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Protein

Probable beta-glucosidase M

Gene

bglM

Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).By similarity

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei303 – 3031By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00696.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable beta-glucosidase M (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase M
Cellobiase M
Gentiobiase M
Gene namesi
Name:bglM
ORF Names:ATEG_10320
OrganismiAspergillus terreus (strain NIH 2624 / FGSC A1156)
Taxonomic identifieri341663 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000007963 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ATEG_10320.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence AnalysisAdd
BLAST
Chaini20 – 782763Probable beta-glucosidase MPRO_0000394908Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi25 – 251N-linked (GlcNAc...)Sequence Analysis
Glycosylationi46 – 461N-linked (GlcNAc...)Sequence Analysis
Glycosylationi72 – 721N-linked (GlcNAc...)Sequence Analysis
Glycosylationi275 – 2751N-linked (GlcNAc...)Sequence Analysis
Glycosylationi331 – 3311N-linked (GlcNAc...)Sequence Analysis
Glycosylationi338 – 3381N-linked (GlcNAc...)Sequence Analysis
Glycosylationi443 – 4431N-linked (GlcNAc...)Sequence Analysis
Glycosylationi449 – 4491N-linked (GlcNAc...)Sequence Analysis
Glycosylationi536 – 5361N-linked (GlcNAc...)Sequence Analysis
Glycosylationi558 – 5581N-linked (GlcNAc...)Sequence Analysis
Glycosylationi654 – 6541N-linked (GlcNAc...)Sequence Analysis
Glycosylationi664 – 6641N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi33178.CADATEAP00001433.

Structurei

3D structure databases

ProteinModelPortaliQ0C7L4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG1472.
HOGENOMiHOG000031215.
OMAiNITPQFE.
OrthoDBiEOG7HMS8F.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0C7L4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSFLGLVGL LAGVSVSSAA PSVQNITSDT YFYGQSPPVY PSPEGNGTGS
60 70 80 90 100
WAVAYQKAKA FVAQLTSEEK VNLTAGVTSD TGCSGMIPAI PRLNFPGLCV
110 120 130 140 150
SDAGDGLRGT DYVNSWPSGI HAGASWNKNL ARQRAYHMGT EFHKKGVNVL
160 170 180 190 200
LGPVVAPLGR VVEGGRNWEG FSNDPYLSGA LVYETVKGIQ SAGVGACTKV
210 220 230 240 250
RFPQRLQSSG SNLVQHFTGY EQETNRNPET VDGVDIASVS SNIDDKAMHE
260 270 280 290 300
LYLWPFQDAV HAGSVSVMCS YQRINNSYAC QNSKTLNGLL KTELGFQGYV
310 320 330 340 350
MTDWYGQHGG IAAANAGLDM VMPYTELWGS NLTDAISNGT MEASRLDDMA
360 370 380 390 400
TRIIASWYQV NQNKNFPAPG IGMPADVNEP HQAVIGKSPD SRTTLLQGAI
410 420 430 440 450
EGHVLVKNTK QALPLQSPRL LSVFGYDAKA GDSLIVNDVS FVNASVQKNH
460 470 480 490 500
TLYVGGGSGT NSAAYVLAPL DAVQQQAYED GTSVLWDVVS EDPDVDATTD
510 520 530 540 550
ACLVFINAYA TEGYDRPGLV NKESDTLITN VAGKCNNTIV TIHNAGIRLV
560 570 580 590 600
GDWINHENVT AVIFAHLPGQ DTGKALVELL YGRANPSGRL PYTVAKRAGD
610 620 630 640 650
YGSLLHPSQP EGKYGLFPQS DFSEGVFIDY RAFDKQGIEP QFEFGFGLSY
660 670 680 690 700
TSFNYSGLAV KKVNRTTEPY PASAPVQEGG NPNLWDEILT VSAKVQNSGS
710 720 730 740 750
MDGDEVAQLY LGIPNAPVRQ LRGFEKVGIP AGQAVNVKFS LTRRDLSVWD
760 770 780
TEAQQWKLQS GDYQVYVGRS SRDLPLKGQF SI
Length:782
Mass (Da):84,156
Last modified:October 17, 2006 - v1
Checksum:i9A643E8C0562AB5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476610 Genomic DNA. Translation: EAU29317.1.
RefSeqiXP_001218668.1. XM_001218667.1.

Genome annotation databases

EnsemblFungiiCADATEAT00001433; CADATEAP00001433; CADATEAG00001433.
GeneIDi4354713.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476610 Genomic DNA. Translation: EAU29317.1.
RefSeqiXP_001218668.1. XM_001218667.1.

3D structure databases

ProteinModelPortaliQ0C7L4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi33178.CADATEAP00001433.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADATEAT00001433; CADATEAP00001433; CADATEAG00001433.
GeneIDi4354713.

Organism-specific databases

EuPathDBiFungiDB:ATEG_10320.

Phylogenomic databases

eggNOGiCOG1472.
HOGENOMiHOG000031215.
OMAiNITPQFE.
OrthoDBiEOG7HMS8F.

Enzyme and pathway databases

UniPathwayiUPA00696.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NIH 2624 / FGSC A1156.

Entry informationi

Entry nameiBGLM_ASPTN
AccessioniPrimary (citable) accession number: Q0C7L4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: October 17, 2006
Last modified: April 29, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.