4Add
BLAST
Repeati233 – 27644WD 5Add
BLAST
Repeati279 – 33961WD 6Add
BLAST
Repeati343 – 38442WD 7Add
BLAST

Sequence similaritiesi

Belongs to the WD repeat HIR1 family.Curated
Contains 7 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000208205.
OMAiFTWQRIS.
OrthoDBiEOG7NCVC9.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR031120. HIR1.
IPR011494. Hira.
IPR019015. HIRA_B_motif.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PANTHERiPTHR13831. PTHR13831. 1 hit.
PfamiPF07569. Hira. 1 hit.
PF09453. HIRA_B. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0CQ54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHIIKPVWLT HGGKLVVHDS SSSWHGPLTP TLLSTGERKD FEVYSCDVSP
60 70 80 90 100
DGSRLVTAAG DGYVRIWSTE AIRNTDDSSQ KPKQLASMSN HSGTIHTVRF
110 120 130 140 150
SPNGKYLASG ADDKIVCIYT LDANPPSHST FGWSYDSSIL VSVGLDSKVV
160 170 180 190 200
VWSGHTFEKL KTLSVHQSHV KGITFDPANK YFATASDDRT VKIFRFTSPA
210 220 230 240 250
PNSTAHDQMN NFVLETTISA PFQNSPLTAY FRRCSWSPDG MHIAAANAVN
260 270 280 290 300
GPVSSVAIIN RGSWDGDINL IGHEAPVEVC AFSPRLYSTQ PPNKQTPDNQ
310 320 330 340 350
GQAVTVIACA GGDKSLSIWI TTNPRPIVVA QELAAKSISD LAWSPDGTCL
360 370 380 390 400
YATALDGTIL AVRFEDGDLG YPMAMEENEK SLTKFGTNRR GAGITETTDG
410 420 430 440 450
LLLEEKSKAG ELKGVEGRMG ALMGDGHASA EATVNGKALS SNGAAPAQGT
460 470 480 490 500
SPTADAQKTQ TNGTTTPAAQ EADKPDPYQA KLERLKQRPT YTKDGKKRIA
510 520 530 540 550
PLLVSGAGAA ESSLPQARLM ASVSSQVKAD TPQSIVDLSK PFDGLPKGGL
560 570 580 590 600
AALLFGNKRK LAQLEGDEDG HVEKRVALAS QNGATPIMAN TPDGLLPAQP
610 620 630 640 650
QPPATGQQQT PEYIRPAVTN PCMAISQLRL AVPKVRSQIV RAIDSTGKPT
660 670 680 690 700
EPPGASSEAN KSRVDLVFEA RNPSPASLTG RAVDREPVRL TLFRGEQPLW
710 720 730 740 750
QDFLPRTVLL VTGNQSMWAA ACEDGSVYIW TPAGRRLVSA LVLEAQPVIL
760 770 780 790 800
ECNGPWILCI SAVGMCYVWN VKHLSSPHPP ISLQPVLDAA VHTLGAHPSS
810 820 830 840 850
APAITNARIN SEGRVIVALS NGEGYAYSPS MYTWQRMSEA WWAVGSQYWN
860 870 880 890 900
TTEAPVGNLQ STDSQDKDAK AAVSAGIIPF LERNTTNETL LRGRAYFLQR
910 920 930 940 950
LIKVLLSREG YESFESSVSI AHLENRLAAA LSLGAKEEFR LYLSMYAKRI
960 970 980 990
GAEGLKNKVE ELLKGLIGGK HRDLQRVTVP YAKLLGVVDE SEAGDAMET
Length:999
Mass (Da):107,339
Last modified:October 17, 2006 - v1
Checksum:iAA6AC51A5225F32F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476598 Genomic DNA. Translation: EAU35982.1.
RefSeqiXP_001213358.1. XM_001213358.1.

Genome annotation databases

EnsemblFungiiCADATEAT00009500; CADATEAP00009500; CADATEAG00009500.
GeneIDi4318578.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476598 Genomic DNA. Translation: EAU35982.1.
RefSeqiXP_001213358.1. XM_001213358.1.

3D structure databases

ProteinModelPortaliQ0CQ54.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADATEAT00009500; CADATEAP00009500; CADATEAG00009500.
GeneIDi4318578.

Organism-specific databases

EuPathDBiFungiDB:ATEG_04180.

Phylogenomic databases

HOGENOMiHOG000208205.
OMAiFTWQRIS.
OrthoDBiEOG7NCVC9.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR031120. HIR1.
IPR011494. Hira.
IPR019015. HIRA_B_motif.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PANTHERiPTHR13831. PTHR13831. 1 hit.
PfamiPF07569. Hira. 1 hit.
PF09453. HIRA_B. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NIH 2624 / FGSC A1156.

Entry informationi

Entry nameiHIR1_ASPTN
AccessioniPrimary (citable) accession number: Q0CQ54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: October 17, 2006
Last modified: June 8, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.