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Q0CIL2 (XKS1_ASPTN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable D-xylulose kinase A

Short name=Xylulokinase A
EC=2.7.1.17
Gene names
Name:xkiA
ORF Names:ATEG_06472
OrganismAspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]
Taxonomic identifier341663 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length573 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway By similarity.

Catalytic activity

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Subcellular location

Cytoplasm By similarity.

Induction

By D-xylose, L-arabinose or L-arabitol.

Sequence similarities

Belongs to the FGGY kinase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Xylose metabolism
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylulokinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 573573Probable D-xylulose kinase A
PRO_0000393523

Regions

Nucleotide binding473 – 4742ATP By similarity

Sites

Binding site1001Substrate By similarity
Binding site1711Substrate By similarity
Binding site2871Substrate By similarity
Binding site2881Substrate By similarity
Binding site3681ATP By similarity
Binding site4771ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0CIL2 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: DE092A70270D0BAA

FASTA57363,415
        10         20         30         40         50         60 
MAISAAQNPL YIGFDLSTQQ LKGLVVNSDL KVVYLSKFDF DADSRGFPIK KGVITNEAEH 

        70         80         90        100        110        120 
EVYAPVAMWL QALDTVLDGL RQQGLDFSRV KGISGAGQQH GSVYWGDRAE DLLQNLDPSK 

       130        140        150        160        170        180 
SLEAQLSDAF SHPYSPNWQD ASTQKECDEF DAYLGSQEAL AQATGSKAHH RFTGPQILRF 

       190        200        210        220        230        240 
QRKYPDVYRH TQRISLVSSF LASLFLGRFA PFDISDVCGM NLWNIKQGAY DEKLLKLCAG 

       250        260        270        280        290        300 
SFGVDDLKRK LGPVYEDGGL NLGSIHRYYV DRYGFNPDCT IIPATGDNPA TILALPLRPS 

       310        320        330        340        350        360 
DAMVSLGTST TFLMSTPSYQ PHPATHFFNH PTTAGLYMFM LCYKNGGLAR EQIRDAVNDK 

       370        380        390        400        410        420 
LGSSDDVWAN FDRTALQTPP LGQKADSDPM KMGLFFPRPE IVPNLRSGQW RFDYNPADGS 

       430        440        450        460        470        480 
LHETTAGWDQ PLDEARAIIE SQMLSLRLRS RGLTSSPGDG KPPQPRRVYL VGGGSKNKAI 

       490        500        510        520        530        540 
AKIAGEILGG SEGVYKLEIG DNACALGAAY KAVWALERSN GQTFEDLIGQ RWKEEDFIEK 

       550        560        570 
IADGYQPGVF EKYGQAVEGF EKMELQVLQQ EKK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH476602 Genomic DNA. Translation: EAU33016.1.
RefSeqXP_001215650.1. XM_001215650.1.

3D structure databases

ProteinModelPortalQ0CIL2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING33178.CADATEAP00007642.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADATEAT00007642; CADATEAP00007642; CADATEAG00007642.
GeneID4322249.

Phylogenomic databases

eggNOGCOG1070.
HOGENOMHOG000174850.
OMAMICYCNG.
OrthoDBEOG7CRTZN.

Family and domain databases

InterProIPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view]
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXKS1_ASPTN
AccessionPrimary (citable) accession number: Q0CIL2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: October 17, 2006
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families