SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0BVJ1

- ASSY_GRABC

UniProt

Q0BVJ1 - ASSY_GRABC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Argininosuccinate synthase

Gene
argG, GbCGDNIH1_0263
Organism
Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei46 – 461ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei97 – 971Citrulline By similarity
Binding sitei102 – 1021Citrulline By similarity
Binding sitei127 – 1271ATP; via amide nitrogen By similarity
Binding sitei129 – 1291Aspartate By similarity
Binding sitei133 – 1331Aspartate By similarity
Binding sitei133 – 1331Citrulline By similarity
Binding sitei134 – 1341Aspartate By similarity
Binding sitei137 – 1371Citrulline By similarity
Binding sitei188 – 1881Citrulline By similarity
Binding sitei197 – 1971Citrulline By similarity
Binding sitei273 – 2731Citrulline By similarity
Binding sitei285 – 2851Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 279ATP By similarity

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciGBET391165:GHON-268-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:GbCGDNIH1_0263
OrganismiGranulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Taxonomic identifieri391165 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGranulibacter
ProteomesiUP000001963: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 416416Argininosuccinate synthaseUniRule annotationPRO_0000263930Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi391165.GbCGDNIH1_0263.

Structurei

3D structure databases

ProteinModelPortaliQ0BVJ1.
SMRiQ0BVJ1. Positions 15-411.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0BVJ1-1 [UniParc]FASTAAdd to Basket

« Hide

MTRDIQTMAV KDVKKVVLAY SGGLDTSVIL RWLQTTYNCE VVTFTADLGQ    50
GEELEPARRK AEMFGVKEIF VDDLRETFVK DFVFPMFRAN AVYEGQYLLG 100
TSIARPLIAQ RQIEIAELTG ADAVAHGATG KGNDQVRFEL SYYALKPDVK 150
VIAPWREWDL TSRTKLLEFA EANQIPIAKD KRGEAPFSVD ANLLHSSSEG 200
KLLEDPAEEP DEIVYQRTIS PEAAPDKATI ITIDFEHGDP VAIDGIRLSP 250
ATLLAKLNEL GKANGIGRLD LVENRFVGMK SRGVYETPGG TILLVAHRGI 300
ESITLDREAA HLKDSLMPRY AELIYNGFWF SPERRMLQAA IDESQKSVTG 350
RVRLKLYKGN TIVIGRESPN SLYSLKHVTF EDDQGAYDQV DAQGFIKLQS 400
LRLRLAAIAG RRGGSL 416
Length:416
Mass (Da):46,235
Last modified:October 17, 2006 - v1
Checksum:i23AAA2BA61B153C6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000394 Genomic DNA. Translation: ABI61161.1.
RefSeqiYP_744084.1. NC_008343.1.

Genome annotation databases

EnsemblBacteriaiABI61161; ABI61161; GbCGDNIH1_0263.
GeneIDi4274482.
KEGGigbe:GbCGDNIH1_0263.
PATRICi22076553. VBIGraBet83793_0274.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000394 Genomic DNA. Translation: ABI61161.1 .
RefSeqi YP_744084.1. NC_008343.1.

3D structure databases

ProteinModelPortali Q0BVJ1.
SMRi Q0BVJ1. Positions 15-411.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 391165.GbCGDNIH1_0263.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABI61161 ; ABI61161 ; GbCGDNIH1_0263 .
GeneIDi 4274482.
KEGGi gbe:GbCGDNIH1_0263.
PATRICi 22076553. VBIGraBet83793_0274.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci GBET391165:GHON-268-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis."
    Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E., Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M.
    J. Bacteriol. 189:8727-8736(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1260 / CGDNIH1.

Entry informationi

Entry nameiASSY_GRABC
AccessioniPrimary (citable) accession number: Q0BVJ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 17, 2006
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi