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Protein

Riboflavin kinase

Gene

fmn1

Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.By similarity

Catalytic activityi

ATP + riboflavin = ADP + FMN.

Cofactori

Zn2+By similarity, Mg2+By similarityNote: Zinc or magnesium.By similarity

Pathwayi: FMN biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes FMN from riboflavin (ATP route).
Proteins known to be involved in this subpathway in this organism are:
  1. Riboflavin kinase (fmn1)
This subpathway is part of the pathway FMN biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes FMN from riboflavin (ATP route), the pathway FMN biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi44Magnesium or zincBy similarity1
Active sitei104NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin kinase (EC:2.7.1.26)
Alternative name(s):
Flavin mononucleotide kinase 1
Gene namesi
Name:fmn1
ORF Names:ATEG_06773
OrganismiAspergillus terreus (strain NIH 2624 / FGSC A1156)
Taxonomic identifieri341663 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi

Organism-specific databases

EuPathDBiFungiDB:ATEG_06773

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003018371 – 205Riboflavin kinaseAdd BLAST205

Interactioni

Protein-protein interaction databases

STRINGi33178.CADATEAP00009371

Structurei

3D structure databases

ProteinModelPortaliQ0CHR1
SMRiQ0CHR1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the flavokinase family.Curated

Phylogenomic databases

HOGENOMiHOG000260803
OMAiSIEIHIM
OrthoDBiEOG092C5F1Q

Family and domain databases

Gene3Di2.40.30.30, 1 hit
InterProiView protein in InterPro
IPR023468 Riboflavin_kinase
IPR015865 Riboflavin_kinase_bac/euk
IPR023465 Riboflavin_kinase_dom_sf
PANTHERiPTHR22749 PTHR22749, 1 hit
PfamiView protein in Pfam
PF01687 Flavokinase, 1 hit
SMARTiView protein in SMART
SM00904 Flavokinase, 1 hit
SUPFAMiSSF82114 SSF82114, 1 hit

Sequencei

Sequence statusi: Complete.

Q0CHR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPDTSRDPV AGPDSGPEPP FPIRLAGPVI KGFGRGSKEL GIPTANIPAD
60 70 80 90 100
GLAEYPDLQV GVYYGVVALN PAQSEVPSTS AQILPAVLSI GYNPFYKNTT
110 120 130 140 150
RSIEIHIMPP LTAPSPTATG TPGHVTFHKL PDFYGTSLKL LILGYIRPEY
160 170 180 190 200
DYVSAEALIE DIRVDCEVAR RSLQRGAYVR YLGAGADENE ENEEVQEQRR

WLTTF
Length:205
Mass (Da):22,385
Last modified:October 17, 2006 - v1
Checksum:i655D3733D10B2371
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476602 Genomic DNA Translation: EAU33317.1
RefSeqiXP_001215951.1, XM_001215951.1

Genome annotation databases

EnsemblFungiiCADATEAT00009371; CADATEAP00009371; CADATEAG00009371
GeneIDi4321940

Entry informationi

Entry nameiRIFK_ASPTN
AccessioniPrimary (citable) accession number: Q0CHR1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 17, 2006
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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