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Q0C3J7 (Q0C3J7_HYPNA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183
Gene names
Name:ald EMBL ABI76118.1
Ordered Locus Names:HNE_0971
OrganismHyphomonas neptunium (strain ATCC 15444) [Complete proteome] [HAMAP] EMBL ABI76118.1
Taxonomic identifier228405 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Hyphomonadaceae › Hyphomonas

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183

Pathway

Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183

Sequence similarities

Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
   LigandNAD PIRNR PIRNR000183
   Molecular functionOxidoreductase PIRNR PIRNR000183 EMBL ABI76118.1
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalanine dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q0C3J7 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: 42A04EF7B4FB5199

FASTA37339,309
        10         20         30         40         50         60 
MRIGVPTEIK KQESRVGLTP ESAGELVRAG HQVNIQAGAG IASGFADETY TAIGAAILPD 

        70         80         90        100        110        120 
AEALFAQSDL IVKVKEPQPE ETARLTKDHT LFTYLHLAPD PVQAKGLMNS GCLAIAYETV 

       130        140        150        160        170        180 
TDAHGGLPLL RPMSQVAGRM SMQVAAGALM RTKGRGRGIL LGGVPGVAPA KVVIIGGGVS 

       190        200        210        220        230        240 
GTHAAEIAVG MRADVWVFDR NNERLGELDE QFRGTINTMY STAHSLAEAI KDADLVIGAV 

       250        260        270        280        290        300 
LIPGASAPKL VSRAQLSTMQ PGSVLVDIAI DQGGCFETSR PTTHDDPIYE VDGILHYCVA 

       310        320        330        340        350        360 
NMPGAVPRTS TYALNNATLP FVMQIANLGA RNAINANKHL ANGLTADQGT IAHKLVARDL 

       370 
GEKYVRPDWL TVV

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References

[1]"Comparative genomic evidence for a close relationship between the dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter crescentus."
Badger J.H., Hoover T.R., Brun Y.V., Weiner R.M., Laub M.T., Alexandre G., Mrazek J., Ren Q., Paulsen I.T., Nelson K.E., Khouri H.M., Radune D., Sosa J., Dodson R.J., Sullivan S.A., Rosovitz M.J., Madupu R., Brinkac L.M. expand/collapse author list , Durkin A.S., Daugherty S.C., Kothari S.P., Giglio M.G., Zhou L., Haft D.H., Selengut J.D., Davidsen T.M., Yang Q., Zafar N., Ward N.L.
J. Bacteriol. 188:6841-6850(2006) [PubMed: 16980487] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000158 Genomic DNA. Translation: ABI76118.1.
RefSeqYP_759696.1. NC_008358.1.

3D structure databases

ProteinModelPortalQ0C3J7.
SMRQ0C3J7. Positions 1-370.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0C3J7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4288472.
GenomeReviewsGene locus HNE_0971 in contig CP000158_GR.
KEGGhne:HNE_0971.
NMPDRfig|228405.5.peg.948.
PATRIC32214747. VBIHypNep17450_0975.
TIGRHNE_0971.

Phylogenomic databases

eggNOGCOG0686.
HOGENOMHBG289735.
OMAAIGYETV.
ProtClustDBCLSK777649.

Family and domain databases

InterProIPR008141. Ala_DH/Pyr_transHydgase.
IPR007886. AlaDH/PNT_N.
IPR007698. AlaDH/PNT_NAD(H)-bd.
[Graphical view]
KOK00259.
PANTHERPTHR10160:SF3. PTHR10160:SF3. 1 hit.
PfamPF01262. AlaDh_PNT_C. 1 hit.
PF05222. AlaDh_PNT_N. 1 hit.
[Graphical view]
PIRSFPIRSF000183. Alanine_dh. 1 hit.
SMARTSM01002. AlaDh_PNT_C. 1 hit.
SM01003. AlaDh_PNT_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00518. AlaDH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ0C3J7_HYPNA
AccessionPrimary (citable) accession number: Q0C3J7
Entry history
Integrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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