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Q0C093

- KGUA_HYPNA

UniProt

Q0C093 - KGUA_HYPNA

Protein

Guanylate kinase

Gene

gmk

Organism
Hyphomonas neptunium (strain ATCC 15444)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (17 Oct 2006)
      Previous versions | rss
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    Functioni

    Essential for recycling GMP and indirectly, cGMP.UniRule annotation

    Catalytic activityi

    ATP + GMP = ADP + GDP.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi22 – 298ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. guanylate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. purine nucleotide metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciHNEP228405:GI69-2154-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
    Alternative name(s):
    GMP kinaseUniRule annotation
    Gene namesi
    Name:gmkUniRule annotation
    Ordered Locus Names:HNE_2153
    OrganismiHyphomonas neptunium (strain ATCC 15444)
    Taxonomic identifieri228405 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeHyphomonas
    ProteomesiUP000001959: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 217217Guanylate kinasePRO_0000266336Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi228405.HNE_2153.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0C093.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini15 – 194180Guanylate kinase-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the guanylate kinase family.UniRule annotation
    Contains 1 guanylate kinase-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0194.
    HOGENOMiHOG000037638.
    KOiK00942.
    OMAiAGDLLEW.
    OrthoDBiEOG6CP410.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    HAMAPiMF_00328. Guanylate_kinase.
    InterProiIPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00625. Guanylate_kin. 1 hit.
    [Graphical view]
    SMARTiSM00072. GuKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
    PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q0C093-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNSGHPKDR GNRRGLMLVL SSPSGAGKTT LSRMLLEEFG DVKLSISATT    50
    RPPRPNEVHG EDYYFKTPDE FHRMIERREF LEWAHVFDKH YGTPKADTVA 100
    RLEAGEDVLF DVDWQGADAL HDQMPNDVVS VFILPPSIEA LQARLMGRPG 150
    STPELVARRM EDAKREIMHW RRYDYVIVND DLNVAYQRLK RILLVERLKR 200
    LRQIDLEDHV RALLGEA 217
    Length:217
    Mass (Da):25,018
    Last modified:October 17, 2006 - v1
    Checksum:i8836A35152B92D60
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000158 Genomic DNA. Translation: ABI76925.1.
    RefSeqiYP_760850.1. NC_008358.1.

    Genome annotation databases

    EnsemblBacteriaiABI76925; ABI76925; HNE_2153.
    GeneIDi4289885.
    KEGGihne:HNE_2153.
    PATRICi32217153. VBIHypNep17450_2160.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000158 Genomic DNA. Translation: ABI76925.1 .
    RefSeqi YP_760850.1. NC_008358.1.

    3D structure databases

    ProteinModelPortali Q0C093.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 228405.HNE_2153.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABI76925 ; ABI76925 ; HNE_2153 .
    GeneIDi 4289885.
    KEGGi hne:HNE_2153.
    PATRICi 32217153. VBIHypNep17450_2160.

    Phylogenomic databases

    eggNOGi COG0194.
    HOGENOMi HOG000037638.
    KOi K00942.
    OMAi AGDLLEW.
    OrthoDBi EOG6CP410.

    Enzyme and pathway databases

    BioCyci HNEP228405:GI69-2154-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    HAMAPi MF_00328. Guanylate_kinase.
    InterProi IPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00625. Guanylate_kin. 1 hit.
    [Graphical view ]
    SMARTi SM00072. GuKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
    PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15444.

    Entry informationi

    Entry nameiKGUA_HYPNA
    AccessioniPrimary (citable) accession number: Q0C093
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3