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Q0BUB2 (Q0BUB2_GRABC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163
Gene names
Name:def2 HAMAP MF_00163
Ordered Locus Names:GbCGDNIH1_0693
OrganismGranulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) [Complete proteome] [HAMAP] EMBL ABI61591.1
Taxonomic identifier391165 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Granulibacter

Protein attributes

Sequence length205 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1701 By similarity HAMAP MF_00163
Metal binding1271Iron By similarity HAMAP MF_00163
Metal binding1691Iron By similarity HAMAP MF_00163
Metal binding1731Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
Q0BUB2 [UniParc].

Last modified October 17, 2006. Version 1.
Checksum: E48731869C13906F

FASTA20522,939
        10         20         30         40         50         60 
MQEATFFQGL PAGPSLPRGA WHRYIIFMSE TRTAELLPIL IAPHKTLKTR ARPVTAGDAS 

        70         80         90        100        110        120 
LIRDLVPRMF ATMYKAPGIG LAAPQIDSLL RLAVVDVSPD DQKAPLVLIN PDIIARSEEM 

       130        140        150        160        170        180 
ATREEGCLSL PNQYADVTRP ARIKLRYEDL DGSRREMEAD DLLATCIQHE IDHLDGILFV 

       190        200 
DHLSTLKRNM LMRRLAKEQR QNSGG

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References

[1]"Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis."
Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E., Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M.
J. Bacteriol. 189:8727-8736(2007) [PubMed: 17827295] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000394 Genomic DNA. Translation: ABI61591.1.
RefSeqYP_744513.1. NC_008343.1.

3D structure databases

ProteinModelPortalQ0BUB2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0BUB2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4276244.
GenomeReviewsGene locus GbCGDNIH1_0693 in contig CP000394_GR.
KEGGgbe:GbCGDNIH1_0693.
NMPDRfig|391165.8.peg.696.
PATRIC22077469. VBIGraBet83793_0724.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAEINSHIL.
PhylomeDBQ0BUB2.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ0BUB2_GRABC
AccessionPrimary (citable) accession number: Q0BUB2
Entry history
Integrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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