Q0C490 (Q0C490_HYPNA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alanine racemase EMBL ABI76247.1
EC=5.1.1.1 EMBL ABI76247.1

Gene names

Ordered Locus Names:

HNE_0725

Organism

Hyphomonas neptunium (strain ATCC 15444) [Complete proteome] [HAMAP] EMBL ABI76247.1

Taxonomic identifier

228405 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Hyphomonadaceae › Hyphomonas › Hyphomonas neptunium

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608 EMBL ABI76247.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0C490 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: B971162725F6DEF1	FASTA	351	37,173
	10 20 30 40 50 60 MSQMPRATVL TGNIADNWRT LDALHPGATT AAVVKADAYG LGAMRVARAL RIAGCQTFFV 70 80 90 100 110 120 AYAEEGLIVR KAAGKAARIF VLNGPVRSEM ATYRDADLTA VLSSEAHVKL WGTAPKGSCA 130 140 150 160 170 180 LHFDTGMNRL GLPMDMSEKD LAALRRLQPV LIMSHLACAD DPENPANTAQ RKAFNEISDA 190 200 210 220 230 240 FPDTPASLAN SNGCYLGKGF AYDLTRPGLA LYGGTTPPEK VKLKPGVILE ASILATFSGQ 250 260 270 280 290 300 TGTKVGYGGT HTLPEDRILA TCALGYADGI PRAGANQITG WLEGNPCPVL GRISMDLITL 310 320 330 340 350 DVTDCVKHAK PGARVEFLGE NAKLEVQAAA CGTLGYELLT GLGPRVQRVY R

References

[1]

"Comparative genomic evidence for a close relationship between the dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter crescentus." Badger J.H., Hoover T.R., Brun Y.V., Weiner R.M., Laub M.T., Alexandre G., Mrazek J., Ren Q., Paulsen I.T., Nelson K.E., Khouri H.M., Radune D., Sosa J., Dodson R.J., Sullivan S.A., Rosovitz M.J., Madupu R., Brinkac L.M. , Durkin A.S., Daugherty S.C., Kothari S.P., Giglio M.G., Zhou L., Haft D.H., Selengut J.D., Davidsen T.M., Yang Q., Zafar N., Ward N.L. J. Bacteriol. 188:6841-6850(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15444.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000158 Genomic DNA. Translation: ABI76247.1.
RefSeq	YP_759453.1. NC_008358.1.
3D structure databases
ProteinModelPortal	Q0C490.
ModBase	Search...
Protein-protein interaction databases
STRING	228405.HNE_0725.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABI76247; ABI76247; HNE_0725.
GeneID	4289560.
KEGG	hne:HNE_0725.
PATRIC	32214258. VBIHypNep17450_0732.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0787.
HOGENOM	HOG000031445.
KO	K01775.
Enzyme and pathway databases
BioCyc	HNEP228405:GI69-767-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0C490_HYPNA

Accession

Primary (citable) accession number: Q0C490

Entry history

Integrated into UniProtKB/TrEMBL:	October 17, 2006
Last sequence update:	October 17, 2006
Last modified:	May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)