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Q0BUJ8 (RF1_GRABC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peptide chain release factor 1

Short name=RF-1
Gene names
Name:prfA
Ordered Locus Names:GbCGDNIH1_0606
OrganismGranulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) [Complete proteome] [HAMAP]
Taxonomic identifier391165 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGranulibacter

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA By similarity. HAMAP-Rule MF_00093

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00093.

Post-translational modification

Methylated by PrmC. Methylation increases the termination efficiency of RF1 By similarity. HAMAP-Rule MF_00093

Sequence similarities

Belongs to the prokaryotic/mitochondrial release factor family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   PTMMethylation
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation release factor activity, codon specific

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 352352Peptide chain release factor 1 HAMAP-Rule MF_00093
PRO_0000263281

Amino acid modifications

Modified residue2291N5-methylglutamine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0BUJ8 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: A3816F05C06376CB

FASTA35239,011
        10         20         30         40         50         60 
MSFTANLDRI VARAEELRAS LSEGLNGDSF AAASRELAEL EPVVARIEEL WAAERGLAEA 

        70         80         90        100        110        120 
EAMLADPDMR ELAESEAEIL REKLPSLTRE IRIALLPKDE ADERSAILEI RPAAGGDEAS 

       130        140        150        160        170        180 
LFAAQLFSMY QRYAEIRGWR FEILEYDDTG LGGLKGGMAE ITGRSVFARL KYESGVHRVQ 

       190        200        210        220        230        240 
RVPATESQGR IHTSTVTVAV LPEAEDVDVQ VDEGDLRIDV YRASGAGGQH VNKTESAVRI 

       250        260        270        280        290        300 
THLPSGIVVA MQEEKSQHKN RAKAMKILKA RLYEQQRAAL HASRAADRRA QVGTGDRSER 

       310        320        330        340        350 
IRTYNFPQGR VSDHRINLTL YKIDRVMLGE LDDFVDALTA EDQAARLSAQ EL 

« Hide

References

[1]"Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis."
Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E., Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M.
J. Bacteriol. 189:8727-8736(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1260 / CGDNIH1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000394 Genomic DNA. Translation: ABI61504.1.
RefSeqYP_744427.1. NC_008343.1.

3D structure databases

ProteinModelPortalQ0BUJ8.
SMRQ0BUJ8. Positions 89-348.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING391165.GbCGDNIH1_0606.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI61504; ABI61504; GbCGDNIH1_0606.
GeneID4274965.
KEGGgbe:GbCGDNIH1_0606.
PATRIC22077289. VBIGraBet83793_0635.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0216.
HOGENOMHOG000074815.
KOK02835.
OMAYGQLKFE.
OrthoDBEOG6TN48J.

Enzyme and pathway databases

BioCycGBET391165:GHON-619-MONOMER.

Family and domain databases

Gene3D3.30.160.20. 1 hit.
HAMAPMF_00093. Rel_fac_1.
InterProIPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00019. prfA. 1 hit.
PROSITEPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRF1_GRABC
AccessionPrimary (citable) accession number: Q0BUJ8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 17, 2006
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families