Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q0C4U8

- TRUA_HYPNA

UniProt

Q0C4U8 - TRUA_HYPNA

Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Hyphomonas neptunium (strain ATCC 15444)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (17 Oct 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei52 – 521NucleophileUniRule annotation
    Binding sitei110 – 1101SubstrateUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    tRNA processing

    Enzyme and pathway databases

    BioCyciHNEP228405:GI69-515-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(38-40) synthaseUniRule annotation
    tRNA pseudouridylate synthase IUniRule annotation
    tRNA-uridine isomerase IUniRule annotation
    Gene namesi
    Name:truAUniRule annotation
    Ordered Locus Names:HNE_0515
    OrganismiHyphomonas neptunium (strain ATCC 15444)
    Taxonomic identifieri228405 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeHyphomonas
    ProteomesiUP000001959: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 247247tRNA pseudouridine synthase APRO_1000017094Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi228405.HNE_0515.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0C4U8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0101.
    HOGENOMiHOG000248672.
    KOiK06173.
    OMAiWDPFRLS.
    OrthoDBiEOG6Z9B4R.

    Family and domain databases

    Gene3Di3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPiMF_00171. TruA.
    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view]
    PANTHERiPTHR11142. PTHR11142. 1 hit.
    PfamiPF01416. PseudoU_synth_1. 2 hits.
    [Graphical view]
    PIRSFiPIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00071. hisT_truA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0C4U8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRYRLLIEY NGGPYQGWMR LPGLQTVQGA LEAAAAQLDG GPVEVTGAGR    50
    TDAGVHATGQ VAHMDLRVDR PNKVADAMNY HLRPHPIAVL KADRVEEDFH 100
    ARFSAIARHY RYIVINRRAH LTHDQGLAWR VPSRLDADKM HEAAQSFVGT 150
    HDFTTFRDSE CQALSPVKTL TRLDVARYND RIEFTCSAPS FIHRQVRSLV 200
    GSLVEVGRGR HPVKWAREIL EAADRTRCGP VAPSDGLFLE RVDYPAG 247
    Length:247
    Mass (Da):27,597
    Last modified:October 17, 2006 - v1
    Checksum:iC0568A7A54460946
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000158 Genomic DNA. Translation: ABI76878.1.
    RefSeqiYP_759245.1. NC_008358.1.

    Genome annotation databases

    EnsemblBacteriaiABI76878; ABI76878; HNE_0515.
    GeneIDi4289509.
    KEGGihne:HNE_0515.
    PATRICi32213822. VBIHypNep17450_0516.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000158 Genomic DNA. Translation: ABI76878.1 .
    RefSeqi YP_759245.1. NC_008358.1.

    3D structure databases

    ProteinModelPortali Q0C4U8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 228405.HNE_0515.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABI76878 ; ABI76878 ; HNE_0515 .
    GeneIDi 4289509.
    KEGGi hne:HNE_0515.
    PATRICi 32213822. VBIHypNep17450_0516.

    Phylogenomic databases

    eggNOGi COG0101.
    HOGENOMi HOG000248672.
    KOi K06173.
    OMAi WDPFRLS.
    OrthoDBi EOG6Z9B4R.

    Enzyme and pathway databases

    BioCyci HNEP228405:GI69-515-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPi MF_00171. TruA.
    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view ]
    PANTHERi PTHR11142. PTHR11142. 1 hit.
    Pfami PF01416. PseudoU_synth_1. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00071. hisT_truA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15444.

    Entry informationi

    Entry nameiTRUA_HYPNA
    AccessioniPrimary (citable) accession number: Q0C4U8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3