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Q0CI96

- BTGC_ASPTN

UniProt

Q0CI96 - BTGC_ASPTN

Protein

Probable glucan endo-1,3-beta-glucosidase btgC

Gene

btgC

Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 2 (15 Jun 2010)
      Previous versions | rss
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    Functioni

    Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan By similarity.By similarity

    Catalytic activityi

    Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei557 – 5571NucleophileBy similarity
    Active sitei625 – 6251Proton donorBy similarity

    GO - Molecular functioni

    1. glucan endo-1,3-beta-D-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. polysaccharide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glucan endo-1,3-beta-glucosidase btgC (EC:3.2.1.39)
    Alternative name(s):
    Endo-1,3-beta-glucanase btgC
    Laminarinase btgC
    Gene namesi
    Name:btgC
    ORF Names:ATEG_06588
    OrganismiAspergillus terreus (strain NIH 2624 / FGSC A1156)
    Taxonomic identifieri341663 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000007963: Unassembled WGS sequence

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 655655Probable glucan endo-1,3-beta-glucosidase btgCPRO_0000395127Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi426 – 4261N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi576 – 5761N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi602 – 6021N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 282282CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini304 – 655352ExtracellularSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei283 – 30321Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi143 – 15513Poly-AlaAdd
    BLAST
    Compositional biasi228 – 30881Gly-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 17 family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG5309.
    HOGENOMiHOG000173877.
    OrthoDBiEOG7P8PHC.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0CI96-1 [UniParc]FASTAAdd to Basket

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    MSGDPRSFSF NQGDDHPIDS SQQPLHPTNT MADSYSDRNW GAPGGLDHTH    50
    SMRTQSTATP GMDNLGPAAV GGGISGIALG VANSHDRQSG VDAFRDTDGG 100
    NFPAERGYNA PGSDNPYVPP PPAAAYDSSD NLTARSGAYG SSAALAAAAS 150
    APAGASNTSR RSFVDSPYQG VGALDAGPYQ RQSVYNNGDY PLVINPDEII 200
    DDGDDGFALP NSKSAGHKSR AVPAAAAGAA GGAAAGGLLG GIFKSKAAAE 250
    GPSYGPVPGA GIEAAEKGQW AKPKPGTGSR KRGWIVGIIL AVVIVGAIVG 300
    GAVGGTLGNR EKESPSSSET ASGDEKVNGD LGKDSDEIKS LMNNPNLHKV 350
    FPGMDYTPWG TQYPLCQKYP PSQNNVTRDI AVLSQLTNTV RLYGTDCNQT 400
    EMVLHAIDRL ELTEMKLWLG VWIDTNKTTC ERQLNQLYDV LDKTKDHSIF 450
    KGAIIGNEAL YRAGSSIAEA EKTLISYMTE VRDHFKKNNI NIPIATSDLG 500
    DNWNAELVKA SDVVMANVHP FFAGVSVDLA ASWTWDFWNN HNLVLTKGTD 550
    KKQIISEVGW PSGGGNDCGD GGNCPNDSAG SVAGIDEMNQ FMSDWVCQAL 600
    DNGTDYFWFE AFDEPWKIVY NTKNENWEDK WGLMDPARNL KDGLKIPDCG 650
    GKTAT 655
    Length:655
    Mass (Da):69,420
    Last modified:June 15, 2010 - v2
    Checksum:iC2560B77C3B3CAC5
    GO

    Sequence cautioni

    The sequence EAU33132.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence EAU33132.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476602 Genomic DNA. Translation: EAU33132.1. Sequence problems.
    RefSeqiXP_001215766.1. XM_001215766.1.

    Genome annotation databases

    GeneIDi4322381.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476602 Genomic DNA. Translation: EAU33132.1 . Sequence problems.
    RefSeqi XP_001215766.1. XM_001215766.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4322381.

    Phylogenomic databases

    eggNOGi COG5309.
    HOGENOMi HOG000173877.
    OrthoDBi EOG7P8PHC.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NIH 2624 / FGSC A1156.

    Entry informationi

    Entry nameiBTGC_ASPTN
    AccessioniPrimary (citable) accession number: Q0CI96
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: June 15, 2010
    Last modified: October 1, 2014
    This is version 34 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3