Q0CLE0 (STS1_ASPTN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Tethering factor for nuclear proteasome sts1

Gene names

Name:	sts1
ORF Names:	ATEG_05494

Organism

Aspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]

Taxonomic identifier

341663 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus › Aspergillus terreus

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins By similarity.
Subunit structure	Binds the proteasome By similarity.
Subcellular location	Cytoplasm By similarity. Nucleus By similarity.
Sequence similarities	Belongs to the cut8/STS1 family.

Ontologies

Keywords
Biological process	Protein transport Transport
Cellular component	Cytoplasm Nucleus
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 314	314	Tethering factor for nuclear proteasome sts1		PRO_0000409400

Sequences

	Sequence		Length	Mass (Da)
	Q0CLE0 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: B9A4973F602BC7DD	FASTA	314	34,394
	10 20 30 40 50 60 MNSLVATPPV PPHFYEYSRL ASARQMSTPT VTPNSRKRKA EDDTADHDGR MSASPTSSPA 70 80 90 100 110 120 FTPRTLPSAR NVKRTRPNIS GRPLSLPRLL ETLDTDALRG MLRSMCERHP SLADEIVHTA 130 140 150 160 170 180 PRPSVSSALQ VLRQYQSNLQ SSFPLGGNPA SDYAYNRVRQ PLGQLLDALS DFTPHFLPPN 190 200 210 220 230 240 ETQPSVSLSY LDDATEIIHA LPRWSTPQNN IERDSAYDEI CKAWILVIRE AAKRGGGFQL 250 260 270 280 290 300 QYGGWEQKLA KHNQNSGGKL QAAVHELASC LGWMHGPDTQ AYGGSGGNND LGSIREQLLS 310 GTYGLGTPVK VGPW

References

[1]

"Annotation of the Aspergillus terreus NIH2624 genome." Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M., Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K. , Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J., Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W., Nierman W.C., Milne T., Madden K. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NIH 2624 / FGSC A1156.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH476600 Genomic DNA. Translation: EAU34563.1.
RefSeq	XP_001214672.1. XM_001214672.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	33178.CADATEAP00004139.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADATEAT00004139; CADATEAP00004139; CADATEAG00004139.
GeneID	4320973.
Phylogenomic databases
eggNOG	NOG80406.
HOGENOM	HOG000188478.
OrthoDB	EOG4RJK9W.
Family and domain databases
InterPro	IPR013868. Nuclear_env_Cut8. [Graphical view]
Pfam	PF08559. Cut8. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

STS1_ASPTN

Accession

Primary (citable) accession number: Q0CLE0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 31, 2011
Last sequence update:	October 17, 2006
Last modified:	April 3, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program