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Q0CHR1

- RIFK_ASPTN

UniProt

Q0CHR1 - RIFK_ASPTN

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Protein

Riboflavin kinase

Gene

fmn1

Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.By similarity

Catalytic activityi

ATP + riboflavin = ADP + FMN.

Cofactori

Zn2+By similarity, Mg2+By similarityNote: Zinc or magnesium.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi44 – 441Magnesium or zincBy similarity
Active sitei104 – 1041NucleophileBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. FMN biosynthetic process Source: UniProtKB-UniPathway
  2. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin kinase (EC:2.7.1.26)
Alternative name(s):
Flavin mononucleotide kinase 1
Gene namesi
Name:fmn1
ORF Names:ATEG_06773
OrganismiAspergillus terreus (strain NIH 2624 / FGSC A1156)
Taxonomic identifieri341663 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000007963: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 205205Riboflavin kinasePRO_0000301837Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi33178.CADATEAP00009371.

Structurei

3D structure databases

ProteinModelPortaliQ0CHR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the flavokinase family.Curated

Phylogenomic databases

eggNOGiCOG0196.
HOGENOMiHOG000260803.
OMAiINFDCEV.
OrthoDBiEOG7K3V05.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
InterProiIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0CHR1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPDTSRDPV AGPDSGPEPP FPIRLAGPVI KGFGRGSKEL GIPTANIPAD
60 70 80 90 100
GLAEYPDLQV GVYYGVVALN PAQSEVPSTS AQILPAVLSI GYNPFYKNTT
110 120 130 140 150
RSIEIHIMPP LTAPSPTATG TPGHVTFHKL PDFYGTSLKL LILGYIRPEY
160 170 180 190 200
DYVSAEALIE DIRVDCEVAR RSLQRGAYVR YLGAGADENE ENEEVQEQRR

WLTTF
Length:205
Mass (Da):22,385
Last modified:October 17, 2006 - v1
Checksum:i655D3733D10B2371
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476602 Genomic DNA. Translation: EAU33317.1.
RefSeqiXP_001215951.1. XM_001215951.1.

Genome annotation databases

EnsemblFungiiCADATEAT00009371; CADATEAP00009371; CADATEAG00009371.
GeneIDi4321940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476602 Genomic DNA. Translation: EAU33317.1 .
RefSeqi XP_001215951.1. XM_001215951.1.

3D structure databases

ProteinModelPortali Q0CHR1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 33178.CADATEAP00009371.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADATEAT00009371 ; CADATEAP00009371 ; CADATEAG00009371 .
GeneIDi 4321940.

Phylogenomic databases

eggNOGi COG0196.
HOGENOMi HOG000260803.
OMAi INFDCEV.
OrthoDBi EOG7K3V05.

Enzyme and pathway databases

UniPathwayi UPA00276 ; UER00406 .

Family and domain databases

Gene3Di 2.40.30.30. 1 hit.
InterProi IPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view ]
PANTHERi PTHR22749. PTHR22749. 1 hit.
Pfami PF01687. Flavokinase. 1 hit.
[Graphical view ]
SMARTi SM00904. Flavokinase. 1 hit.
[Graphical view ]
SUPFAMi SSF82114. SSF82114. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NIH 2624 / FGSC A1156.

Entry informationi

Entry nameiRIFK_ASPTN
AccessioniPrimary (citable) accession number: Q0CHR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 17, 2006
Last modified: November 26, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3