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Q0CLV1 (PHYA_ASPTN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-phytase A

EC=3.1.3.8
Alternative name(s):
3 phytase A
Myo-inositol hexakisphosphate phosphohydrolase A
Myo-inositol-hexaphosphate 3-phosphohydrolase A
Gene names
Name:phyA
ORF Names:ATEG_05333
OrganismAspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]
Taxonomic identifier341663 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length466 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of inorganic orthophosphate from phytate By similarity.

Catalytic activity

Myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.

Subunit structure

Monomer By similarity.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function3-phytase activity

Inferred from electronic annotation. Source: UniProtKB-EC

acid phosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 By similarity
Chain20 – 4664473-phytase A
PRO_0000283713

Sites

Active site821Nucleophile By similarity
Active site3621Proton donor By similarity

Amino acid modifications

Glycosylation271N-linked (GlcNAc...) Potential
Glycosylation1051N-linked (GlcNAc...) Potential
Glycosylation1201N-linked (GlcNAc...) Potential
Glycosylation2071N-linked (GlcNAc...) Potential
Glycosylation2301N-linked (GlcNAc...) Potential
Glycosylation3391N-linked (GlcNAc...) Potential
Glycosylation3521N-linked (GlcNAc...) Potential
Glycosylation3761N-linked (GlcNAc...) Potential
Disulfide bond31 ↔ 40 By similarity
Disulfide bond71 ↔ 414 By similarity
Disulfide bond215 ↔ 465 By similarity
Disulfide bond264 ↔ 282 By similarity
Disulfide bond436 ↔ 444 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0CLV1 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 95C75138C6F10045

FASTA46651,088
        10         20         30         40         50         60 
MGVFVVLLSI ATLFGSTSGT ALGPRGNHSD CNSVDHGYQC FPELSHKWGL YAPYFSLQDE 

        70         80         90        100        110        120 
SPFPLDVPDD CQITFVQALA RHGARSPTDS KTKAYAATIA AIQKNATTFP GKYAFLKSYN 

       130        140        150        160        170        180 
YSMGSEDLTP FGRNQLQDMG AQFYRRYDTL TRHINPFIRA ADSSRVHESA EKFVEGFQNA 

       190        200        210        220        230        240 
RQGDPRANPH QPSPRVDVVI PEGTAYNNTL EHSICTAFED STVGDAAADN FTAVFAPAIA 

       250        260        270        280        290        300 
KRLEADLPGV QLSADDVINL MAMCPFETVS LTDDAHTLSP FCDLFTAAEW TQYNYLLSLD 

       310        320        330        340        350        360 
KYYGYGGGNP LGPVQGVGWA NELIARLTHS PVHDHTCVNN TLDANPATFP LNATLYADFS 

       370        380        390        400        410        420 
HDSNLVSIFW ALGLYNGTKA LSQTTVEDTT QTDGYAAAWT VPFAARAYIE MMQCRAEKQP 

       430        440        450        460 
LVRVLVNDRV MPLHGCAVDN LGRCKRDDFV EGLSFARAGG NWAECF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH476600 Genomic DNA. Translation: EAU34402.1.
RefSeqXP_001214511.1. XM_001214511.1.

3D structure databases

ProteinModelPortalQ0CLV1.
SMRQ0CLV1. Positions 31-466.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADATEAT00004553; CADATEAP00004553; CADATEAG00004553.
GeneID4320687.

Phylogenomic databases

OMAWAQYSPY.
OrthoDBEOG7QC85C.

Family and domain databases

Gene3D3.40.50.1240. 1 hit.
InterProIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
IPR016274. Histidine_acid_Pase_euk.
[Graphical view]
PfamPF00328. His_Phos_2. 1 hit.
[Graphical view]
PIRSFPIRSF000894. Acid_phosphatase. 1 hit.
SUPFAMSSF53254. SSF53254. 1 hit.
PROSITEPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePHYA_ASPTN
AccessionPrimary (citable) accession number: Q0CLV1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: October 17, 2006
Last modified: June 11, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families