Reviewed, UniProtKB/Swiss-Prot Q0CHR1 (RIFK_ASPTN)

Names and origin

Protein names

Recommended name:
    Riboflavin kinase
    EC=2.7.1.26
Alternative name(s):
    Flavin mononucleotide kinase 1

Gene names

Name:	fmn1
ORF Names:	ATEG_06773

Organism

Aspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]

Taxonomic identifier

341663 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme By similarity.
Catalytic activity	ATP + riboflavin = ADP + FMN.
Cofactor	Zinc or magnesium By similarity.
Pathway	Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.
Sequence similarities	Belongs to the flavokinase family.

Ontologies

Keywords
Ligand	ATP-binding FMN Magnesium Metal-binding Nucleotide-binding Zinc
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	riboflavin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW riboflavin kinase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 205	205	Riboflavin kinase		PRO_0000301837
Sites
	Active site	104	1	Nucleophile By similarity
	Metal binding	44	1	Magnesium or zinc By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0CHR1-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 655D3733D10B2371	FASTA	205	22,385
	10 20 30 40 50 60 MRPDTSRDPV AGPDSGPEPP FPIRLAGPVI KGFGRGSKEL GIPTANIPAD GLAEYPDLQV 70 80 90 100 110 120 GVYYGVVALN PAQSEVPSTS AQILPAVLSI GYNPFYKNTT RSIEIHIMPP LTAPSPTATG 130 140 150 160 170 180 TPGHVTFHKL PDFYGTSLKL LILGYIRPEY DYVSAEALIE DIRVDCEVAR RSLQRGAYVR 190 200 YLGAGADENE ENEEVQEQRR WLTTF

References

[1]

"Annotation of the Aspergillus terreus NIH2624 genome." Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M., Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K. , Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J., Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W., Nierman W.C., Milne T., Madden K. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CH476602 Genomic DNA. Translation: EAU33317.1.
RefSeq	XP_001215951.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4321940.
Family and domain databases
InterPro	IPR015865. Riboflavin_kinase. [Graphical view]
Gene3D	G3DSA:2.40.30.30. Riboflavin_kinase. 1 hit.
PANTHER	PTHR22749. Riboflavin_kinase. 1 hit.
Pfam	PF01687. Flavokinase. 1 hit. [Graphical view]
ProDom	PD003662. FAD_Synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

RIFK_ASPTN

Accession

Primary (citable) accession number: Q0CHR1

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	October 17, 2006
Last modified:	June 16, 2009
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)