Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q0C8Z0 (EXGB_ASPTN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glucan endo-1,6-beta-glucosidase B

EC=3.2.1.75
Alternative name(s):
Beta-1,6-glucanase B
Endo-1,6-beta-D-glucanase B
Endo-1,6-beta-glucanase B
Gene names
Name:exgB
ORF Names:ATEG_09844
OrganismAspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]
Taxonomic identifier341663 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides By similarity.

Catalytic activity

Random hydrolysis of (1->6)-linkages in (1->6)-beta-D-glucans.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cell wall biogenesis/degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpolysaccharide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucan endo-1,6-beta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 404384Probable glucan endo-1,6-beta-glucosidase B
PRO_0000394709

Sites

Active site2221Proton donor By similarity
Active site3241Nucleophile By similarity

Amino acid modifications

Glycosylation331N-linked (GlcNAc...) Potential
Glycosylation1301N-linked (GlcNAc...) Potential
Glycosylation2531N-linked (GlcNAc...) Potential
Glycosylation2991N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q0C8Z0 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 57FDB335BFFF69E8

FASTA40445,814
        10         20         30         40         50         60 
MTTYQTLFLI PLAISTLVTA WLPETDKTIT SRNGTNLFAS SKGKIRGVNM GSQFVFEPWI 

        70         80         90        100        110        120 
AEKAWSSMGC KGQKSEFDCV VSLGQDAANK AFAQHWGSWI TQDDITEIQS YTLNTIRVPI 

       130        140        150        160        170        180 
GYWMKEDLVN KTSEHFPQGG FAYLEKLCGW ASDAGLYIIL DLHGAPGAQT PHNPFTGQYA 

       190        200        210        220        230        240 
STAGFYNDYQ FGRALEFLEW ITTKVHQSDS FRNVGMLEIV NEPLQNAQKV GSMRSTYYPD 

       250        260        270        280        290        300 
AFKRIRAAEQ KLNVSKSGYL HIQMMDKLWG SGDPEEYLTD KYYVAYDDHR YLKWDPKVNV 

       310        320        330        340        350        360 
SKENYISTSC SDELDSNTPT IVGEWSLSVP DDVASTPDWD MDTNKDFYKK WFAAQITAYE 

       370        380        390        400 
KQRGWVFWTW KTQLGGYRWS YKDAVAAGVV PEDIDSALNM GVCN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH476608 Genomic DNA. Translation: EAU30035.1.
RefSeqXP_001218466.1. XM_001218465.1.

3D structure databases

ProteinModelPortalQ0C8Z0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADATEAT00003862; CADATEAP00003862; CADATEAG00003862.
GeneID4354491.

Phylogenomic databases

eggNOGCOG2730.
HOGENOMHOG000217590.
OMASEHFPQG.
OrthoDBEOG776T0C.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameEXGB_ASPTN
AccessionPrimary (citable) accession number: Q0C8Z0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: October 17, 2006
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries