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Protein

Probable beta-glucosidase M

Gene

bglM

Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).By similarity

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathwayi: cellulose degradation

This protein is involved in the pathway cellulose degradation, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway cellulose degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei303By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00696.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable beta-glucosidase M (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase M
Cellobiase M
Gentiobiase M
Gene namesi
Name:bglM
ORF Names:ATEG_10320
OrganismiAspergillus terreus (strain NIH 2624 / FGSC A1156)
Taxonomic identifieri341663 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000007963 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ATEG_10320.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000039490820 – 782Probable beta-glucosidase MAdd BLAST763

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi25N-linked (GlcNAc...)Sequence analysis1
Glycosylationi46N-linked (GlcNAc...)Sequence analysis1
Glycosylationi72N-linked (GlcNAc...)Sequence analysis1
Glycosylationi275N-linked (GlcNAc...)Sequence analysis1
Glycosylationi331N-linked (GlcNAc...)Sequence analysis1
Glycosylationi338N-linked (GlcNAc...)Sequence analysis1
Glycosylationi443N-linked (GlcNAc...)Sequence analysis1
Glycosylationi449N-linked (GlcNAc...)Sequence analysis1
Glycosylationi536N-linked (GlcNAc...)Sequence analysis1
Glycosylationi558N-linked (GlcNAc...)Sequence analysis1
Glycosylationi654N-linked (GlcNAc...)Sequence analysis1
Glycosylationi664N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ0C7L4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000031215.
OMAiNITPQFE.
OrthoDBiEOG092C0ZJY.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 2 hits.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SMARTiSM01217. Fn3_like. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0C7L4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSFLGLVGL LAGVSVSSAA PSVQNITSDT YFYGQSPPVY PSPEGNGTGS
60 70 80 90 100
WAVAYQKAKA FVAQLTSEEK VNLTAGVTSD TGCSGMIPAI PRLNFPGLCV
110 120 130 140 150
SDAGDGLRGT DYVNSWPSGI HAGASWNKNL ARQRAYHMGT EFHKKGVNVL
160 170 180 190 200
LGPVVAPLGR VVEGGRNWEG FSNDPYLSGA LVYETVKGIQ SAGVGACTKV
210 220 230 240 250
RFPQRLQSSG SNLVQHFTGY EQETNRNPET VDGVDIASVS SNIDDKAMHE
260 270 280 290 300
LYLWPFQDAV HAGSVSVMCS YQRINNSYAC QNSKTLNGLL KTELGFQGYV
310 320 330 340 350
MTDWYGQHGG IAAANAGLDM VMPYTELWGS NLTDAISNGT MEASRLDDMA
360 370 380 390 400
TRIIASWYQV NQNKNFPAPG IGMPADVNEP HQAVIGKSPD SRTTLLQGAI
410 420 430 440 450
EGHVLVKNTK QALPLQSPRL LSVFGYDAKA GDSLIVNDVS FVNASVQKNH
460 470 480 490 500
TLYVGGGSGT NSAAYVLAPL DAVQQQAYED GTSVLWDVVS EDPDVDATTD
510 520 530 540 550
ACLVFINAYA TEGYDRPGLV NKESDTLITN VAGKCNNTIV TIHNAGIRLV
560 570 580 590 600
GDWINHENVT AVIFAHLPGQ DTGKALVELL YGRANPSGRL PYTVAKRAGD
610 620 630 640 650
YGSLLHPSQP EGKYGLFPQS DFSEGVFIDY RAFDKQGIEP QFEFGFGLSY
660 670 680 690 700
TSFNYSGLAV KKVNRTTEPY PASAPVQEGG NPNLWDEILT VSAKVQNSGS
710 720 730 740 750
MDGDEVAQLY LGIPNAPVRQ LRGFEKVGIP AGQAVNVKFS LTRRDLSVWD
760 770 780
TEAQQWKLQS GDYQVYVGRS SRDLPLKGQF SI
Length:782
Mass (Da):84,156
Last modified:October 17, 2006 - v1
Checksum:i9A643E8C0562AB5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476610 Genomic DNA. Translation: EAU29317.1.
RefSeqiXP_001218668.1. XM_001218667.1.

Genome annotation databases

EnsemblFungiiCADATEAT00001433; CADATEAP00001433; CADATEAG00001433.
GeneIDi4354713.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476610 Genomic DNA. Translation: EAU29317.1.
RefSeqiXP_001218668.1. XM_001218667.1.

3D structure databases

ProteinModelPortaliQ0C7L4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADATEAT00001433; CADATEAP00001433; CADATEAG00001433.
GeneIDi4354713.

Organism-specific databases

EuPathDBiFungiDB:ATEG_10320.

Phylogenomic databases

HOGENOMiHOG000031215.
OMAiNITPQFE.
OrthoDBiEOG092C0ZJY.

Enzyme and pathway databases

UniPathwayiUPA00696.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 2 hits.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SMARTiSM01217. Fn3_like. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiBGLM_ASPTN
AccessioniPrimary (citable) accession number: Q0C7L4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: October 17, 2006
Last modified: September 7, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.