Q0C8B3 (AXHA_ASPTN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable alpha-L-arabinofuranosidase axhA
EC=3.2.1.55

Alternative name(s):
Arabinoxylan arabinofuranohydrolase axhA

Gene names

Name:	axhA
ORF Names:	ATEG_10071

Organism

Aspergillus terreus (strain NIH 2624 / FGSC A1156) [Complete proteome]

Taxonomic identifier

341663 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus › Aspergillus terreus

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan By similarity.
Catalytic activity	Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the glycosyl hydrolase 62 family.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	L-arabinose metabolic process Inferred from electronic annotation. Source: InterPro xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	alpha-N-arabinofuranosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential
	Chain	25 – 326	302	Probable alpha-L-arabinofuranosidase axhA		PRO_0000393535
Amino acid modifications
	Glycosylation	307	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q0C8B3 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 9B391295A16C4943	FASTA	326	35,088
	10 20 30 40 50 60 MRPRQSKVTQ VLSGAVLLAS GAAASCSLPS TYSWTSTEAL AEPKSGWTAL KDFTNVVSNG 70 80 90 100 110 120 QHIVYASTTD SSGNYGSMAF SPFADWSDMA SASQNAMSAS AVAPTIFYFA PKDVWILAYQ 130 140 150 160 170 180 WGPTAFSYKT SSDPSDANGW SEAQPLFSGS ISDSSTGVID QTVIGDDTNM YLFFAGDNGR 190 200 210 220 230 240 IYRASMSIDN FPGDFGTQSE VVLEDTTNNL FEAVQVYKVD GQDQYLMIVE AIGSAGRYFR 250 260 270 280 290 300 SFTASSLDGE WTVQAGTEDQ PFAGKANSGA SWTNDISHGD LVRNNPDQTF TVDPCNLQLL 310 320 YQGKDPNSSG DYNQLAWRPG VLTLKV

References

[1]

"Annotation of the Aspergillus terreus NIH2624 genome." Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M., Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K. , Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J., Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W., Nierman W.C., Milne T., Madden K. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NIH 2624 / FGSC A1156.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH476609 Genomic DNA. Translation: EAU29520.1.
RefSeq	XP_001209373.1. XM_001209373.1.
3D structure databases
ProteinModelPortal	Q0C8B3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADATEAT00001980; CADATEAP00001980; CADATEAG00001980.
GeneID	4319554.
Phylogenomic databases
eggNOG	NOG81570.
HOGENOM	HOG000164911.
OrthoDB	EOG4XH383.
Family and domain databases
Gene3D	2.115.10.20. 1 hit.
InterPro	IPR005193. GH62_arabinosidase. IPR023296. Glyco_hydro_beta-prop. [Graphical view]
Pfam	PF03664. Glyco_hydro_62. 1 hit. [Graphical view]
SUPFAM	SSF75005. Glyco_hydro_43_beta-prop. 1 hit.
ProtoNet	Search...

Entry information

Entry name

AXHA_ASPTN

Accession

Primary (citable) accession number: Q0C8B3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 20, 2010
Last sequence update:	October 17, 2006
Last modified:	March 6, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program