Q0BZD2 (Q0BZD2_HYPNA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	HNE_2466

Organism

Hyphomonas neptunium (strain ATCC 15444) [Complete proteome] [HAMAP] EMBL ABI77284.1

Taxonomic identifier

228405 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Hyphomonadaceae › Hyphomonas

Protein attributes

Sequence length	1087 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0BZD2 [UniParc]. Last modified October 17, 2006. Version 1. Checksum: 15ACB8428A987A9D	FASTA	1,087	120,896
	10 20 30 40 50 60 MTAYAELAVT TNFSFLQGAS HAHELVRRAA DLGHVAIGIA DRNTLAGVVR AHVAAKEAGL 70 80 90 100 110 120 RLLVGARLVP ADGPEIIAYP MNRAAYGRLS RLLSKGKMRA AKGECHITVS DILKASEGQI 130 140 150 160 170 180 FIVMPPEALC LPFGRTLDEI ARAAPGRTYL AARYTYSGRN RERIFRLAEL AARAGVALMA 190 200 210 220 230 240 TNDVLYHAPE RRPLQDVLTC IREHHTLDTA GFLLEANGER HLKGGAEMAR LFKGFESSVA 250 260 270 280 290 300 RTVEISERCR FSLDELAYEY PDEPVPPGST PQEHLERLTW EGASGRYPGG VPEKVERQIR 310 320 330 340 350 360 DELRIIDQLS YAPYFLTVND IVQWARSQNI LCQGRGSAAN SAICYCLGIT SIDPTLTKLL 370 380 390 400 410 420 FARFLSPERK EPPDIDVDFE HERREEVIQY VYRRYGQHRA ALTATVISYR SRSAIREVCK 430 440 450 460 470 480 ALGLSDDISA ALANGVWGSW SDTLPDNRIA EAGLDPANPL IRRAVQLARQ LLGFPRHLSQ 490 500 510 520 530 540 HVGGFVLTRG DLIETVPIGN AAMRDRTFIE WDKDDIDALG IMKVDVLSLG MLTCIRKAFD 550 560 570 580 590 600 LLTEHKNTLH TLASVEQEDR ATYDMLCKGD SIGVFQVESR AQMAMLPRLR PRTYYDLVIE 610 620 630 640 650 660 VAIVRPGPIQ GNMVHPYLRR RKGIEAVSYP RPSPDQGPPD ELESILSRTL GVPLFQEQAM 670 680 690 700 710 720 QIAIDAARFS ADEANGLRRA MATFRNVGTI HQYEEMLVSN LIKRGYDPVF AKSCFDQIKG 730 740 750 760 770 780 FGEYGFPESH AASFALLVYV SSWIKCHHPD VFCAALLNSQ PMGFYAPAQI VRDAQAHGVE 790 800 810 820 830 840 VRPVDVNYSD WDNILEPDER ASGSFAVRLG FRQVDGLNRE DMERLMVRRG TGYETPDRLM 850 860 870 880 890 900 QHAQLTRSVL ERLAAADAFG SMSLTRREAL WKVRGEAPQQ TLPLFATAGL SEQGSETGIT 910 920 930 940 950 960 LPVIPPSEHV IQDYQTTGLS LKGHPMHFLR SLHARRGVLS THDAARLPNG CRVQTSGIVL 970 980 990 1000 1010 1020 VRQRPGTASG VVFITLEDET GIANLVVWPR VMERFRTVVM RSRIIQVKGR VQTAENVTHI 1030 1040 1050 1060 1070 1080 VAEQLIDCTS ELNLLTEDML RDPLKGALAR PDEVARPVPE RDGPPKRMAG DGHPRNVRVI PPSRDFH

References

[1]

"Comparative genomic evidence for a close relationship between the dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter crescentus." Badger J.H., Hoover T.R., Brun Y.V., Weiner R.M., Laub M.T., Alexandre G., Mrazek J., Ren Q., Paulsen I.T., Nelson K.E., Khouri H.M., Radune D., Sosa J., Dodson R.J., Sullivan S.A., Rosovitz M.J., Madupu R., Brinkac L.M. , Durkin A.S., Daugherty S.C., Kothari S.P., Giglio M.G., Zhou L., Haft D.H., Selengut J.D., Davidsen T.M., Yang Q., Zafar N., Ward N.L. J. Bacteriol. 188:6841-6850(2006) [PubMed: 16980487] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000158 Genomic DNA. Translation: ABI77284.1.
RefSeq	YP_761161.1. NC_008358.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0BZD2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4288261.
GenomeReviews	Gene locus HNE_2466 in contig CP000158_GR.
KEGG	hne:HNE_2466.
NMPDR	fig|228405.5.peg.2379.
PATRIC	32217785. VBIHypNep17450_2475.
TIGR	HNE_2466.
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	EQPAIRL.
ProtClustDB	CLSK2531921.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0BZD2_HYPNA

Accession

Primary (citable) accession number: Q0BZD2

Entry history

Integrated into UniProtKB/TrEMBL:	October 17, 2006
Last sequence update:	October 17, 2006
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)