Reviewed, UniProtKB/Swiss-Prot Q0C438 (CYSD_HYPNA)

Names and origin

Protein names

Recommended name:
    Sulfate adenylyltransferase subunit 2
    EC=2.7.7.4
Alternative name(s):
    Sulfate adenylate transferase
      Short name=SAT
    ATP-sulfurylase small subunit

Gene names

Name:	cysD
Ordered Locus Names:	HNE_0777

Organism

Hyphomonas neptunium (strain ATCC 15444) [Complete proteome] [HAMAP]

Taxonomic identifier

228405 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Hyphomonadaceae › Hyphomonas

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of cysD, the smaller subunit, and cysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: HAMAP sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_0000340197

Sequences

	Sequence		Length	Mass (Da)
	Q0C438-1 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 042F0C503BB1AA0A	FASTA	328	37,535
	10 20 30 40 50 60 MRTRHGAFLL LARPATERAH TPEQDQYTLP TLTHLDRLEA ESLHILREVA AECEKPVMLY 70 80 90 100 110 120 SIGKDSAVML HLAMKAFYPA RPPFPLLHVD TGWKFREMIA FRDRKVKELG LELLVHMNED 130 140 150 160 170 180 GVREGVGPFT HGSAYHTDVM KTAALKQALD KYGFDAAFGG ARRDEEKSRA KERVISFRSA 190 200 210 220 230 240 GHRWDPKRQR PEIWNLYNTR MHKGESLRAF PLSNWTELDI WQYIRREGIE LVPLYLAAPR 250 260 270 280 290 300 PVVTWNDTLI MVDDDRVPAE IAAKAEVKSV RFRTLGCYPL TGAVESTATT LDDVIQEILL 310 320 TTTSERQGRA IDKDQTASME KKKQEGYF

References

[1]

"Comparative genomic evidence for a close relationship between the dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter crescentus." Badger J.H., Hoover T.R., Brun Y.V., Weiner R.M., Laub M.T., Alexandre G., Mrazek J., Ren Q., Paulsen I.T., Nelson K.E., Khouri H.M., Radune D., Sosa J., Dodson R.J., Sullivan S.A., Rosovitz M.J., Madupu R., Brinkac L.M. , Durkin A.S., Daugherty S.C., Kothari S.P., Giglio M.G., Zhou L., Haft D.H., Selengut J.D., Davidsen T.M., Yang Q., Zafar N., Ward N.L. J. Bacteriol. 188:6841-6850(2006) [PubMed: 16980487] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000158 Genomic DNA. Translation: ABI77512.1.
RefSeq	YP_759505.1.
3D structure databases
SMR	Q0C438. Positions 32-238.
ModBase	Search...
Genome annotation databases
GeneID	4289582.
GenomeReviews	Gene locus HNE_0777 in contig CP000158_GR.
KEGG	hne:HNE_0777.
NMPDR	fig|228405.5.peg.760.
TIGR	HNE_0777.
Phylogenomic databases
HOGENOM	Q0C438.
OMA	Q0C438. AKERVIS.
Enzyme and pathway databases
BioCyc	HNEP81032:HNE_0777-MON.
Family and domain databases
HAMAP	MF_00064. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_HYPNA

Accession

Primary (citable) accession number: Q0C438

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	October 17, 2006
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)