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Q0CHZ8

- EXGD_ASPTN

UniProt

Q0CHZ8 - EXGD_ASPTN

Protein

Probable glucan 1,3-beta-glucosidase D

Gene

exgD

Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (17 Oct 2006)
      Previous versions | rss
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    Functioni

    Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan By similarity.By similarity

    Catalytic activityi

    Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei604 – 6041Proton donorBy similarity
    Active sitei709 – 7091NucleophileBy similarity

    GO - Molecular functioni

    1. glucan exo-1,3-beta-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. polysaccharide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glucan 1,3-beta-glucosidase D (EC:3.2.1.58)
    Alternative name(s):
    Exo-1,3-beta-glucanase D
    Gene namesi
    Name:exgD
    ORF Names:ATEG_06686
    OrganismiAspergillus terreus (strain NIH 2624 / FGSC A1156)
    Taxonomic identifieri341663 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000007963: Unassembled WGS sequence

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 838838Probable glucan 1,3-beta-glucosidase DPRO_0000395167Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi383 – 3831N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi388 – 3881N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi400 – 4001N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi553 – 5531N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi565 – 5651N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi643 – 6431N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi696 – 6961N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi33178.CADATEAP00007048.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0CHZ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 310310CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini332 – 838507ExtracellularSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei311 – 33121Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi6 – 174169Arg-richAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG2730.
    HOGENOMiHOG000114462.
    OMAiNIITHYG.
    OrthoDBiEOG7ZPNTV.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001547. Glyco_hydro_5.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF00150. Cellulase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0CHZ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSHSRSRDR YRGRDESEPE RDRRHYSRRR YRETDYEDDE LDDDDYDRRR    50
    RYRRDDVYRR SRGQSRGYES HEYHEDDANE YDLAGEDPAV PLRRSRGDER 100
    ERSAGAYDDY DSPRRRDRHR DGDRRRRHRA YEAEGSPPRG APDHRRHRSR 150
    DDRRERAYES EREARRHRRR ERGREAAAAK HQSSDSTNSG SHLLSADALA 200
    KLRSEYDKED RSRAKADAKA EKKQRRKRPV VADQPRRLDP FPEETPRGQS 250
    KGRIVSGAYL EEGRSPEMKV RHRGGGGGGG AGSKWRDEGA SDSDMDGAEG 300
    GTPFWKKKKT WIAVGVVVVL LAIIIPVAVV VSKKNNEKKS DSTTDDTTPR 350
    NSNLDGISRD SIPDYAKGTV LDPWTWYDTM GFNVTFTNET VGGLSIMGLN 400
    STWDDSTRPN DNVPPLNEPF PYGSQPIRGV NLGGWLSIEP FIVPSLFESY 450
    SSVDGVVDEW TLCQKLGDSA ASRIERHYAT FITEQDFADI RDAGLDHVRI 500
    QFSYWAVTTY DGDQYVPKIS WRYLLRAIEY CRKYGLRVKL DPHGIPGSQN 550
    GWNHSGRQGP IGWLNGTDGQ LNRKRSLEMH DQLSQFFAQD RYKNIVTIYG 600
    LVNEPMMLSL PVEDVLDWST EATKLIQKNG ITAYVTVHDG FLNLSKWKQM 650
    LKTRPDRMFL DTHQYTIFNT AQIVMKHTEK IKLVCNDWHS MIQQINTTSA 700
    GWGPTICGEW SQADTDCTKY LNNVGRGTRW EGTFSLTDST AYCPTAKSGP 750
    SCSCSSANAD PSQYSDQYKK FLKTYAEAQM SAFETAQGWF YWTWHTESAP 800
    QWSYKTAWKN GFMPQKAYAP DFKCGDDVPD FGDLPENY 838
    Length:838
    Mass (Da):96,217
    Last modified:October 17, 2006 - v1
    Checksum:iB2070EDC943C81AB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476602 Genomic DNA. Translation: EAU33230.1.
    RefSeqiXP_001215864.1. XM_001215864.1.

    Genome annotation databases

    EnsemblFungiiCADATEAT00007048; CADATEAP00007048; CADATEAG00007048.
    GeneIDi4322028.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH476602 Genomic DNA. Translation: EAU33230.1 .
    RefSeqi XP_001215864.1. XM_001215864.1.

    3D structure databases

    ProteinModelPortali Q0CHZ8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 33178.CADATEAP00007048.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADATEAT00007048 ; CADATEAP00007048 ; CADATEAG00007048 .
    GeneIDi 4322028.

    Phylogenomic databases

    eggNOGi COG2730.
    HOGENOMi HOG000114462.
    OMAi NIITHYG.
    OrthoDBi EOG7ZPNTV.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001547. Glyco_hydro_5.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF00150. Cellulase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NIH 2624 / FGSC A1156.

    Entry informationi

    Entry nameiEXGD_ASPTN
    AccessioniPrimary (citable) accession number: Q0CHZ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3