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Q0BZZ7

- LFTR_HYPNA

UniProt

Q0BZZ7 - LFTR_HYPNA

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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Hyphomonas neptunium (strain ATCC 15444)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciHNEP228405:GI69-2252-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:HNE_2251
OrganismiHyphomonas neptunium (strain ATCC 15444)
Taxonomic identifieri228405 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeHyphomonas
ProteomesiUP000001959: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 258258Leucyl/phenylalanyl-tRNA--protein transferasePRO_0000304338Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi228405.HNE_2251.

Structurei

3D structure databases

ProteinModelPortaliQ0BZZ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102326.
KOiK00684.
OMAiWISHEIM.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0BZZ7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSARFGPEDL LACYRRGVFP MADSRDDPRL FLVDPDFRGI LPLDAFHIPK
60 70 80 90 100
RLKRRVCQDP YRVSFDTAFT RVVEACGEPH DNRPNTWINS PIVNLYSALH
110 120 130 140 150
RQGFAHSVEC WDGDQLVGGL YGVSLGGAFF GESMFSRATD ASKIALVHLA
160 170 180 190 200
ARLIDRGYVL LDAQFHNPHL TQFGLIEISR DAFKARLKAA LKVGADFHGG
210 220 230 240 250
SDGPAPDQSI GMSSSGGVSD SVTPAGMSSY SGSSLSGMIA RSGSFTGSGA

VQRITQMS
Length:258
Mass (Da):27,891
Last modified:October 17, 2006 - v1
Checksum:iE542300D132BE62D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000158 Genomic DNA. Translation: ABI75713.1.
RefSeqiWP_011647244.1. NC_008358.1.
YP_760946.1. NC_008358.1.

Genome annotation databases

EnsemblBacteriaiABI75713; ABI75713; HNE_2251.
GeneIDi4287680.
KEGGihne:HNE_2251.
PATRICi32217349. VBIHypNep17450_2257.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000158 Genomic DNA. Translation: ABI75713.1 .
RefSeqi WP_011647244.1. NC_008358.1.
YP_760946.1. NC_008358.1.

3D structure databases

ProteinModelPortali Q0BZZ7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 228405.HNE_2251.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI75713 ; ABI75713 ; HNE_2251 .
GeneIDi 4287680.
KEGGi hne:HNE_2251.
PATRICi 32217349. VBIHypNep17450_2257.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102326.
KOi K00684.
OMAi WISHEIM.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci HNEP228405:GI69-2252-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15444.

Entry informationi

Entry nameiLFTR_HYPNA
AccessioniPrimary (citable) accession number: Q0BZZ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 17, 2006
Last modified: November 26, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3