ID   RIFK_ASPTN              Reviewed;         205 AA.
AC   Q0CHR1;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 15.
DE   RecName: Full=Riboflavin kinase;
DE            EC=2.7.1.26;
DE   AltName: Full=Flavin mononucleotide kinase 1;
GN   Name=fmn1; ORFNames=ATEG_06773;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae;
OC   mitosporic Trichocomaceae; Aspergillus.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M.,
RA   Engels R., Montgomery P., Pearson M., Howarth C., Larson L., Luoma S.,
RA   White J., Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C.,
RA   Denning D.W., Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the phosphorylation of riboflavin (vitamin B2)
CC       to form flavin mononucleotide (FMN) coenzyme (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + riboflavin = ADP + FMN.
CC   -!- COFACTOR: Zinc or magnesium (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; FMN biosynthesis; FMN from
CC       riboflavin (ATP route): step 1/1.
CC   -!- SIMILARITY: Belongs to the flavokinase family.
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DR   EMBL; CH476602; EAU33317.1; -; Genomic_DNA.
DR   RefSeq; XP_001215951.1; -.
DR   GeneID; 4321940; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008531; F:riboflavin kinase activity; IEA:EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009231; P:riboflavin biosynthetic process; IEA:InterPro.
DR   InterPro; IPR015865; Riboflavin_kinase.
DR   Gene3D; G3DSA:2.40.30.30; Riboflavin_kinase; 1.
DR   PANTHER; PTHR22749; Riboflavin_kinase; 1.
DR   Pfam; PF01687; Flavokinase; 1.
DR   ProDom; PD003662; FAD_Synth; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; FMN; Kinase; Magnesium; Metal-binding;
KW   Nucleotide-binding; Transferase; Zinc.
FT   CHAIN         1    205       Riboflavin kinase.
FT                                /FTId=PRO_0000301837.
FT   ACT_SITE    104    104       Nucleophile (By similarity).
FT   METAL        44     44       Magnesium or zinc (By similarity).
SQ   SEQUENCE   205 AA;  22385 MW;  655D3733D10B2371 CRC64;
     MRPDTSRDPV AGPDSGPEPP FPIRLAGPVI KGFGRGSKEL GIPTANIPAD GLAEYPDLQV
     GVYYGVVALN PAQSEVPSTS AQILPAVLSI GYNPFYKNTT RSIEIHIMPP LTAPSPTATG
     TPGHVTFHKL PDFYGTSLKL LILGYIRPEY DYVSAEALIE DIRVDCEVAR RSLQRGAYVR
     YLGAGADENE ENEEVQEQRR WLTTF
//