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Q0CC84 (CELB_ASPTN) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable endo-beta-1,4-glucanase celB

Short name=Endoglucanase celB
EC=3.2.1.4
Alternative name(s):
Carboxymethylcellulase celB
Cellulase B
Gene names
Name:celB
ORF Names:ATEG_08700
OrganismAspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]
Taxonomic identifier341663 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length420 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates By similarity.

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 7 (cellulase C) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 420402Probable endo-beta-1,4-glucanase celB
PRO_0000395158

Sites

Active site2151Nucleophile By similarity
Active site2201Proton donor By similarity

Amino acid modifications

Glycosylation1181N-linked (GlcNAc...) Potential
Glycosylation2341N-linked (GlcNAc...) Potential
Glycosylation2931N-linked (GlcNAc...) Potential
Glycosylation3831N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q0CC84 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 9EF66065C2AE30E6

FASTA42045,371
        10         20         30         40         50         60 
MLRKLTPLAL ALLPLVAGQT IGETPEVHPK LPTWKCSNRH GCVKQDTSVV IDAATHWIHE 

        70         80         90        100        110        120 
KGGETSCTGS SGPNPNLCPD KETCAANCVI EGISDYANYG VQTKGSSMTL HQYLRDGNTT 

       130        140        150        160        170        180 
KSVSPRVYLL AEDGENYEML QLLNQEFTFD VDVSTLVCGM NGALYFSEMQ RDGGRSELNP 

       190        200        210        220        230        240 
AGAARGTGYC DAQCFNIPWI NGEANVEGAG ACCNEMDIWE ANARATGYTP HPCNITQLYE 

       250        260        270        280        290        300 
CSGAECEANG VCDKPGCGFN PYALGAHDFY GYDLEVDTTK PMTVVTQFYT KDNTTTGALV 

       310        320        330        340        350        360 
EIRRLYVQNG HVIQNAVVSV DGESVDSITA DYCADPSSAF NRLGGLQRMG EALGRGMVLA 

       370        380        390        400        410        420 
FSVWNDAGSF MSWLDGGNSG PCNATEGDPA LIEKLHPDTH VTFSNIRWGD IGSTYRGKRR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH476606 Genomic DNA. Translation: EAU30832.1.
RefSeqXP_001217286.1. XM_001217285.1.

3D structure databases

ProteinModelPortalQ0CC84.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING33178.CADATEAP00006976.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADATEAT00006976; CADATEAP00006976; CADATEAG00006976.
GeneID4323506.

Phylogenomic databases

eggNOGNOG138370.
HOGENOMHOG000182210.
OMAPWINGEA.
OrthoDBEOG7Q8CXJ.

Family and domain databases

Gene3D2.70.100.10. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR001722. Glyco_hydro_7.
[Graphical view]
PfamPF00840. Glyco_hydro_7. 1 hit.
[Graphical view]
PRINTSPR00734. GLHYDRLASE7.
SUPFAMSSF49899. SSF49899. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCELB_ASPTN
AccessionPrimary (citable) accession number: Q0CC84
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: October 17, 2006
Last modified: March 19, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries