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Q0BZZ7

- LFTR_HYPNA

UniProt

Q0BZZ7 - LFTR_HYPNA

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Protein
Leucyl/phenylalanyl-tRNA--protein transferase
Gene
aat, HNE_2251
Organism
Hyphomonas neptunium (strain ATCC 15444)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciHNEP228405:GI69-2252-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase (EC:2.3.2.6)
Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase
Gene namesi
Name:aat
Ordered Locus Names:HNE_2251
OrganismiHyphomonas neptunium (strain ATCC 15444)
Taxonomic identifieri228405 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeHyphomonas
ProteomesiUP000001959: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 258258Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation
PRO_0000304338Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi228405.HNE_2251.

Structurei

3D structure databases

ProteinModelPortaliQ0BZZ7.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102326.
KOiK00684.
OMAiWISHEIM.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0BZZ7-1 [UniParc]FASTAAdd to Basket

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MSARFGPEDL LACYRRGVFP MADSRDDPRL FLVDPDFRGI LPLDAFHIPK    50
RLKRRVCQDP YRVSFDTAFT RVVEACGEPH DNRPNTWINS PIVNLYSALH 100
RQGFAHSVEC WDGDQLVGGL YGVSLGGAFF GESMFSRATD ASKIALVHLA 150
ARLIDRGYVL LDAQFHNPHL TQFGLIEISR DAFKARLKAA LKVGADFHGG 200
SDGPAPDQSI GMSSSGGVSD SVTPAGMSSY SGSSLSGMIA RSGSFTGSGA 250
VQRITQMS 258
Length:258
Mass (Da):27,891
Last modified:October 17, 2006 - v1
Checksum:iE542300D132BE62D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000158 Genomic DNA. Translation: ABI75713.1.
RefSeqiYP_760946.1. NC_008358.1.

Genome annotation databases

EnsemblBacteriaiABI75713; ABI75713; HNE_2251.
GeneIDi4287680.
KEGGihne:HNE_2251.
PATRICi32217349. VBIHypNep17450_2257.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000158 Genomic DNA. Translation: ABI75713.1 .
RefSeqi YP_760946.1. NC_008358.1.

3D structure databases

ProteinModelPortali Q0BZZ7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 228405.HNE_2251.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI75713 ; ABI75713 ; HNE_2251 .
GeneIDi 4287680.
KEGGi hne:HNE_2251.
PATRICi 32217349. VBIHypNep17450_2257.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102326.
KOi K00684.
OMAi WISHEIM.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci HNEP228405:GI69-2252-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15444.

Entry informationi

Entry nameiLFTR_HYPNA
AccessioniPrimary (citable) accession number: Q0BZZ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 17, 2006
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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